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Is It Time to Start Transitioning From 2D to 3D Cell Culture?
Cell culture is an important and necessary process in drug discovery, cancer research, as well as stem cell study. Most cells are currently cultured using two-dimensional (2D) methods but new and improved methods that implement three-dimensional (3D ...
Caleb Jensen +5 more
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Undergraduate students learn about mammalian cell culture applications in introductory biology courses. However, laboratory modules are rarely designed to provide hands-on experience with mammalian cells or teach cell culture techniques, such as ...
Kristen Bowey-Dellinger +12 more
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Experimental liver models: From cell culture techniques to microfluidic organs‐on‐chip [PDF]
The liver is one of the most studied organs of the human body owing to its central role in xenobiotic and drug metabolism. In recent decades, extensive research has aimed at developing in vitro liver models able to mimic liver functions to study ...
Michela Anna Polidoro +4 more
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Article on cell culture techniques [PDF]
Viswabramhana Indhu, PT Nagaraju
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Biomimetic Scaffolds-A Novel Approach to Three Dimensional Cell Culture Techniques for Potential Implementation in Tissue Engineering. [PDF]
Biomimetic scaffolds imitate native tissue and can take a multidimensional form. They are biocompatible and can influence cellular metabolism, making them attractive bioengineering platforms. The use of biomimetic scaffolds adds complexity to traditional
Górnicki T +14 more
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Advanced 3D Cell Culture Techniques in Micro-Bioreactors, Part II: Systems and Applications [PDF]
In this second part of our systematic review on the research area of 3D cell culture in micro-bioreactors we give a detailed description of the published work with regard to the existing micro-bioreactor types and their applications, and highlight ...
Brigitte Altmann +3 more
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3D Cardiac Cell Culture: A Critical Review of Current Technologies and Applications
Three-dimensional (3D) cell culture is often mentioned in the context of regenerative medicine, for example, for the replacement of ischemic myocardium with tissue-engineered muscle constructs.
Christian Zuppinger
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Implications of Three-Dimensional Cell Culture in Cancer Therapeutic Research
Replicating the naturalistic biomechanical milieu of cells is a primary requisite to uncover the fundamental life processes. The native milieu is significantly not replicated in the two-dimensional (2D) cell cultures.
Kolluri Poornima +11 more
semanticscholar +1 more source
Bioreactors have proven useful for a vast amount of applications. Besides classical large-scale bioreactors and fermenters for prokaryotic and eukaryotic organisms, micro-bioreactors, as specialized bioreactor systems, have become an invaluable tool for ...
C. Grün, B. Altmann, E. Gottwald
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Skeletal reconstruction is necessary in cases of bone defects created by tumors, trauma, and abnormalities. Regeneration of bone defects remains a critical problem, and current approaches are based on biocompatible scaffolds. Spheroids represent a simple
Iñigo Gaitán-Salvatella +4 more
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