Results 61 to 70 of about 10,810 (302)

Autonomous spheroid formation by culture plate compartmentation

open access: yes, 2021
Scaffold-free 3D cell cultures (e.g. pellet cultures) are widely used in medical science, including cartilage regeneration. Their drawbacks are high time/reagent consumption and lack of early readout parameters.
Nürnberger, Sylvia; orcid:   +3 more
core   +1 more source

Hydrogen sulfide: a new endogenous player in an old mechanism of plant tolerance to high salinity

open access: yesActa Botânica Brasílica, 2017
High salinity affects plants due to stimulation of osmotic stress. Cell signaling triggered by nitric oxide (NO) and hydrogen sulfide (H2S) activates a cascade of biochemical events that culminate in plant tolerance to abiotic and biotic stresses.
Cristiane J. da-Silva, Luzia V. Modolo
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Plasma membrane compartmentation in Saccharomyces cerevisiae

open access: yes, 2009
In the plasma membrane of cells the complex variety of components is sorted into subcompartments, microdomains and nanoclusters. We only begin to understand the principles of this higher order.
Großmann, Guido
core   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Silicon Differently Affects Apoplastic Binding of Excess Boron in Wheat and Sunflower Leaves

open access: yesPlants, 2023
Monocots and dicots differ in their boron (B) requirement, but also in their capacity to accumulate silicon (Si). Although an ameliorative effect of Si on B toxicity has been reported in various crops, differences among monocots and dicots are not clear,
Jasna Savic   +6 more
doaj   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Silicon facilitates manganese phytoextraction by cucumber (Cucumis sativus L.)

open access: yesZaštita Materijala, 2016
The effect of excess nutrient levels of manganese (Mn, 50 and 100 mM) on the growth inhibition and the appearance of Mn-toxicity symptoms in the leaves was studied in cucumber plants (Cucumis sativus L. cv. Chinese long). Silicon (Si), when supplied as 1.
Vuk Maksimović, Miloš Mojović
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Plants strategies against metal phytotoxicity as a key prerequisite for an effective phytoremediation: Cellular mechanisms: Part I

open access: yesZaštita Materijala, 2014
The tolerance of plants to metal stress is the key prerequisite for an effective phytoremediation. Numerous biochemical reactions occur in plants under metal stress, so those plants with better ability to adjust to the toxicity effects are able to ...
Slađana Č. Alagić
doaj   +1 more source

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