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Future Needs in Mast Cell Biology. [PDF]
The pathophysiological roles of mast cells are still not fully understood, over 140 years since their description by Paul Ehrlich in 1878. Initial studies have attempted to identify distinct "subpopulations" of mast cells based on a relatively small ...
de Paulis, Amato+3 more
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Computational cell biology [PDF]
![Graphic][1] ©The New Yorker Collection from cartoonbank.com. All rights reserved. All of us who do experiments and think about biology on a daily basis know that biological systems are exceedingly complex.
Ira Mellman, Tom Misteli
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“Cell-Free Synthetic Biology”: Synthetic Biology Meets Cell-Free Protein Synthesis
Since Nirenberg and Matthaei used cell-free protein synthesis (CFPS) to elucidate the genetic code in the early 1960s [...]
Seok Hoon Hong
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Cell Biology: Scaling and the Emergence of Evolutionary Cell Biology
A new study investigating the origins of diversity in the structure of the mitotic spindle in nematode embryos, at timescales spanning a few generations to hundreds of millions of years, finds that most features of the spindle evolve via a scaling relationship generated by natural selection acting directly upon embryo size.
Bruce Bowerman, Patrick C. Phillips
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The cell biology of vision [PDF]
Humans possess the remarkable ability to perceive color, shape, and motion, and to differentiate between light intensities varied by over nine orders of magnitude. Phototransduction—the process in which absorbed photons are converted into electrical responses—is the first stage of visual processing, and occurs in the outer segment, the light-sensing ...
Jen-Zen Chuang, Ching-Hwa Sung
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Targeted gene silencing in human embryonic stem cells using cell-penetrating peptide PepFect 14
Background Human embryonic stem (hES) cells serve as an invaluable tool for research and future medicine, but their transfection often leads to unwanted side effects as the method itself may induce differentiation.
Egle-Helene Ervin+6 more
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NaNog: A pluripotency homeobox (master) molecule. [PDF]
One of the most intriguing aspects of cell biology is the state of pluripotency, where the cell is capable of self-renewal for as many times as deemed necessary , then at a specified time can differentiate into any type of cell. This fundamental process
Aguib, YE+4 more
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The cell biology of glycosphingolipids
Glycosphingolipids, a family of heterogeneous lipids with biophysical properties conserved from fungi to mammals, are key components of cellular membranes. Because of their tightly packed backbone, they have the ability to associate with other sphingolipids and cholesterol to form microdomains called lipid rafts, with which a variety of proteins ...
Degroote, S.+2 more
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Three facets of mathematical cancer biology research [PDF]
Cancer, as the uncontrollable cell growth, is related to many branches of biology. In this review, we will discuss three mathematical approaches for studying cancer biology: population dynamics, gene regulation, and developmental biology. If we understand all biochemical mechanisms of cancer cells, we can directly calculate how the cancer cell ...
arxiv
Protocols for isolation and characterization of mouse placental hemogenic endothelial cells
Summary: The murine mid-gestational placenta has been identified as a hematopoietic site during embryonic development. Here, we describe a protocol for isolation and characterization of the hemogenic endothelial (HE) cells from mouse placenta.
Guixian Liang+3 more
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