Results 41 to 50 of about 14,856,340 (397)
Background Plasmodium falciparum parasites cause malaria and co-exist in humans together with B-cells for long periods of time. Immunity is only achieved after repeated exposure.
Sreenivasulu B. Reddy +8 more
doaj +1 more source
Global parameter identification of stochastic reaction networks from single trajectories [PDF]
We consider the problem of inferring the unknown parameters of a stochastic biochemical network model from a single measured time-course of the concentration of some of the involved species.
A Auger +38 more
core +1 more source
ASPM promotes homologous recombination-mediated DNA repair by safeguarding BRCA1 stability
Summary: DNA double-strand break (DSB) repair by homologous recombination (HR) is essential for ensuring genome stability. Abnormal spindle-like microcephaly-associated (ASPM) gene encodes a spindle protein that is commonly implicated in primary ...
Shibin Xu +5 more
doaj +1 more source
Mesenchymal stem cell perspective: cell biology to clinical progress
The terms MSC and MSCs have become the preferred acronym to describe a cell and a cell population of multipotential stem/progenitor cells commonly referred to as mesenchymal stem cells, multipotential stromal cells, mesenchymal stromal cells, and ...
M. Pittenger +5 more
semanticscholar +1 more source
Systems cell biology melds high-throughput experimentation with quantitative analysis and modeling to understand many critical processes that contribute to cellular organization and dynamics. Recently, there have been several advances in technology and in the application of modeling approaches that enable the exploration of the dynamic properties of ...
Mast, Fred D. +2 more
openaire +3 more sources
Summary: The DNA-damage response is a complex signaling network that guards genomic integrity. The microtubule cytoskeleton is involved in the repair of DNA double-strand breaks; however, little is known about which cytoskeleton-related proteins are ...
Arlinda Dullovi +6 more
doaj +1 more source
SBML models and MathSBML [PDF]
MathSBML is an open-source, freely-downloadable Mathematica package that facilitates working with Systems Biology Markup Language (SBML) models. SBML is a toolneutral,computer-readable format for representing models of biochemical reaction networks ...
Shapiro, B.E. +9 more
core +2 more sources
Cells in the musculoskeletal system are subjected to various mechanical forces in vivo. Years of research have shown that these mechanical forces, including tension and compression, greatly influence various cellular functions such as gene expression ...
Wang James HC, Li Bin
doaj +1 more source
Myoneurin regulates BMP signaling by competing with Ppm1a for Smad binding
Summary: A delicate balance of BMP activity is critical for tissue formation and organogenesis. However, the mechanical molecular details in ensuring the proper duration and intensity of BMP signaling have yet to be fully elucidated.
Shuyan Yang +7 more
doaj +1 more source
Cell biology beyond the cell [PDF]
This issue of the JCB marks the start of a new series of reviews entitled “The Cell Biology of…”. The goal of this series is to elucidate the cell biology underlying complex physiological processes.
Budde, Priya Prakash, Misteli, Tom
openaire +2 more sources

