Results 11 to 20 of about 595,345 (267)

Dissecting Immunosuppressive Cell Communication Patterns Reveals JunB Proto-Oncogene (JUNB) Shaping a Non-Inflamed Tumor Microenvironment

Frontiers in Genetics, 2022
Background: Immunosuppressive cell interactions are responsible for tumor progression and metastasis, as well as anti-tumor immune dysfunction. However, the communication pattern remains unclear.Methods: We first integrated two single-cell RNA-seq ...
Hualin Chen, Gang Chen
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Synchronization of oscillatory growth prepares fungal hyphae for fusion

eLife, 2023
Communication is crucial for organismic interactions, from bacteria, to fungi, to humans. Humans may use the visual sense to monitor the environment before starting acoustic interactions.
Valentin Wernet, Marius Kriegler, Vojtech Kumpost, Ralf Mikut, Lennart Hilbert, Reinhard Fischer   +5 more
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Docosahexaenoic fatty acid reduces the pro‐inflammatory response induced by IL-1β in astrocytes through inhibition of NF-κB and AP-1 transcription factor activation

BMC Neuroscience, 2021
Background Astrocytes are responsible for a broad range of functions that maintain homeostasis in the brain. However, their response to the pro-inflammatory cytokines released by activated microglia in various neurological pathologies may exacerbate ...
Emilia Zgórzyńska, Dawid Stulczewski, Barbara Dziedzic, Kuan-Pin Su, Anna Walczewska   +4 more
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Exosome-Mediated Therapeutic Strategies for Management of Solid and Hematological Malignancies

Cells, 2022
Exosomes are small membrane vesicles of endocytic origin containing cytokines, RNAs, growth factors, proteins, lipids, and metabolites. They have been identified as fundamental intercellular communication controllers in several diseases and an enormous ...
Alessandro Allegra, Claudia Petrarca, Mario Di Gioacchino, Marco Casciaro, Caterina Musolino, Sebastiano Gangemi   +5 more
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Exosomes: Emerging Cell-Free Based Therapeutics in Dermatologic Diseases

Frontiers in Cell and Developmental Biology, 2021
Exosomes are lipid bilayer vesicles released by multiple cell types. These bioactive vesicles are gradually becoming a leading star in intercellular communication involving in various pathological and physiological process.
Hui Shi, Min Wang, Yaoxiang Sun, Dakai Yang, Wenrong Xu, Hui Qian   +5 more
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Fibrin, Bone Marrow Cells and Macrophages Interactively Modulate Cardiomyoblast Fate

Biomedicines, 2022
Interactions between macrophages, cardiac cells and the extracellular matrix are crucial for cardiac repair following myocardial infarction (MI). We hypothesized that cell-based treatments might modulate these interactions.
Inês Borrego, Aurélien Frobert, Guillaume Ajalbert, Jérémy Valentin, Cyrielle Kaltenrieder, Benoît Fellay, Michael Stumpe, Stéphane Cook, Joern Dengjel, Marie-Noëlle Giraud   +9 more
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Single-cell analysis reveals melanocytes may promote inflammation in chronic wounds through cathepsin G

Frontiers in Genetics, 2023
During acute wound (AW) healing, a series of proper communications will occur between different epidermal cells at precise temporal stages to restore the integrity of the skin.
Aobuliaximu Yakupu, Aobuliaximu Yakupu, Di Zhang, Di Zhang, Haonan Guan, Haonan Guan, Minfei Jiang, Minfei Jiang, Jiaoyun Dong, Jiaoyun Dong, Yiwen Niu, Yiwen Niu, Jiajun Tang, Jiajun Tang, Yingkai Liu, Yingkai Liu, Xian Ma, Xian Ma, Shuliang Lu, Shuliang Lu   +19 more
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Inflammasome‐induced extracellular vesicles harbour distinct RNA signatures and alter bystander macrophage responses

Journal of Extracellular Vesicles, 2021
Infectious organisms and damage of cells can activate inflammasomes, which mediate tissue inflammation and adaptive immunity. These mechanisms evolved to curb the spread of microbes and to induce repair of the damaged tissue.
Christina F. Budden, Linden J. Gearing, Romina Kaiser, Lena Standke, Paul J. Hertzog, Eicke Latz   +5 more
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The Role of Exosomes in the Pathophysiology of Chronic Rhinosinusitis

Frontiers in Cellular and Infection Microbiology, 2022
Non-invasive biomarker analysis has made repetitive and painless sampling over time possible. Exosomes are being released from a parent cell and their cargo mirrors the cell micromilieu of the parent cell. Therefore, exosomes are promising surrogates for
Sarina K. Mueller
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Roles of the m6A Modification of RNA in the Glioblastoma Microenvironment as Revealed by Single-Cell Analyses

Frontiers in Immunology, 2022
PurposeGlioblastoma multiforme (GBM) is a common and aggressive form of brain tumor. The N6-methyladenosine (m6A) mRNA modification plays multiple roles in many biological processes and disease states.
Feng Yuan, Xiangming Cai, Zixiang Cong, Yingshuai Wang, Yuanming Geng, Yiliyaer Aili, Chaonan Du, Junhao Zhu, Jin Yang, Chao Tang, Aifeng Zhang, Aifeng Zhang, Sheng Zhao, Sheng Zhao, Sheng Zhao, Chiyuan Ma, Chiyuan Ma, Chiyuan Ma, Chiyuan Ma, Chiyuan Ma   +19 more
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