Results 241 to 250 of about 10,893,804 (303)

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

open access: yesMolecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic   +10 more
wiley   +1 more source

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

open access: yesMolecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad   +2 more
wiley   +1 more source

Tardigrade-Derived Strategy for Low-Cost Storage of Cell-Free Expression Lysates. [PDF]

open access: yesACS Synth Biol
Meckelburg M   +3 more
europepmc   +1 more source

Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy

open access: yesMolecular Oncology, EarlyView.
We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen   +19 more
wiley   +1 more source

Cell-free DNA genomic and fragmentomic features for early outcome prediction in large B cell lymphoma. [PDF]

open access: yesCell Rep Med
Wang S   +35 more
europepmc   +1 more source

Diagnostic Testing After Positive Cell-Free DNA Screening for Sex Chromosome Aneuploidies: Clinical and Socioeconomic Determinants. [PDF]

open access: yesPrenat Diagn
Stevens BK   +10 more
europepmc   +1 more source

Early detection of gastric cancer with the assistance of cell-free DNA fragmentomics. [PDF]

open access: yesClin Epigenetics
Huang X   +17 more
europepmc   +1 more source

Using cell-free RNA to identify B- and T-cell clonality for diagnosis and monitoring of B- and T-cell neoplasms. [PDF]

open access: yesFEBS Open Bio
Albitar A   +11 more
europepmc   +1 more source

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