Results 141 to 150 of about 14,507,937 (378)
Human organoids: a new dimension in cell biology
Molecular Biology of the Cell, 2019 Organoids derived from stem cells or tissues in culture can develop into structures that resemble the in vivo anatomy and physiology of intact organs. Human organoid cultures provide the potential to study human development and model disease processes ...
R. Lehmann +9 more
semanticscholar +1 more source
Cell biology, SevERing mitochondria
, 2011 The endoplasmic reticulum is an active participant in the division of another organelle, the ...
Lippincott-Schwarz, J., Rambold, A.
core +1 more source
Cyclic nucleotide signaling as a drug target in retinitis pigmentosa
FEBS Letters, EarlyView.Disruptions in cGMP and cAMP signaling can contribute to retinal dysfunction and photoreceptor loss in retinitis pigmentosa. This perspective examines the mechanisms and evaluates emerging evidence on targeting these pathways as a potential therapeutic strategy to slow or prevent retinal degeneration.
Katri Vainionpää +2 more
wiley +1 more source
TRAF2 binds to TIFA via a novel motif and contributes to its autophagic degradation
FEBS Letters, EarlyView.TRAF family members couple receptor signalling complexes to downstream outputs, but how they interact with these complexes is not always clear. Here, we show that during ADP‐heptose signalling, TRAF2 binding to TIFA requires two short sequence motifs in the C‐terminal tail of TIFA, which are distinct from the TRAF6 binding motif.
Tom Snelling +4 more
wiley +1 more source
mTORC2 regulates auditory hair cell structure and function
iScience, 2023 Summary: mTOR broadly controls cell growth, but little is known about the role of mTOR complex 2 (mTORC2) in the inner ear. To investigate the role of mTORC2 in sensory hair cells (HCs), we generated HC-specific Rictor knockout (HC-RicKO) mice.
Maurizio Cortada +3 more
doaj
SIMS imaging in neurobiology and cell biology
Journal of Analytical Atomic Spectrometry, 2019 Secondary ion mass spectrometry (SIMS) has been increasingly recognized as a powerful technique for visualizing molecular architectures in the fields of neurobiology and cell biology.
Paola Agüi-Gonzalez +2 more
semanticscholar +1 more source
Molecular Biology of the Cell, 2010 I came to cell biology from genetics because I found myself interested in understanding how things worked, not just why they worked. Although genetics is the most logical of all branches of biology, in the end, genes are merely placeholders for the complex choreography played out by the proteins, lipids, carbohydrates, and nucleic acids constituting a ...
openaire +4 more sources
FEBS Letters, EarlyView.Exposure to common noxious agents (1), including allergens, pollutants, and micro‐nanoplastics, can cause epithelial barrier damage (2) in our body's protective linings. This may trigger an immune response to our microbiome (3). The epithelial barrier theory explains how this process can lead to chronic noncommunicable diseases (4) affecting organs ...
Can Zeyneloglu +17 more
wiley +1 more source
Nonlinear brain dynamics as macroscopic manifestation of underlying many-body field dynamics [PDF]
, 2005 W. Freeman +9 more
semanticscholar +1 more source
FEBS Letters, EarlyView.Three‐dimensional (3D) biological systems have become key tools in lymphoma research, offering reliable in vitro and ex vivo platforms to explore pathogenesis and support precision medicine. This review highlights current 3D non‐Hodgkin lymphoma models, detailing their features, advantages, and limitations, and provides a broad perspective on future ...
Carla Faria +3 more
wiley +1 more source