Results 11 to 20 of about 555,194 (267)
Van Tıp Dergisi, 2022 INTRODUCTION: Glioblastoma multiforme (GBM) is one of the most common and deadliest primary brain tumors. Despite standard treatments such as surgical resection, radiation, and high-dose chemotherapy, the average survival time of patients after diagnosis
Mehmet Eşref Alkış
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Is It Time to Start Transitioning From 2D to 3D Cell Culture?
Frontiers in Molecular Biosciences, 2020 Cell culture is an important and necessary process in drug discovery, cancer research, as well as stem cell study. Most cells are currently cultured using two-dimensional (2D) methods but new and improved methods that implement three-dimensional (3D ...
Caleb Jensen +5 more
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Dental Research Journal, 2021 Background: Squamous cell carcinoma (SCC) is the most common oral malignancy with high rate of mortality. Cisplatin, as the most effective chemotherapy drug, has side effects.
Fatima Bijani +5 more
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Cells, 2022 Inadequacy of most animal models for drug efficacy assessments has led to the development of improved in vitro models capable of mimicking in vivo exposure scenarios.
Hadi Hashemzadeh +5 more
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Optimized Primary Culture and Subculture of Granulosa Cells
Pharmaceutical and Biomedical Research, 2022 Background: Primordial follicle includes an oocyte surrounded by a layer of somatic cells called Granulosa Cells (GCs). GCs, also known as nurse cells, are an important protective element for the growth and survival of oocytes.
Nadia Fallah +4 more
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An Modified Primary Culture Method of Breast Cancer-associated Fibroblasts
Zhongliu Fangzhi Yanjiu, 2018 Objective To establish a rapid and high efficient method of primary culture of BCAFs by improving primary culture methods of common breast cancer-associated fibroblasts (BCAFs).
LI Zhiyong, BAI Xue, CAI Huiyun
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Evaluation of a composite skin substitute to treat venous stasis ulcers: a pilot study
Brazilian Journal of Transplantation, 2006 Introduction: Venous leg ulcers represent a therapeutic challenge, and they are associated to significant morbidity and cost. Many advances have been made to develop and apply biological skin substitutes, showing they can be beneficial for patients with
Paula Dadalti-Granja +7 more
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Memantine protects the cultured rat hippocampal neurons treated by NMDA and amyloid β1–42
Frontiers in Neuroscience, 2023 Alzheimer’s disease (AD) is a devastating neurodegenerative condition with no effective treatments. Recent research highlights the role of NMDA receptors in AD development, as excessive activation of these receptors triggers excitotoxicity. Memantine, an
Nataliia M. Rozumna +2 more
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Bioengineering, 2020 Human embryonic stem cell-derived mesenchymal progenitor (hES-MP) cells are mesenchymal-like cells, derived from human embryonic stem cells without the aid of feeder cells. They have been suggested as a potential alternative to mesenchymal stromal cells (
Sandra M. Jonsdottir-Buch +2 more
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, 2009 Different sources of hepatic tissue, including whole or split livers from organ donors or from cadavers, waste liver from therapeutic hepatectomies or small-sized surgical biopsies, can be successfully used to prepare human hepatocytes cultures.
Castell, Jose V +1 more
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