Results 71 to 80 of about 3,334,633 (288)
Metabolomics guides rational development of a simplified cell culture medium for drug screening against Trypanosoma brucei [PDF]
, 2013 n vitro culture methods underpin many experimental approaches to biology and drug discovery. The modification of established cell culture methods to make them more biologically relevant or to optimize growth is traditionally a laborious task.
Alsford +58 more
core +2 more sources
FEBS Letters, EarlyView.Low‐density lipoprotein receptor‐related protein 6 (LRP6) is a key receptor for the Wnt antagonist Dickkopf1 (DKK1). DKK1 protein expression is induced in a bleomycin (BLM)‐induced lung injury model. We show that DKK1 induces proinflammatory and profibrotic genes in lung fibroblasts.
Eun‐Ah Sung +6 more
wiley +1 more source
Stem Cell Research & Therapy, 2018 Mesenchymal stem cell therapy is a promising treatment for perianal Crohn’s fistulas refractory to conventional therapy, which are an extremely morbid complication and a true therapeutic challenge.
Cécile Philandrianos +12 more
doaj +1 more source
Consequences of simulated microgravity in neural stem cells: biological effects and metabolic response. [PDF]
, 2015 Objective: Microgravity was often shown to cause cell damage and impair cell cycle in a variety of biological systems. Since the effects on the neural system were poorly investigated, we aimed to gain insight into how biological processes such as cell ...
ABBALLE, LUANA +15 more
core +1 more source
FEBS Letters, EarlyView.We present the first solution structure of the Ca2+‐depleted LETM1 F‐EF‐hand through a D676A/N678A Ca2+ binding‐deficient mutant, revealing a closed hydrophobic cleft caused by a unique F1‐helix pivot. The apo LETM1 F‐EF‐hand exhibits regiospecific hot and cold unfolding, sensitivity to physiological pH changes and potential for promiscuous heterotypic
Qi‐Tong Lin +2 more
wiley +1 more source
Experimental Investigation of Distant Cellular Interaction among Adipose Derived Stem-Cells [PDF]
arXiv, 2014 In addition to chemical and mechanical interactions between cells electromagnetic field produced by cells has been considered as another form of signaling for cell-cell communication. The aim of this study is evaluation of electromagnetic effects on viability of Adipose-derived stem cells (ADSCs) without co-culturing.
arxiv
High-throughput design of cultured tissue moulds using a biophysical model [PDF]
arXiv, 2023 The technique presented here identifies tethered mould designs, optimised for growing cultured tissue with very highly-aligned cells. It is based on a microscopic biophysical model for polarised cellular hydrogels. There is an unmet need for tools to assist mould and scaffold designs for the growth of cultured tissues with bespoke cell organisations ...
arxiv
Cell cycle analysis of primary sponge cell cultures [PDF]
, 2011 Proliferation of sponge cells is generally measured via cell counts or viability assays. However, more insight into the proliferative state of a sponge cell population can be obtained from the distribution of the cells over the different phases of the ...
Martens, D.E. +3 more
core +3 more sources
Taurine promotes glucagon‐like peptide‐1 secretion in enteroendocrine L cells
FEBS Letters, EarlyView.Taurine, a sulfur‐containing amino acid, is likely taken up by enteroendocrine L cells via the taurine transporter. This process increases the levels of cytosolic ATP. The increase in intracellular Ca2+ concentrations and glucagon‐like peptide‐1 secretion through membrane depolarization is caused by the closure of ATP‐sensitive potassium channels ...
Yuri Osuga +6 more
wiley +1 more source
Research in Molecular Medicine, 2020 Background: Cell viability and apoptosis are two crucial factors that may determine cell fate. There are several factors, such as hypoxia, which may be effective in cell processes.
Naser Kalhor Qom +2 more
doaj