Results 131 to 140 of about 1,708,738 (348)

Diffusion Spectrum Imaging Maps Early Axonal Loss and a Unique Progressive Signal in Neuronal Intranuclear Inclusion Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To delineate specific in vivo white matter pathology in neuronal intranuclear inclusion disease (NIID) using diffusion spectrum imaging (DSI) and define its clinical relevance. Methods DSI was performed on 42 NIID patients and 38 matched controls.
Kaiyan Jiang, Yixiu Pei, Xiaobao Hu, Ying Xiong, Fang Wang, Yanyan Yu, Min Zhu, Dandan Tan, Meihong Zhou, Daojun Hong, Fuqing Zhou   +10 more
wiley   +1 more source

Role of tunneling nanotubes in neuroglia

Neural Regeneration Research
Tunneling nanotubes are crucial structures for cellular communication and are observed in a variety of cell types. Glial cells, the most abundant cells in the nervous system, play a vital role in intercellular signaling and can show abnormal activation ...
Weichen Xu, Xingyu Yang, Hongmei Zheng, Changzheng Chen, Jiajia Yuan   +4 more
doaj   +1 more source

Structure–Function Decoupling of the Sensorimotor and Default Mode Networks in Black Americans With MS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Objectives Multiple sclerosis (MS) exhibits racially disparate rates of disease progression. Black people with MS (B‐PwMS) experience a more severe disease course than non‐Hispanic White people with MS (NHW‐PwMS). Here we investigated structural and functional connectivity as well as structure–function decoupling in the ...
Emilio Cipriano, Giacomo Boffa, Maria Petracca, Marta Ponzano, Nicole Graziano, Claire Wigley, Claire Riley, Jonathan Howard, Pietro Bontempi, Sylvia Klineova, Fred Lublin, Matilde Inglese   +11 more
wiley   +1 more source

A Prospective Study of Individuals at Risk of Multiple Sclerosis Informs the Design of Primary Prevention Studies

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective In multiple sclerosis, the optimal time for deploying a therapeutic intervention is before the central nervous system is damaged; given the success of trials treating the earliest stage of MS, the radiologically isolated syndrome, developing primary prevention strategies is an important next challenge.
Amy W. Laitinen, Ceren Tozlu, Tina Roostaei, Fatoumata Diallo, Kaho Onomichi, Jiyeon Son, Zongqi Xia, Philip L. De Jager   +7 more
wiley   +1 more source

Specificity of endothelial cells in endothelial dysfunction of diabetic kidney disease and their crosstalk with neighboring cells: an updated review

Frontiers in Endocrinology
Diabetic kidney disease (DKD), a major microvascular complication of diabetes, is characterized by persistent proteinuria, a declining glomerular filtration rate (GFR), and distinctive pathological alterations, often progressing to end-stage renal ...
Jiarui Li, Yue Zhang, Xiao Sun, Huifang Guan, Jingshuo Wang, Shuang Zhao, Chuanxi Tian, Mingda Han, Kaile Ma, Min Li   +9 more
doaj   +1 more source

Data from YAP Orchestrates Heterotypic Endothelial Cell Communication via HGF/c-MET Signaling in Liver Tumorigenesis

, 2023
Stefan Thomann, Sofia M.E. Weiler, Simone Marquard, Fabian Rose, Claudia R. Ball, Marcell Tóth, Teng Wei, Carsten Sticht, Sarah Fritzsche, Stéphanie Roessler, Carolina De La Torre, Eduard Ryschich, О. С. Ермакова, Carolin Mogler, Daniel Kazdal, Norbert Gretz, Hanno Glimm, Eugen Rempel, Peter Schirmacher, Kai Breuhahn   +19 more
openalex   +1 more source

Innate Immune Reprogramming Mediated by Endogenous Retroelement Dysregulation Drives Multiple Sclerosis Progression

Annals of Clinical and Translational Neurology, EarlyView.
Epigenetic reprogramming in hematopoietic stem and progenitor cells (HSPCs) and downstream myeloid cells, mediated by H3.3 downregulation and endogenous retroelement (ERE) overexpression, contributes to the progression of multiple sclerosis (MS). ABSTRACT Background Skewed myelopoiesis in the bone marrow has been identified as a key driver of multiple ...
Li‐Mei Xiao, Qiu‐Ping Zhao, Run‐Yun Li, Wei Chen, Huan‐Huan Song, Wan‐Jin Chen, Ying Fu   +6 more
wiley   +1 more source

Low-LET X-ray Radiation Enhances the Cellular Connectivity Through Tunneling Nanotubes in Glioblastoma Cells

Frontiers in Bioscience-Landmark
Background: Developing therapy resistance and exhibiting high invasiveness are significant challenges in treating aggressive cancers, such as glioblastoma, where intercellular communication plays a crucial role in cellular organization,
Nicole Matejka, Jessica Neubauer, Sarah Rudigkeit, Judith Reindl   +3 more
doaj   +1 more source

Multiscale Microstructure for Investigation of Cell–Cell Communication

, 2020
Ann‐Kathrin Schneider, Tim Scharnweber, Destiny Cammann, Bastian E. Rapp, Stefan Giselbrecht, Christof M. Niemeyer   +5 more
openalex   +1 more source

Prevascularization techniques for dental pulp regeneration: potential cell sources, intercellular communication and construction strategies [PDF]

, 2023
Qiao Ruan, Shenglong Tan, Li Guo, Dandan Ma, Jun Wen   +4 more
openalex   +1 more source