Results 21 to 30 of about 3,538,937 (352)

Characterization of atherosclerotic plaques in blood vessels with low oxygenated blood and blood pressure (Pulmonary trunk): role of growth differentiation factor-15 (GDF-15)

open access: yesBMC Cardiovascular Disorders, 2021
Background Growth differentiation factor (GDF)-15 is linked to inflammation, cancer, and atherosclerosis. GDF-15 is expressed in most tissues but is extremely induced under pathological conditions. Elevated serum levels are suggested as a risk factor and
G. A. Bonaterra   +7 more
doaj   +1 more source

Myoneurin regulates BMP signaling by competing with Ppm1a for Smad binding

open access: yesiScience, 2022
Summary: A delicate balance of BMP activity is critical for tissue formation and organogenesis. However, the mechanical molecular details in ensuring the proper duration and intensity of BMP signaling have yet to be fully elucidated.
Shuyan Yang   +7 more
doaj   +1 more source

Administration of Vitamin D Metabolites Affects RNA Expression of Xenobiotic Metabolising Enzymes and Function of ABC Transporters in Rats [PDF]

open access: yes, 2019
From studies on different species and in cell culture systems, it has been suggested that vitamin D metabolites might affect themetabolism and elimination of xenobiotics.
Hansen, Kathrin   +7 more
core   +1 more source

Cell biology of molybdenum

open access: yesBiochimica et Biophysica Acta (BBA) - Molecular Cell Research, 2006
The transition element molybdenum (Mo) is of essential importance for (nearly) all biological systems as it is required by enzymes catalyzing diverse key reactions in the global carbon, sulfur and nitrogen metabolism. The metal itself is biologically inactive unless it is complexed by a special cofactor.
Ralf R. Mendel, Florian Bittner
openaire   +3 more sources

Human pluripotent stem cell-derived DDX4 and KRT-8 positive cells participate in ovarian follicle-like structure formation

open access: yesiScience, 2021
Summary: Understanding the mechanisms of human pluripotent stem cells (hPSCs) specification, development and differentiation to gametes are useful for elucidating the causes of infertility and potential treatment. This study aims to examine whether hPSCs
Danny C.W. Yu   +5 more
doaj   +1 more source

The cell biology of touch [PDF]

open access: yesJournal of Cell Biology, 2010
The sense of touch detects forces that bombard the body’s surface. In metazoans, an assortment of morphologically and functionally distinct mechanosensory cell types are tuned to selectively respond to diverse mechanical stimuli, such as vibration, stretch, and pressure.
Aislyn M. Nelson   +2 more
openaire   +3 more sources

“Cell-Free Synthetic Biology”: Synthetic Biology Meets Cell-Free Protein Synthesis

open access: yesMethods and Protocols, 2019
Since Nirenberg and Matthaei used cell-free protein synthesis (CFPS) to elucidate the genetic code in the early 1960s [...]
Seok Hoon Hong
doaj   +1 more source

Clathrin- and dynamin-dependent endocytosis limits canonical NF-κB signaling triggered by lymphotoxin β receptor

open access: yesCell Communication and Signaling, 2020
Background Lymphotoxin β receptor (LTβR) is a member of tumor necrosis factor receptor (TNFR) superfamily which regulates the immune response. At the cellular level, upon ligand binding, the receptor activates the pro-inflammatory NF-κB and AP-1 pathways.
Małgorzata Maksymowicz   +2 more
doaj   +1 more source

The cell biology of regeneration [PDF]

open access: yesJournal of Cell Biology, 2012
Regeneration of complex structures after injury requires dramatic changes in cellular behavior. Regenerating tissues initiate a program that includes diverse processes such as wound healing, cell death, dedifferentiation, and stem (or progenitor) cell proliferation; furthermore, newly regenerated tissues must integrate polarity and positional identity ...
Ryan S. King, Phillip A. Newmark
openaire   +3 more sources

GDF5 induces TBX3 in a concentration dependent manner - on a gold nanoparticle gradient

open access: yesHeliyon, 2020
Organs and tissues, such as cartilage and limbs, are formed during development through an orchestration of growth factors that function as morphogens.
L. Andreasson   +2 more
doaj   +1 more source

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