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“Cell-Free Synthetic Biology”: Synthetic Biology Meets Cell-Free Protein Synthesis
Since Nirenberg and Matthaei used cell-free protein synthesis (CFPS) to elucidate the genetic code in the early 1960s [...]
Seok Hoon Hong
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Editorial, Seminars in Cell & Developmental Biology [PDF]
It is a pleasure to introduce this special edition of Cell and Development Biology dedicated to the field and application of Biosensors. This edition comprises seven reviews covering the most active research areas where we believe some of the most ...
Davis, Frank, Higson, Seamus P. J.
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Cell biology beyond the cell [PDF]
This issue of the JCB marks the start of a new series of reviews entitled “The Cell Biology of…”. The goal of this series is to elucidate the cell biology underlying complex physiological processes.
Tom Misteli, Priya Prakash Budde
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Future Needs in Mast Cell Biology. [PDF]
The pathophysiological roles of mast cells are still not fully understood, over 140 years since their description by Paul Ehrlich in 1878. Initial studies have attempted to identify distinct "subpopulations" of mast cells based on a relatively small ...
de Paulis, Amato+3 more
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Computational cell biology [PDF]
![Graphic][1] ©The New Yorker Collection from cartoonbank.com. All rights reserved. All of us who do experiments and think about biology on a daily basis know that biological systems are exceedingly complex.
Ira Mellman, Tom Misteli
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Cell Biology: Scaling and the Emergence of Evolutionary Cell Biology
A new study investigating the origins of diversity in the structure of the mitotic spindle in nematode embryos, at timescales spanning a few generations to hundreds of millions of years, finds that most features of the spindle evolve via a scaling relationship generated by natural selection acting directly upon embryo size.
Bruce Bowerman, Patrick C. Phillips
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The cell biology of vision [PDF]
Humans possess the remarkable ability to perceive color, shape, and motion, and to differentiate between light intensities varied by over nine orders of magnitude. Phototransduction—the process in which absorbed photons are converted into electrical responses—is the first stage of visual processing, and occurs in the outer segment, the light-sensing ...
Jen-Zen Chuang, Ching-Hwa Sung
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The cell biology of glycosphingolipids
Glycosphingolipids, a family of heterogeneous lipids with biophysical properties conserved from fungi to mammals, are key components of cellular membranes. Because of their tightly packed backbone, they have the ability to associate with other sphingolipids and cholesterol to form microdomains called lipid rafts, with which a variety of proteins ...
Degroote, S.+2 more
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Targeted gene silencing in human embryonic stem cells using cell-penetrating peptide PepFect 14
Background Human embryonic stem (hES) cells serve as an invaluable tool for research and future medicine, but their transfection often leads to unwanted side effects as the method itself may induce differentiation.
Egle-Helene Ervin+6 more
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Three facets of mathematical cancer biology research [PDF]
Cancer, as the uncontrollable cell growth, is related to many branches of biology. In this review, we will discuss three mathematical approaches for studying cancer biology: population dynamics, gene regulation, and developmental biology. If we understand all biochemical mechanisms of cancer cells, we can directly calculate how the cancer cell ...
arxiv