Results 41 to 50 of about 1,625,351 (310)
The past decade has revealed the diversity and ubiquity of archaea in nature, with a growing number of studies highlighting their importance in ecology, biotechnology and even human health. Myriad lineages have been discovered, which expanded the phylogenetic breadth of archaea and revealed their central role in the evolutionary origins of eukaryotes ...
Marleen van Wolferen+4 more
openaire +3 more sources
Cell biology, SevERing mitochondria
The endoplasmic reticulum is an active participant in the division of another organelle, the ...
Lippincott-Schwarz, J., Rambold, A.
core +1 more source
Interactive learning in biology with PhotoCD and associated software [PDF]
This paper describes the pioneering development of flexible‐learning courseware in the teaching and learning of cell biology using a novel optical disk‐based technology — PhotoCD — and its associated computer software.
Baggott, Linda, Wright, Bruce
core +2 more sources
The cell biology of touch [PDF]
The sense of touch detects forces that bombard the body’s surface. In metazoans, an assortment of morphologically and functionally distinct mechanosensory cell types are tuned to selectively respond to diverse mechanical stimuli, such as vibration, stretch, and pressure.
Aislyn M. Nelson+2 more
openaire +3 more sources
Summary: Understanding the mechanisms of human pluripotent stem cells (hPSCs) specification, development and differentiation to gametes are useful for elucidating the causes of infertility and potential treatment. This study aims to examine whether hPSCs
Danny C.W. Yu+5 more
doaj
Administration of Vitamin D Metabolites Affects RNA Expression of Xenobiotic Metabolising Enzymes and Function of ABC Transporters in Rats [PDF]
From studies on different species and in cell culture systems, it has been suggested that vitamin D metabolites might affect themetabolism and elimination of xenobiotics.
Hansen, Kathrin+7 more
core +1 more source
CELL BIOLOGY AND SIGNALING [PDF]
The phylogenetically-conserved vertebrate transcription factor, NFIB, is an orchestrator of glial differentiation in the developing mammalian central nervous system. We found NFIB expression to be reduced in glioblastoma (GBM), the commonest and most lethal primary adult brain cancer, so investigated what effect increased expression of NFIB had on GBM.
M. Agarwal+200 more
openaire +4 more sources
ASPM promotes homologous recombination-mediated DNA repair by safeguarding BRCA1 stability
Summary: DNA double-strand break (DSB) repair by homologous recombination (HR) is essential for ensuring genome stability. Abnormal spindle-like microcephaly-associated (ASPM) gene encodes a spindle protein that is commonly implicated in primary ...
Shibin Xu+5 more
doaj
Cancer is becoming the leading cause of death all around the world. To develop better therapeutic options against cancer, we need a thorough understanding of tumor development and dissemination. As our knowledge increases, it becomes apparent that cancer
Serkan İsmail Göktuna+2 more
doaj +1 more source
The Cell Physiome: What do we need in a computational physiology framework for predicting single cell biology? [PDF]
Modern biology and biomedicine are undergoing a big-data explosion needing advanced computational algorithms to extract mechanistic insights on the physiological state of living cells. We present the motivation for the Cell Physiome: a framework and approach for creating, sharing, and using biophysics-based computational models of single cell ...
arxiv