Results 51 to 60 of about 636,142 (250)

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Cell‐to‐cell movement of TMV RNA is temperature‐dependent and corresponds to the association of movement protein with microtubules [PDF]

The Plant Journal, 2000
SummaryThe movement protein (MP) of tobacco mosaic virus (TMV) is essential for spread of the viral RNA genome from cell to cell. During infection, the MP associates with microtubules, and it has been proposed that the cytoskeleton transports the viral ribonucleoprotein complex from ER sites of synthesis to plasmodesmata through which infection spreads
Boyko V, Ferralli J, Heinlein M
openaire   +3 more sources

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

The roles of movement and coat proteins in the transport of tobamoviruses between plant cells

Frontiers in Plant Science
Tobamovirus is a large group of positive-sense, single-stranded RNA viruses that cause diseases in a broad range of plant species, including many agronomically important crops. The number of known Tobamovirus species has been on the rise in recent years,
Yumin Kan, Vitaly Citovsky
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

A Protocol to Measure the Extent of Cell-to-cell Movement of RNA Viruses in Planta

Bio-Protocol, 2014
Here, we present a simple and rapid protocol to measure the extent of cell-to-cell movement of RNA viruses in planta. To do that, the green fluorescent protein (GFP) gene was incorporated into the genome of Melon necrotic spot virus (MNSV) as a coat ...
José Navarro, Marta Serra-Soriano, Vicente Pallás   +2 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Genetic Analysis of the Cell-to-Cell Movement of Beet Yellows Closterovirus

Virology, 2000
A beet yellows closterovirus (BYV) variant expressing green fluorescent protein and leaves of BYV local lesion host Claytonia perfoliata were used to reveal genetic requirements for BYV cell-to-cell movement in leaf epidermis and mesophyll. A series of mutations targeting genes that are not involved in amplification of the viral positive-strand RNA was
Alzhanova, Dina V., Hagiwara, Yuka, Peremyslov, Valery V., Dolja, Valerian V.   +3 more
openaire   +2 more sources

Cucumber mosaic virus-Plant Interactions: Identification of 3a Protein Sequences Affecting Infectivity, Cell-to-Cell Movement, and Long-distance Movement

Molecular Plant-Microbe Interactions, 2001
Mutants of the Cucumber mosaic virus (CMV) movement protein (MP) were generated and analyzed for their effects on virus movement and pathogenicity in vivo.
Qiubo Li, Ki Hyun Ryu, Peter Palukaitis
doaj   +1 more source

A live-imaging protocol to track cell movement in the Xenopus embryo

STAR Protocols, 2021
Summary: Tracking individual cell movement during development is challenging, particularly in tissues subjected to major remodeling. Currently, most live imaging techniques in Xenopus are limited to tissue explants and/or to superficial cells.
Alexandre Chuyen, Fabrice Daian, Andrea Pasini, Laurent Kodjabachian   +3 more
doaj   +1 more source