This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic +10 more
wiley +1 more source
Cell-Free DNA and Mitochondria in Parkinson's Disease. [PDF]
Wojtkowska M, Ambrosius F.
europepmc +1 more source
The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad +2 more
wiley +1 more source
Tardigrade-Derived Strategy for Low-Cost Storage of Cell-Free Expression Lysates. [PDF]
Meckelburg M +3 more
europepmc +1 more source
Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy
We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen +19 more
wiley +1 more source
Nanofluidics for Pioneering Synthetic Biology of Bottom-Up Cell-Free Molecular Systems. [PDF]
Wu S, Ma Q, Takai M, Xu Y.
europepmc +1 more source
Cell-free DNA genomic and fragmentomic features for early outcome prediction in large B cell lymphoma. [PDF]
Wang S +35 more
europepmc +1 more source
Diagnostic Testing After Positive Cell-Free DNA Screening for Sex Chromosome Aneuploidies: Clinical and Socioeconomic Determinants. [PDF]
Stevens BK +10 more
europepmc +1 more source
Early detection of gastric cancer with the assistance of cell-free DNA fragmentomics. [PDF]
Huang X +17 more
europepmc +1 more source
Using cell-free RNA to identify B- and T-cell clonality for diagnosis and monitoring of B- and T-cell neoplasms. [PDF]
Albitar A +11 more
europepmc +1 more source

