Results 41 to 50 of about 13,173,007 (100)

Extracellular Vesicles from Adipose Tissue Could Promote Metabolic Adaptation through PI3K/Akt/mTOR

open access: yesCells, 2022
Extracellular vesicles (EVs) are nanoparticles secreted by cells under physiological and pathological conditions, such as metabolic diseases. In this context, EVs are considered potential key mediators in the physiopathology of obesity.
Jaime Delgadillo-Velázquez   +3 more
doaj   +1 more source

Predicting cell-to-cell communication networks using NATMI

open access: yesNature Communications, 2020
Development of high throughput single-cell sequencing technologies has made it cost-effective to profile thousands of cells from diverse samples containing multiple cell types. To study how these different cell types work together, here we develop NATMI (
Rui Hou   +4 more
semanticscholar   +1 more source

Applications and analytical tools of cell communication based on ligand-receptor interactions at single cell level

open access: yesCell & Bioscience, 2021
Cellular communication is an essential feature of multicellular organisms. Binding of ligands to their homologous receptors, which activate specific cell signaling pathways, is a basic type of cellular communication and intimately linked to many ...
Fen Ma   +5 more
semanticscholar   +1 more source

Role of Extracellular Vesicles in Autoimmune Pathogenesis

open access: yesFrontiers in Immunology, 2020
Autoimmune diseases are conditions that emerge from abnormal immune responses to natural parts of the body. Extracellular vesicles (EVs) are membranous structures found in almost all types of cells.
Wen-Cheng Wu   +3 more
doaj   +1 more source

New avenues for systematically inferring cell-cell communication: through single-cell transcriptomics data

open access: yesProtein & Cell, 2020
For multicellular organisms, cell-cell communication is essential to numerous biological processes. Drawing upon the latest development of single-cell RNA-sequencing (scRNA-seq), high-resolution transcriptomic data have deepened our understanding of ...
Xin Shao   +4 more
semanticscholar   +1 more source

Routes and mechanisms of extracellular vesicle uptake

open access: yesJournal of Extracellular Vesicles, 2014
Extracellular vesicles (EVs) are small vesicles released by donor cells that can be taken up by recipient cells. Despite their discovery decades ago, it has only recently become apparent that EVs play an important role in cell-to-cell communication.
Laura Ann Mulcahy   +2 more
doaj   +1 more source

Modeling Cell Communication in Cancer With Organoids: Making the Complex Simple

open access: yesFrontiers in Cell and Developmental Biology, 2020
Homotypic and heterotypic interactions between cells are of crucial importance in multicellular organisms for the maintenance of physiological functions.
E. Fiorini, L. Veghini, V. Corbo
semanticscholar   +1 more source

Bioinspired Extracellular Vesicles: Lessons Learned From Nature for Biomedicine and Bioengineering

open access: yesNanomaterials, 2020
Efficient communication is essential in all layers of the biological chain. Cells exchange information using a variety of signaling moieties, such as small molecules, proteins, and nucleic acids.
Assaf Zinger   +8 more
doaj   +1 more source

Midkine Prevents Calcification of Aortic Valve Interstitial Cells via Intercellular Crosstalk

open access: yesFrontiers in Cell and Developmental Biology, 2021
Calcified aortic valve disease (CAVD), the most common valvular heart disease, lacks pharmaceutical treatment options because its pathogenesis remains unclear.
Qian Zhou   +20 more
doaj   +1 more source

Exosomes Regulate Interclonal Communication on Osteogenic Differentiation Among Heterogeneous Osteogenic Single-Cell Clones Through PINK1/Parkin-Mediated Mitophagy

open access: yesFrontiers in Cell and Developmental Biology, 2021
Mesenchymal stem cells (MSCs) are intrinsically heterogeneous and are comprised of distinct subpopulations that differ in their differentiation potential.
Dongdong Fei   +11 more
doaj   +1 more source

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