Results 41 to 50 of about 3,538,937 (352)

Mechanics rules cell biology

open access: yesSports Medicine, Arthroscopy, Rehabilitation, Therapy & Technology, 2010
Cells in the musculoskeletal system are subjected to various mechanical forces in vivo. Years of research have shown that these mechanical forces, including tension and compression, greatly influence various cellular functions such as gene expression ...
Wang James HC, Li Bin
doaj   +1 more source

Direct contact between Plasmodium falciparum and human B-cells in a novel co-culture increases parasite growth and affects B-cell growth

open access: yesMalaria Journal, 2021
Background Plasmodium falciparum parasites cause malaria and co-exist in humans together with B-cells for long periods of time. Immunity is only achieved after repeated exposure.
Sreenivasulu B. Reddy   +8 more
doaj   +1 more source

Centrosomal protein 120 promotes centrosome amplification and gastric cancer progression via USP54-mediated deubiquitination of PLK4

open access: yesiScience, 2023
Summary: Centrosomal protein 120 (CEP120) is a 120 kDa centrosome protein that plays an important role in centrosome replication. Overexpression of CEP120 can lead to centrosome duplicate abnormality, which is closely associated with tumorigenesis and ...
Chenggang Zhang   +11 more
doaj   +1 more source

mRNA splicing is modulated by intronic microRNAs

open access: yesiScience, 2023
Summary: Splicing of transcripts is catalyzed by the spliceosome, a mega-complex consisting of hundreds of proteins and five snRNAs, which employs direct interactions. When U1 snRNA forms high-affinity binding, namely more than eight base pairs, with the
Luba Farberov   +7 more
doaj   +1 more source

Computational cell biology [PDF]

open access: yesThe Journal of Cell Biology, 2003
![Graphic][1] ©The New Yorker Collection from cartoonbank.com. All rights reserved. All of us who do experiments and think about biology on a daily basis know that biological systems are exceedingly complex.
Ira Mellman, Tom Misteli
openaire   +3 more sources

The cell biology of vision [PDF]

open access: yesJournal of Cell Biology, 2010
Humans possess the remarkable ability to perceive color, shape, and motion, and to differentiate between light intensities varied by over nine orders of magnitude. Phototransduction—the process in which absorbed photons are converted into electrical responses—is the first stage of visual processing, and occurs in the outer segment, the light-sensing ...
Jen-Zen Chuang, Ching-Hwa Sung
openaire   +3 more sources

Identification of embryonic RNA granules that act as sites of mRNA translation after changing their physical properties

open access: yesiScience, 2022
Summary: Fertilized eggs begin to translate mRNAs at appropriate times and placements to control development, but how the translation is regulated remains unclear.
Keisuke Sato   +6 more
doaj   +1 more source

Give me a SINE: how Selective Inhibitors of Nuclear Export modulate autophagy and aging

open access: yesMolecular & Cellular Oncology, 2018
Autophagy is a cellular recycling process leading to lysosomal degradation of damaged macromolecules, which can protect cells against aging. The transcription factor EB (TFEB), a major transcriptional regulator of genes involved in autophagy and ...
A.V. Kumar   +5 more
doaj   +1 more source

Two dimensional electrophysiological characterization of human pluripotent stem cell-derived cardiomyocyte system. [PDF]

open access: yes, 2017
Stem cell-derived cardiomyocytes provide a promising tool for human developmental biology, regenerative therapies, disease modeling, and drug discovery.
Gimzewski, James K   +7 more
core   +2 more sources

Noise in multiple sclerosis: unwanted and necessary [PDF]

open access: yes, 2014
As our knowledge about the etiology of multiple sclerosis (MS) increases, deterministic paradigms appear insufficient to describe the pathogenesis of the disease, and the impression is that stochastic phenomena (i.e.
BORDI, Isabella   +7 more
core   +1 more source

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