Results 101 to 110 of about 1,625,351 (310)
G-quadruplexes and mRNA localization [PDF]
arXiv, 2013 G-quadruplexes represent a novelty for molecular biology. Their role inside the cell remains mysterious. We investigate a possible correlation with mRNA localization. In particular, we hypothesize that Gquadruplexes influence fluid dynamics.
arxiv
Cyclin-dependent kinases as drug targets for cell growth and proliferation disorders. A role for systems biology approach in drug development. Part II - CDKs as drug targets in hypertrophic cell growth. Modelling of drugs targeting CDKs [PDF]
, 2012 Cyclin-dependent kinases (CDKs) are key regulators of cell growth and proliferation. Impaired regulation of their activity leads to various diseases such as cancer and heart hypertrophy.
Idowu, Michael A.
core +2 more sources
Functional variation among LPMOs revealed by the inhibitory effects of cyanide and buffer ions
FEBS Letters, EarlyView.This study addresses the inhibition of lytic polysaccharide monooxygenases (LPMOs) by cyanide and explains how and why the magnitude of observed inhibitory effects depends on the way LPMO reactions are setup and on the type of LPMO. Enzymes known as lytic polysaccharide monooxygenases (LPMOs) are mono‐copper polysaccharide‐degrading peroxygenases that ...
Ole Golten +10 more
wiley +1 more source
Cell biology perspectives in phage biology
Frontiers in Bioscience, 2012 Cellular biology has long been restricted to large cellular organisms. However, as the resolution of microscopic methods increased, it became possible to study smaller cells, in particular bacterial cells. Bacteriophage biology is one aspect of bacterial cell biology that has recently gained insight from cell biology.
openaire +3 more sources
Vascular smooth muscle–specific YAP/TAZ deletion triggers aneurysm development in mouse aorta
JCI Insight, 2023 Inadequate adaption to mechanical forces, including blood pressure, contributes to development of arterial aneurysms. Recent studies have pointed to a mechanoprotective role of YAP and TAZ in vascular smooth muscle cells (SMCs).
Marycarmen Arévalo Martínez +14 more
doaj +1 more source
FEBS Letters, EarlyView.Low‐density lipoprotein receptor‐related protein 6 (LRP6) is a key receptor for the Wnt antagonist Dickkopf1 (DKK1). DKK1 protein expression is induced in a bleomycin (BLM)‐induced lung injury model. We show that DKK1 induces proinflammatory and profibrotic genes in lung fibroblasts.
Eun‐Ah Sung +6 more
wiley +1 more source
iScience, 2022 Summary: How the ataxia telangiectasia mutated (ATM) protein kinase, a core protein in DNA damage response, is regulated at post-transcription level remains unclear.
Yarui Zhang +8 more
doaj
TIAM1 acts as an actin organization regulator to control adipose tissue–derived pericyte cell fate
JCI Insight, 2023 Pericytes are multipotent mesenchymal precursor cells that demonstrate tissue-specific properties. In this study, by comparing human adipose tissue– and periosteum-derived pericyte microarrays, we identified T cell lymphoma invasion and metastasis 1 ...
Ginny Ching-Yun Hsu +12 more
doaj +1 more source
A decade of molecular cell atlases [PDF]
arXiv, 2022 The recent opinion article "A decade of molecular cell atlases" by Stephen Quake narrates the incredible single-cell genomics technology advances that have taken place over the last decade, and how they have translated to increasingly resolved cell atlases. However the sequence of events described is inaccurate and contains several omissions and errors.
arxiv
The Evolution of Cell Communication: The Road not Taken. [PDF]
, 2009 In the post-genomic era the complex problem of evolutionary biology can be tackled from the top-down, the bottom-up, or from the middle-out. Given the emergent and contingent nature of this process, we have chosen to take the latter approach, both as a ...
Rehan, VK, Torday, JS
core +1 more source