Results 61 to 70 of about 271,506 (342)

Morphogenetic and neuronal characterization of human neuroblastoma multicellular spheroids cultured under undifferentiated and all-trans-retinoic acid-differentiated conditions [PDF]

BMB Reports, 2013
In this study, we aimed to compare the morphogenetic andneuronal characteristics between monolayer cells andspheroids. For this purpose, we established spheroid formationby growing SH-SY5Y cells on the hydrophobic surfaces ofthermally-collapsed elastin ...
Gwon-Soo Jung, Kyeong-Min Lee, Jin-Kyu Park, Seong-Kyoon Choi, Won Bae Jeon   +4 more
doaj   +1 more source

Review: Dystroglycan in the Nervous System [PDF]

, 2007
Dystroglycan is part of a large complex of proteins, the dystrophin-glycoprotein complex, which has been implicated in the pathogenesis of muscular dystrophies for a long time.
Matthias Samwald
core   +2 more sources

Neuron Glia-Related Cell Adhesion Molecule (NrCAM) Promotes Topographic Retinocollicular Mapping

PLoS ONE, 2013
NrCAM (Neuron-glial related cell adhesion molecule), a member of the L1 family of cell adhesion molecules, reversibly binds ankyrin and regulates axon growth, but it has not been studied for a role in retinotopic mapping. During development of retino-collicular topography, NrCAM was expressed uniformly in retinal ganglion cells (RGCs) along both ...
Jinxia Dai, Mona Buhusi, Galina P Demyanenko, Leann H Brennaman, Martin Hruska, Matthew B Dalva, Patricia F Maness   +6 more
openaire   +4 more sources

Association of the neuronal cell adhesion molecule (NRCAM) gene variants with autism [PDF]

The International Journal of Neuropsychopharmacology, 2008
Autism is a severe neurodevelopmental disorder of early childhood. Genetic factors play an important role in the aetiology of the disorder. In this study, we considered the NRCAM gene as a candidate gene of autism. This gene is expressed in the central nervous system and located in the 7q region, a susceptibility locus of autism.
Tetsuya, Marui, Ikuko, Funatogawa, Shinko, Koishi, Kenji, Yamamoto, Hideo, Matsumoto, Ohiko, Hashimoto, Eiji, Nanba, Hisami, Nishida, Toshiro, Sugiyama, Kiyoto, Kasai, Keiichiro, Watanabe, Yukiko, Kano, Tsukasa, Sasaki, Nobumasa, Kato   +13 more
openaire   +2 more sources

Mechanisms of parasite‐mediated disruption of brain vessels

FEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira, Sílvia Arroz‐Madeira, Cláudio A. Franco, Sara Silva Pereira   +3 more
wiley   +1 more source

Alternative splicing controls teneurin-3 compact dimer formation for neuronal recognition

Nature Communications
Neuronal network formation is facilitated by recognition between synaptic cell adhesion molecules at the cell surface. Alternative splicing of cell adhesion molecules provides additional specificity in forming neuronal connections.
Christos Gogou, J. Wouter Beugelink, Cátia P. Frias, Leanid Kresik, Natalia Jaroszynska, Uwe Drescher, Bert J. C. Janssen, Robert Hindges, Dimphna H. Meijer   +8 more
doaj   +1 more source

Proteoglycans and neuronal migration in the cerebral cortex during development and disease

Frontiers in Neuroscience, 2015
Chondroitin sulfate proteoglycans and heparan sulfate proteoglycans are major constituents of the extracellular matrix and the cell surface in the brain. Proteoglycans bind with many proteins including growth factors, chemokines, axon guidance molecules,
Nobuaki eMaeda
doaj   +1 more source

The potential of Antheraea pernyi silk for spinal cord repair [PDF]

, 2017
This work was supported by the Institute of Medical Sciences of the University of Aberdeen, Scottish Rugby Union and RS McDonald Charitable Trust. We are grateful to Mr Nicholas Hawkins from Oxford University and Ms Annette Raffan from the University of ...
Huang, W, Knight, D, Lesage, S, Rajnicek, A M, Varone, A, Vollrath, F   +5 more
core   +2 more sources

Time after time – circadian clocks through the lens of oscillator theory

FEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo, Carolin Ector, Hanspeter Herzel   +2 more
wiley   +1 more source

Pten regulates endocytic trafficking of cell adhesion and Wnt signaling molecules to pattern the retina

Cell Reports
Summary: The retina is exquisitely patterned, with neuronal somata positioned at regular intervals to completely sample the visual field. Here, we show that phosphatase and tensin homolog (Pten) controls starburst amacrine cell spacing by modulating ...
Yacine Touahri, Joseph Hanna, Nobuhiko Tachibana, Satoshi Okawa, Hedy Liu, Luke Ajay David, Thomas Olender, Lakshmy Vasan, Alissa Pak, Dhruv Nimesh Mehta, Vorapin Chinchalongporn, Anjali Balakrishnan, Robert Cantrup, Rajiv Dixit, Pierre Mattar, Fermisk Saleh, Yaroslav Ilnytskyy, Monzur Murshed, Paul E. Mains, Igor Kovalchuk, Julie L. Lefebvre, Hon S. Leong, Michel Cayouette, Chao Wang, Antonio del Sol, Marjorie Brand, Benjamin E. Reese, Carol Schuurmans   +27 more
doaj   +1 more source