Results 201 to 210 of about 6,347,699 (399)

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

DL4-μbeads induce T cell lineage differentiation from stem cells in a stromal cell-free system. [PDF]

open access: yesNat Commun, 2021
Trotman-Grant AC   +9 more
europepmc   +1 more source

Development of a reconfigurable assembly system with an integrated information management system [PDF]

open access: yes, 2014
Thesis (M. Tech. (Engineering Electrical)) -- Central University of Technology, Free State, [2014]This dissertation evaluates the software and hardware components used to develop a Reconfigurable Assembly System with an Integrated Information Management
Smith, Lyle. Christopher.
core  

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov   +3 more
wiley   +1 more source

Spatial organization of cytokinesis signaling reconstituted in a cell-free system

open access: yesScience, 2014
Phuong A. Nguyen   +6 more
semanticscholar   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

Coupling between clathrin-dependent endocytic budding and F-BAR-dependent tubulation in a cell-free system

open access: yesNature Cell Biology, 2010
Min Wu   +6 more
semanticscholar   +1 more source

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