Results 301 to 310 of about 271,506 (342)

Signalling pathways underlying neural cell adhesion molecule‐mediated survival of dopaminergic neurons

European Journal of Neuroscience, 2007
AbstractStimulation of the neural cell adhesion molecule (NCAM) by homophilic interactions is known to lead to neurite outgrowth as well as to neuronal survival. Whereas a complex network of signalling molecules is known to be of importance to NCAM‐mediated neurite extension, only limited information is available regarding signalling underlying NCAM ...
Ditlevsen, D.K., Berezin, V., Bock, Elisabeth Marianne   +2 more
openaire   +2 more sources

F3/contactin, a neuronal cell adhesion molecule implicated in axogenesis and myelination

Biology of the Cell, 2002
AbstractA general feature of the cell adhesion molecules belonging to the immunoglobulin family (Ig‐CAMs) is to display a modular structure that provides a framework for multiple binding sites for other recognition molecules. Among this family, F3/contactin is a glycan phosphatidyl‐inositol (GPI)‐anchored molecule expressed by neurons that displays the
Julien, Falk, Carine, Bonnon, Jean-Antoine, Girault, Catherine, Faivre-Sarrailh   +3 more
openaire   +2 more sources

Further Studies of Elevated Cerebrospinal Fluid Neuronal Cell Adhesion Molecule in Schizophrenia

Biological Psychiatry, 1998
The purposes of the present study were to attempt to replicate a previous finding of increased cerebrospinal fluid (CSF) neuronal cell adhesion molecule (N-CAM) in schizophrenia, and to assess whether the increases could be related to medication, clinical state effects, or brain structural measures.CSF N-CAM was measured by the Western blot technique ...
D P, van Kammen, M, Poltorak, M E, Kelley, J K, Yao, J A, Gurklis, J L, Peters, J J, Hemperly, R D, Wright, W J, Freed   +8 more
openaire   +2 more sources

NCAM2/OCAM/RNCAM: Cell adhesion molecule with a role in neuronal compartmentalization

The International Journal of Biochemistry & Cell Biology, 2012
Neural cell adhesion molecules 2 (NCAM2/OCAM/RNCAM), is a paralog of NCAM1. The protein exists in a transmembrane and a lipid-anchored isoform, and has an ectodomain consisting of five immunoglobulin modules and two fibronectin type 3 homology modules. Structural models of the NCAM2 ectodomain reveal that it facilitates cell adhesion through reciprocal
Winther, Malene, Berezin, Vladimir, Walmod, Peter Schledermann   +2 more
openaire   +3 more sources

N-linked oligosaccharides are not required for neuron-neuron interactions mediated by neural cell adhesion molecule

Neuroscience Letters, 1988
Recent studies have described the role of various regions of the neural cell adhesion molecule (NCAM) in cell-cell interactions. Monoclonal antibodies (L2/HNK-1) directed against a sulfated, glucuronic acid-containing, N-linked carbohydrate epitope have also been shown to inhibit NCAM-mediated neural cell adhesion.
G J, Cole, M, Schachner, S J, Fliesler
openaire   +2 more sources

Polarized targeting of IgLON cell adhesion molecule OBCAM to dendrites in cultured neurons

Brain Research, 2003
Opioid-binding cell adhesion molecule (OBCAM) belongs to the immunoglobulin superfamily CAMs and shows a dendritically polarized distribution in hypothalamic magnocellular neurons. In the present study, the cellular localization of OBCAM was monitored in cultured cortical and hippocampal neurons to examine its polarized distribution.
Seiji, Miyata, Naoko, Matsumoto, Shohei, Maekawa   +2 more
openaire   +2 more sources

Integrins and cell adhesion molecules: neuronal receptors that regulate axon growth on extracellular matrices and cell surfaces.

Developmental Neuroscience, 1989
L. Reichardt, J. Bixby, D. E. Hall, M. Ignatius, K. Neugebauer, K. Tomaselli   +5 more
semanticscholar   +1 more source

Neural cell adhesion molecules, neuronal development and lead toxicity.

Neurotoxicology, 1994
The major families of neural cell recognition molecules and the mechanisms by which they regulate neural development are described. The role of the neural cell adhesion molecule (NCAM) isoforms in organizing tissue structure and pattern is discussed in detail and their degree of sialylation is proposed to regulate the intimacy of cell-cell interaction,
openaire   +1 more source

S.4.01 Neuroplasticity and neuronal cell adhesion molecules

European Neuropsychopharmacology, 2009
E. Bock, P.S. Walmod, T. Secher, V. Berezin   +3 more
openaire   +1 more source

Clinical insights into small cell lung cancer: Tumor heterogeneity, diagnosis, therapy, and future directions

Ca-A Cancer Journal for Clinicians, 2023
Balazs Dome
exaly