Results 61 to 70 of about 88,541,361 (296)

Non-cell-autonomous small RNA silencing in Arabidopsis female gametes. [PDF]

, 2023
In recent years, small RNA movement has been both hypothesized and shown to be an integral part of the epigenetic DNA methylation reprogramming occurring during plant reproduction.1It was suggested that the release of epigenetic silencing in accessory ...
Schröder, Jens A, Bonnet, Diane M V, Jullien, Pauline E   +2 more
core   +1 more source

Compatibility of the movement protein and the coat protein of cucumoviruses is required for cell-to-cell movement

Journal of General Virology, 2004
For the cell-to-cell movement of cucumoviruses both the movement protein (MP) and the coat protein (CP) are required. These are not reversibly exchangeable betweenCucumber mosaic virus(CMV) andTomato aspermy virus(TAV). The MP of CMV is able to function with the TAV CP (chimera RT), but TAV MP is unable to promote the cell-to-cell movement in the ...
Katalin, Salánki, Ákos, Gellért, Emese, Huppert, Gábor, Náray-Szabó, Ervin, Balázs   +4 more
openaire   +2 more sources

Transitivity‐dependent and ‐independent cell‐to‐cell movement of RNA silencing [PDF]

The EMBO Journal, 2003
One manifestation of RNA silencing, known as post-transcriptional gene silencing (PTGS) in plants and RNA interference (RNAi) in animals, is a nucleotide sequence-specific RNA turnover mechanism with the outstanding property of propagating throughout the organism, most likely via movement of nucleic acids.
Christophe, Himber, Patrice, Dunoyer, Guillaume, Moissiard, Christophe, Ritzenthaler, Olivier, Voinnet   +4 more
openaire   +2 more sources

Active growth signaling promotes senescence and cancer cell sensitivity to CDK7 inhibition

, 2023
Tumor growth is driven by continued cellular growth and proliferation. Cyclin-dependent kinase 7's (CDK7) role in activating mitotic CDKs and global gene expression makes it therefore an attractive target for cancer therapies.
Bertoli, Cosetta, Lauring, Josh, Vuina, Karla, Bertomeu, Thierry, Sava, Georgina, Huard, Caroline, Meneguello, Leticia, Kriston-Vizi, Janos, Maizels, Rory J, Tyers, Mike, de Bruin, Robertus AM, Wilson, Gemma A, Coulombe-Huntington, Jasmin, Ali, Simak   +13 more
core   +1 more source

Effects of brefeldin A on the localization of Tobamovirus movement protein and cell-to-cell movement of the virus

Virology, 2007
It has been demonstrated that the subcellular location of Tobamovirus movement protein (MP) which was fused with green fluorescent protein (MP:GFP) changed during the infection process. However, the intracellular route through which MP is transported and its biological meaning are still obscure.
Tagami, Yuko, Watanabe, Yuichiro
openaire   +2 more sources

HSP70 homolog functions in cell-to-cell movement of a plant virus [PDF]

Proceedings of the National Academy of Sciences, 1999
Plant closteroviruses encode a homolog of the HSP70 (heat shock protein, 70 kDa) family of cellular proteins. To facilitate studies of the function of HSP70 homolog (HSP70h) in viral infection, the beet yellows closterovirus (BYV) was modified to express green fluorescent protein.
V V, Peremyslov, Y, Hagiwara, V V, Dolja
openaire   +2 more sources

Broad bean wilt virus 2 movement protein VP37 relocalizes the host co-chaperone HOP from the nucleus to plasmodesmata to promote viral intercellular movement

Plant Stress
Plant viruses exploit host cellular machinery to fold, stabilize, and target their movement proteins (MPs) to plasmodesmata (PD), enabling viral cell-to-cell and systemic spread.
Seok-Yeong Jang, Myung-Hwi Kim, Sora Kim, Buyoung Kim, Andika Septiana Suryaningsih, Yu Lim Park, Sun-Jung Kwon, Jang-Kyun Seo   +7 more
doaj   +1 more source

Tubule-guided cell-to-cell movement of a plant virus requires class XI myosin motors. [PDF]

PLoS Pathogens, 2011
Cell-to-cell movement of plant viruses occurs via plasmodesmata (PD), organelles that evolved to facilitate intercellular communications. Viral movement proteins (MP) modify PD to allow passage of the virus particles or nucleoproteins.
Khalid Amari, Alexander Lerich, Corinne Schmitt-Keichinger, Valerian V Dolja, Christophe Ritzenthaler   +4 more
doaj   +1 more source

Referral Patterns and Diagnostic Timeliness in Pediatric Cancer: A Hospital‐Based Study in Indonesia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Timely diagnosis and treatment are critical for improving survival among children with cancer. In low‐ and middle‐income countries (LMICs), delays are common and may be influenced by fragmented referral pathways and diagnostic limitations.
Nur Melani Sari, Regina Hadi Putri, Fatimah Assyifa, Judith Spijkerman, Gertjan Johannes Kaspers, Susi Susanah   +5 more
wiley   +1 more source

PI3K-C2 alpha Knockdown Results in Rerouting of Insulin Signaling and Pancreatic Beta Cell Proliferation [PDF]

, 2018
Insulin resistance is a syndrome that affects multiple insulin target tissues, each having different biological functions regulated by insulin. A remaining question is to mechanistically explain how an insulin target cell/tissue can be insulin resistant ...
Berggren, PO, Leibiger, IB, Paschen, M, Yunn, NO, Lim, JH, Leibiger, B, Ryu, SH, Moede, T, Pereira, T   +8 more
core   +1 more source