Results 11 to 20 of about 599,411 (264)
Frontiers in Aging Neuroscience, 2022 Monocytes have been reported to be important mediators of the protective effect of exercise against the development of Alzheimer’s disease (AD). This study aims explored the mechanism by which monocytes achieve this.
Yisheng Chen +14 more
doaj +1 more source
Tumor Necrosis Factor Alpha Signaling and Organogenesis
Frontiers in Cell and Developmental Biology, 2021 Tumor necrosis factor alpha (TNF-α) plays important roles in processes such as immunomodulation, fever, inflammatory response, inhibition of tumor formation, and inhibition of viral replication.
Kai You +4 more
doaj +1 more source
Midkine Prevents Calcification of Aortic Valve Interstitial Cells via Intercellular Crosstalk
Frontiers in Cell and Developmental Biology, 2021 Calcified aortic valve disease (CAVD), the most common valvular heart disease, lacks pharmaceutical treatment options because its pathogenesis remains unclear.
Qian Zhou +20 more
doaj +1 more source
Multiplexing cell-cell communication
Molecular Systems Biology, 2019 AbstractThe engineering of advanced multicellular behaviors, such as the programmed growth of biofilms or tissues, requires cells to communicate multiple aspects of physiological information. Unfortunately, few cell-cell communication systems have been developed for synthetic biology. Here, we engineer a genetically-encoded channel selector device that
John T Sexton, Jeffrey J Tabor
openaire +4 more sources
Frontiers in Aging Neuroscience, 2023 IntroductionStem cells are a promising therapeutic in Alzheimer’s disease (AD) given the complex pathophysiologic pathways involved. However, the therapeutic mechanisms of stem cells remain unclear.
Kevin S. Chen +19 more
doaj +1 more source
Frontiers in Genetics, 2022 Background: Immunosuppressive cell interactions are responsible for tumor progression and metastasis, as well as anti-tumor immune dysfunction. However, the communication pattern remains unclear.Methods: We first integrated two single-cell RNA-seq ...
Hualin Chen, Gang Chen
doaj +1 more source
Synchronization of oscillatory growth prepares fungal hyphae for fusion
eLife, 2023 Communication is crucial for organismic interactions, from bacteria, to fungi, to humans. Humans may use the visual sense to monitor the environment before starting acoustic interactions.
Valentin Wernet +5 more
doaj +1 more source
Exosome-Mediated Therapeutic Strategies for Management of Solid and Hematological Malignancies
Cells, 2022 Exosomes are small membrane vesicles of endocytic origin containing cytokines, RNAs, growth factors, proteins, lipids, and metabolites. They have been identified as fundamental intercellular communication controllers in several diseases and an enormous ...
Alessandro Allegra +5 more
doaj +1 more source
Exosomes: Emerging Cell-Free Based Therapeutics in Dermatologic Diseases
Frontiers in Cell and Developmental Biology, 2021 Exosomes are lipid bilayer vesicles released by multiple cell types. These bioactive vesicles are gradually becoming a leading star in intercellular communication involving in various pathological and physiological process.
Hui Shi +5 more
doaj +1 more source
Fibrin, Bone Marrow Cells and Macrophages Interactively Modulate Cardiomyoblast Fate
Biomedicines, 2022 Interactions between macrophages, cardiac cells and the extracellular matrix are crucial for cardiac repair following myocardial infarction (MI). We hypothesized that cell-based treatments might modulate these interactions.
Inês Borrego +9 more
doaj +1 more source