Results 101 to 110 of about 8,046,202 (313)

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

MYADM regulates Rac1 targeting to ordered membranes required for cell spreading and migration [PDF]

, 2011
Membrane organization into condensed domains or rafts provides molecular platforms for selective recruitment of proteins. Cell migration is a general process that requires spatiotemporal targeting of Rac1 to membrane rafts.
Kremer, Leonor, Enrich Bastús, Carles, Miguel A. Alonso, Marcos-Ramiro, Beatriz, Reglero-Real, Natalia, Ana Ruiz-Sáenz, Ruiz-Sáenz, Ana, Alonso, Miguel Ángel, María Calvo, Marcos Ramiro, Beatriz, Millán, Jaime, Leonor Kremer, Correas Hornero, María Isabel, Natalia Reglero-Real, Aranda, Juan Francisco, Carlos Enrich, Aranda, Juan F., Isabel Correas, Calvo Ademuz, Maria, Correas, Isabel, Alonso, Miguel A., Beatriz Marcos-Ramiro, Enrich, Carlos, Juan F. Aranda, Calvo, Maria, Jaime Millán, Reglero Real, Natalia   +26 more
core   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Cell biology and molecular biology.

Advances in cytopharmacology, 1968
info:eu-repo/semantics ...
openaire   +4 more sources

The Tyrosine Phosphatase CD148 is Excluded from the Immunologic Synapse and Down-regulates Prolonged T Cell Signaling [PDF]

, 2003
?? Joseph Lin and Arthur Weis, 2011. Originally published in The Journal of Cell Biology. doi: 10.1083/jcb.200303040.CD148 is a receptor-like protein tyrosine phosphatase\ud up-regulated on T cells after T cell receptor\ud (TCR) stimulation.
Arthur Weiss, Weiss, Arthur, Lin, Joseph, Joseph Lin   +3 more
core   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Hematopoietic Signaling Mechanism Revealed from a Stem/Progenitor Cell Cistrome

, 2018
Thousands of cis-elements in genomes are predicted to have vital functions. Although conservation, activity in surrogate assays, polymorphisms, and disease mutations provide functional clues, deletion from endogenous loci constitutes the gold-standard ...
Rajendran Sanalkumar, Jin Soo Kim, Chandler Zuo, Yoon-A Kang, Sunduz Keles, Prithvia Devadas, Duk Hyoung Kim, Emery H. Bresnick, Kyle J. Hewitt, Rajalekshmi Prathibha, Kirby D Johnson, Colin N. Dewey   +11 more
core   +1 more source

Transcription factor Sp1 is essential for early embryonic development but dispensable for cell growth and differentiation. [PDF]

, 1997
Transcription factor Sp1 has been implicated in the expression of many genes. Moreover, it has been suggested that Sp1 is linked to the maintenance of methylation-free CpG islands, the cell cycle, and the formation of active chromatin structures. We have
Marin, MS, Visser, WJ, Marin, M., Visser, P. (Pim), Karis, A. (Alar), Visser, Pim, Karis, A (Alar), Philipsen, J.N.J. (Sjaak), Marin, Marisol, Philipsen, Sjaak, Grosveld, Frank, Karis, Alar, Grosveld, F.G. (Frank)   +12 more
core   +2 more sources

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

The membrane curvature-inducing REEP1-4 proteins generate an ER-derived vesicular compartment

Nature Communications
The endoplasmic reticulum (ER) is shaped by abundant membrane curvature-generating proteins that include the REEP family member REEP5. The REEP1 subfamily, consisting of four proteins in mammals (REEP1-4), is less abundant and lack a N-terminal region ...
Yoko Shibata, Emily E. Mazur, Buyan Pan, Joao A. Paulo, Steven P. Gygi, Suyog Chavan, L. Sebastian Alexis Valerio, Jiuchun Zhang, Tom A. Rapoport   +8 more
doaj   +1 more source