Results 121 to 130 of about 17,041,985 (363)
Three‐dimensional cell culture model utilization in cancer stem cell research
Three‐dimensional (3D) cell culture models are becoming increasingly popular in contemporary cancer research and drug resistance studies. Recently, scientists have begun incorporating cancer stem cells (CSCs) into 3D models and modifying culture ...
Z. Bielecka +4 more
semanticscholar +1 more source
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Low Cost, Adhesion Strength Based Cell Sorter [PDF]
In many in vitro experiments, primary cells are harvested from an animal species to undergo experimental manipulation and subsequent analysis. Cell sorters are a luxury to have after cell harvesting to ensure pure populations of cells.
Burtch, Emily +3 more
core +2 more sources
Two dimensional electrophysiological characterization of human pluripotent stem cell-derived cardiomyocyte system. [PDF]
Stem cell-derived cardiomyocytes provide a promising tool for human developmental biology, regenerative therapies, disease modeling, and drug discovery.
Gimzewski, James K +7 more
core +2 more sources
Fetal Bovine Serum RNA Interferes with the Cell Culture derived Extracellular RNA
Fetal bovine serum (FBS) has been used in eukaryotic cell cultures for decades. However, little attention has been paid to the biological effects associated with RNA content of FBS on cell cultures.
Zhiyun Wei +3 more
semanticscholar +1 more source
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser +11 more
wiley +1 more source
Bioreactor-Based Liquid Culture and Production of Konjac Micro-Corm
Konjac (Amorphophallus konjac K. Koch) has numerous health benefits, but traditional propagation is hindered by long growth periods and soil-borne diseases. This study developed a novel cell liquid culture system to directly produce micro-corms of konjac
Yuqi Sun +5 more
doaj +1 more source
Ultraviolet microscopy aids in cytological and biomedical research [PDF]
Ultraviolet microscopy is used by cytologists and biochemists to study the morphological and physiological changes in the living cell under varied culture conditions.
Schlenk, F., Svihla, B.
core +1 more source
Culture conditions influence satellite cell activation and survival of single myofibers [PDF]
Single myofiber isolation protocols allow to obtain an in vitro system in which the physical association between the myofiber and its stem cells, the satellite cells, is adequately preserved.
Adamo, Sergio +5 more
core +2 more sources
Comprehensive analysis of genomic mutations, gene expression, DNA methylation, and pathway analysis of TCGA data was carried out to define cancer types in which proteasome subunits expression is associated with worse survival. Albeit the effect of specific proteasome subunits on cellular function, the main role of the proteasome is better evaluated ...
Ruba Al‐Abdulla +5 more
wiley +1 more source

