Results 41 to 50 of about 88,541,361 (296)

Mesenchymal cell invasion requires cooperative regulation of persistent microtubule growth by SLAIN2 and CLASP1 [PDF]

, 2016
Microtubules regulate signaling, trafficking, and cell mechanics, but the respective contribution of these functions to cell morphogenesis and migration in 3D matrices is unclear.
Noordstra, Ivar, Katrukha, Eugene A., Derksen, Patrick W. B., Katrukha, Eugene A, van Amersfoort, Miranda, Ter Hoeve, Natalie D, Celbiologie, Bouchet, Benjamin P, Derksen, Patrick W B, Dogterom, Marileen, Ammon, York-Christoph, Bouchet, Benjamin P., Hodgson, Louis, Sub Cell Biology, Akhmanova, Anna, ter Hoeve, Natalie D.   +15 more
core   +2 more sources

Microtubules in 3D cell motility [PDF]

, 2017
Three-dimensional (3D) cell motility underlies essential processes, such as embryonic development, tissue repair and immune surveillance, and is involved in cancer progression. Although the cytoskeleton is a well-studied regulator of cell migration, most
Sub Cell Biology, Celbiologie, Anna Akhmanova, Bouchet, Benjamin P, Benjamin P. Bouchet, Akhmanova, Anna   +5 more
core   +1 more source

Timing the Landmark Events in the Evolution of Clear Cell Renal Cell Cancer: TRACERx Renal.

, 2022
Clear cell renal cell carcinoma (ccRCC) is characterized by near-universal loss of the short arm of chromosome 3, deleting several tumor suppressor genes. We analyzed whole genomes from 95 biopsies across 33 patients with clear cell renal cell carcinoma.
Raine, K, Yates, LR, Teague, J, Lopez, JI, Gore, M, Rowan, A, Mitchell, TJ, Lynch, AG, Au, L, Stewart, A, Litchfield, K, Turajlic, S, Tarpey, P, Chandra, A, Csabai, I, Swanton, C, Fotiadis, N, Lynch, J, Soultati, A, Challacombe, B, Xu, H, Hazell, S, Stamp, G, Elaidi, R, Horswell, S, Campbell, PJ, Chowdhury, S, Butler, AP, Rudman, S, Wedge, DC, Futreal, PA, Nicol, D, Farmery, JHR, O'Brien, T, Maura, F, McGranahan, N, TRACERx Renal Consortium,, Spain, L, Stewart, GD, Szallasi, Z, Martincorena, I, Stares, M, Fernando, A, Larkin, J, Oudard, S, Pickering, L, Chambers, T, Angelopoulos, N   +47 more
core   +1 more source

Two homologous Agr-like quorum-sensing systems cooperatively control adherence, cell morphology, and cell viability properties in Lactobacillus plantarum WCFS1 [PDF]

, 2008
A two-component regulatory system of Lactobacillus plantarum, encoded by genes designated lamK and lamR (hpk10 and rrp10), was studied. The lamK and lamR genes encode proteins which are highly homologous to the quorum-sensing histidine kinase LamC and ...
Vos, W.M., de, Kleerebezem, M., Kunuki, Ryoko, Ingham, C.J., Sturme, Mark, Nakayama, J., Vaughan, Elaine, Kunuki, R., Nakayama, Jiro, Sturme, M.H.J., Fujii, Toshio, Kleerebezem, Michiel, Molenaar, D., Fujii, T., Vaughan, E.E., Ingham, Colin, Beerthuyzen, Marke, Molenaar, Douwe, de Vos, Willem, Molenaar, Douwe; id_orcid, de Vos, W.M., Beerthuyzen, M.M.   +21 more
core   +1 more source

Creating Contacts Between Replication and Movement at Plasmodesmata – A Role for Membrane Contact Sites in Plant Virus Infections?

Frontiers in Plant Science, 2020
To infect their hosts and cause disease, plant viruses must replicate within cells and move throughout the plant both locally and systemically. RNA virus replication occurs on the surface of various cellular membranes, whose shape and composition become ...
Amit Levy, Amit Levy, Jens Tilsner, Jens Tilsner   +3 more
doaj   +1 more source

Cell Competition and its role in the regulation of cell fitness from development to cancer [PDF]

, 2016
Cell competition is a cell fitness-sensing mechanism conserved from insects to mammals that eliminates those cells that, although viable, are less fit than their neighbors. An important implication of cell competition is that cellular fitness is not only
di gregorio, A, Rodriguez, T, Bowling, S
core   +1 more source

Selective Targeting of Mobile mRNAs to Plasmodesmata for Cell-to-Cell Movement [PDF]

Plant Physiology, 2018
Many plant mRNAs move from cell to cell or long distance to execute non-cell-autonomous functions. These mobile mRNAs traffic through the phloem to regulate many developmental processes, but despite the burgeoning discovery of mobile mRNAs, little is known about the mechanism underlying the intracellular sorting of these mRNAs.
Kai-Ren Luo, Nien-Chen Huang, Tien-Shin Yu   +2 more
openaire   +2 more sources

Patterns of cell movement within the Dictyostelium slug revealed by cell type-specific, surface labeling of living cells [PDF]

, 1994
There are cells acattered in the rear, prespore region of the Dictyostelium slug that share many of the properties of the prestalk cells and that are therefore called anterior-like cells (ALCs).
Early, Anne, Abe, Tomoaki, Siegert, Florian, Weijer, Cornelis J., Williams, Jeffrey   +4 more
core   +1 more source

Single-cell genome-wide association reveals a nonsynonymous variant in ERAP1 confers increased susceptibility to influenza virus [PDF]

, 2022
During pandemics, individuals exhibit differences in risk and clinical outcomes. Here, we developed single-cell high-throughput human in vitro susceptibility testing (scHi-HOST), a method for rapidly identifying genetic variants that confer resistance ...
Ko, Dennis C., Bergstrom, Emma, Brennan, Richard G, Brennan, Richard G., Jack Anderson, Christopher W. Woods, Erica J. Washington, Chiu, Christopher, Harding, Alfred T., Micah T. McClain, McClain, Micah T., Alfred T. Harding, Schott, Benjamin H, Ko, Dennis C, Gregory, Simon G., Zhu, Xinyu, Bourgeois, Jeffrey S, Gregory, Simon G, McClain, Micah T, Emily R. Ko, Heaton, Nicholas S., Dennis C. Ko, Richard G. Brennan, Zoe Gardener, Paterson, Suzanna, Nicholas S. Heaton, Wang, Liuyang, Washington, Erica J., Woods, Christopher W., Liuyang Wang, Heaton, Nicholas S, Benjamin H. Schott, Schott, Benjamin H., Woods, Christopher W, Thomas W. Burke, Anderson, Jack, Christopher Chiu, Bourgeois, Jeffrey S., Suzanna Paterson, Ko, Emily R, Washington, Erika J, Emma Bergstrom, Xinyu Zhu, Harding, Alfred T, Burke, Thomas W., Jeffrey S. Bourgeois, Gardener, Zoe, Ko, Emily R., Burke, Thomas W, Simon G. Gregory   +49 more
core   +1 more source

Cell-to-cell stimulation of movement in nonmotile mutants of Myxococcus [PDF]

Proceedings of the National Academy of Sciences, 1977
A large number of nonmotile mutants of the gliding bacterium Myxococcus xanthus have been isolated and partly characterized. About [unk] of these mutants are conditional mutants of a novel kind: mutant cells become transiently motile after contact with nonmutant cells or with cells of a ...
J, Hodgkin, D, Kaiser
openaire   +2 more sources