Results 91 to 100 of about 10,810 (302)

Cellular compartmentation of zinc in leaves of the hyperaccumulator Thlaspi caerulescens

, 1999
Cellular compartmentation of Zn in the leaves of the hyperaccumulator Thlaspi caerulescens was investigated using energydispersive x-ray microanalysis and single-cell sap extraction.
Zhao, Fang Jie, Zhao, F-J., McGrath, Steve P., McGrath, S. P., Küpper, Hendrik, Kupper, H.   +5 more
core   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Compartmentation protects trypanosomes from the dangerous design of glycolysis

, 2000
Unlike in other organisms, in trypanosomes and other Kinetoplastida the larger part of glycolysis takes place in a specialized organelle, called the glycosome, At present it is impossible to remove the glycosome without changing much of the rest of the ...
Mensonides, FIC, Bakker, BM, van Hoek, P, Westerhoff, HV, Teusink, B, Mensonides, F.I.C., Michels, P.A.M., Michels, Paul A. M., Westerhoff, H.V., Bakker, B.M., Westerhoff, H.V.; id_orcid, Teusink, B., van Hoek, P.   +12 more
core   +1 more source

Intracellular product recycling in high succinic acid producing yeast at low pH

Microbial Cell Factories, 2017
Background The metabolic engineering of Saccharomyces cerevisiae for the production of succinic acid has progressed dramatically, and a series of high-producing hosts are available.
S. Aljoscha Wahl, Cristina Bernal Martinez, Zheng Zhao, Walter M. van Gulik, Mickel L. A. Jansen   +4 more
doaj   +1 more source

Beta-catenin phosphorylated at threonine 120 antagonizes generation of active beta-catenin by spatial localization in trans-Golgi network. [PDF]

PLoS ONE, 2012
The stability and subcellular localization of beta-catenin, a protein that plays a major role in cell adhesion and proliferation, is tightly regulated by multiple signaling pathways. While aberrant activation of beta-catenin signaling has been implicated
Cheng Du, Chuanyou Zhang, Zhuo Li, Md Helal Uddin Biswas, K C Balaji   +4 more
doaj   +1 more source

Phosphoinositides and inositol phosphates as molecular glues

FEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry, Alexander J. Cutright, Mong Na Claire Loi, Jessica Martin, Joseph W. Gilligan, Jakub N. Kubina, Michael J. Arambula, Susanna Tanada Palmu, Daniella Zhou, Raymond D. Blind   +9 more
wiley   +1 more source

Intracellular compartmentation of CTP synthase in Drosophila.

, 2010
Compartmentation is essential for the localization of biological processes within a eukaryotic cell. ATP synthase localizes to organelles such as mitochondria and chloroplasts.
Liu, Ji-Long, Liu, JL, Ji-Long Liu
core   +1 more source

α‐Synuclein aggregation landscape from phase separation to neurotoxic intermediates

FEBS Letters, EarlyView.
Alpha‐synuclein aggregation in Parkinson's disease involves a complex landscape of transient intermediates, including oligomers, fibrils and liquid–liquid phase separation (LLPS). A view is emerging in which LLPS maturation into solid‐like condensates may contribute to the formation of neurotoxic species.
Silvia Arino, Giuliana Fusco, Alfonso De Simone   +2 more
wiley   +1 more source

Visualization of Protein Compartmentation within the Plasma Membrane of Living Yeast Cells

, 2003
Different distribution patterns of the arginine/H+ symporter Can1p, the H+ plasma membrane ATPase Pma1p, and the hexose transport facilitator Hxt1p within the plasma membrane of living Saccharomyces cerevisiae cells were visualized using fluorescence ...
Widmar Tanner, Malínský, Jan, Jan Malínský, Tanner, Widmar, Katerina Malínská, Miroslava Opekarová, Malínská, Katerina, Opekarová, Miroslava   +7 more
core   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source