Results 41 to 50 of about 271,506 (342)
Expression profiling of RNA transcripts during neuronal maturation and ischemic injury. [PDF]
PLoS ONE, 2014 Neuronal development is a pro-survival process that involves neurite growth, synaptogenesis, synaptic and neuronal pruning. During development, these processes can be controlled by temporal gene expression that is orchestrated by both long non-coding ...
Prameet Kaur +4 more
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Computational and Structural Biotechnology Journal, 2021 The discovery of conserved protein motifs can, in turn, unveil important regulatory signals, and when properly designed, synthetic peptides derived from such motifs can be used as biomimetics for biotechnological and therapeutic purposes.
Giorgia Scapin +9 more
doaj +1 more source
Spatiomechanical Modulation of EphB4-Ephrin-B2 Signaling in Neural Stem Cell Differentiation. [PDF]
, 2018 Interactions between EphB4 receptor tyrosine kinases and their membrane-bound ephrin-B2 ligands on apposed cells play a regulatory role in neural stem cell differentiation.
Chung, Jean +6 more
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Altered expression of neuronal cell adhesion molecules induced by nerve injury and repair
Journal of Cell Biology, 1986 Peripheral nerve injury results in short-term and long-term changes in both neurons and glia. In the present study, immunohistological and immunoblot analyses were used to examine the expression of the neural cell adhesion molecule (N-CAM) and the neuron-
J. K. Daniloff +4 more
semanticscholar +1 more source
Cell‐cell adhesion by homophilic interaction of the neuronal recognition molecule axonin‐1 [PDF]
European Journal of Biochemistry, 1993 The axonal surface glycoprotein axonin‐1, which occurs both as a glycosyl‐phosphatidylinositol‐anchored membrane‐bound form and a secreted form, promotes neurite outgrowth and is thought to be involved in axon‐guidance mechanisms in the developing nervous system.
C, Rader +5 more
openaire +2 more sources
Communications Biology, 2023 RAB35 is a multifunctional small GTPase that regulates endocytic recycling, cytoskeletal rearrangement, and cytokinesis. However, its physiological functions in mammalian development remain unclear.
Ikuko Maejima +11 more
doaj +1 more source
Shedding of APP limits its synaptogenic activity and cell adhesion properties
Frontiers in Cellular Neuroscience, 2014 The Amyloid precursor protein (APP) plays a central role in Alzheimer’s disease (AD) and has essential synapse promoting functions. Synaptogenic activity as well as cell adhesion properties of APP presumably depend on trans-cellular dimerization via its ...
Ronny eStahl +9 more
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Prevention of neuronal cell death by neural adhesion molecules L1 and CHL1.
Journal of Neurobiology, 1999 The effects of L1-Fc and CHL1-Fc fusion proteins on neuronal survival were investigated. Cerebellar granule neurons of mouse and hippocampal neurons of rat embryo undergo apoptosis when cultured in serum-free medium. Treatment with chimeric proteins containing the extracellular domains of the neural adhesion molecules L1 or CHL1 fused to the Fc region ...
Suzhen Chen +8 more
semanticscholar +3 more sources
Antimicrobial peptides and complement in neonatal hypoxia-ischemia induced brain damage [PDF]
, 2015 Hypoxic-ischemic encephalopathy (HIE) is a clinical condition in the neonate, resulting from oxygen deprivation around the time of birth. HIE affects 1-5/1000 live births worldwide and is associated with the development of neurological deficits ...
Hristova, M, Rocha-Ferreira, E
core +1 more source
Contactin-1/F3 Regulates Neuronal Migration and Morphogenesis Through Modulating RhoA Activity
Frontiers in Molecular Neuroscience, 2018 During neocortical development, newborn neurons migrate along radial fibers from the germinal ventricular zone (VZ) toward the cortical plate (CP) to populate the cerebral cortex.
Yi-An Chen +4 more
doaj +1 more source