Advances and drawbacks of the adaptation to serum-free culture of CHO-K1 cells for monoclonal antibody production [PDF]
, 2013 Currently, mammalian cell technology has become the focus of biopharmaceutical production, with strict regulatory scrutiny of the techniques employed.
Azeredo, Joana +6 more
core +1 more source
Molecular Oncology, EarlyView.Cancer stem cells are associated with aggressive disease, but a deep characterization of such markers is lacking in endometrial cancer. This study uses imaging mass cytometry to explore putative cancer stem cell markers in endometrial tumors and corresponding organoid models.
Hilde E. Lien +7 more
wiley +1 more source
Growth factor involvement in tension-induced skeletal muscle growth [PDF]
New muscle tissue culture techniques were developed to grow embryonic skeletal myofibers which are able to differentiate into more adultlike myofibers. Studies on mechanical simulation of cultured muscle cell growth will now be more directly applicable ...
Vandenburgh, Herman W.
core +1 more source
Strictosidine, the common precursor for monoterpenoid indole alkaloids with 3 α and 3 β configuration [PDF]
, 1978 Recently we reported that strictosidine (l> is the key intermediate in the formation of the three classes (ASDidOf3DeIm5, Iboga, Corynanthe) of monoterpenoid indole alkaloids In Catharanthus roseus and a variety of other plant species in cell culture ...
Battersby +13 more
core +1 more source
Galactosylation of rat natural scaffold for MSC differentiation into hepatocyte-like cells: A comparative analysis of 2D vs. 3D cell culture techniques. [PDF]
Biochem Biophys Rep, 2023 Vazirzadeh M +3 more
europepmc +1 more source
Peripheral blood proteome biomarkers distinguish immunosuppressive features of cancer progression
Molecular Oncology, EarlyView.Immune status significantly influences cancer progression. This study used plasma proteomics to analyze benign 67NR and malignant 4T1 breast tumor models at early and late tumor stages. Immune‐related proteins–osteopontin (Spp1), lactotransferrin (Ltf), calreticulin (Calr) and peroxiredoxin 2 (Prdx2)–were associated with systemic myeloid‐derived ...
Yeon Ji Park +6 more
wiley +1 more source
NASA/ASEE Summer Faculty Fellowship Program, 1990, Volume 1 [PDF]
The 1990 Johnson Space Center (JSC) NASA/American Society for Engineering Education (ASEE) Summer Faculty Fellowship Program was conducted by the University of Houston-University Park and JSC.
Bannerot, Richard B. +1 more
core +2 more sources
Comparison of spectroscopy technologies for improved monitoring of cell culture processes in miniature bioreactors [PDF]
, 2017 Cell culture process development requires the screening of large numbers of cell lines and process conditions. The development of miniature bioreactor systems has increased the throughput of such studies; however, there are limitations with their use ...
Abu-Absi +40 more
core +2 more sources
Using Advanced Cell Culture Techniques to Differentiate Pluripotent Stem Cells and Recreate Tissue Structures Representative of Teratoma Xenografts. [PDF]
Front Cell Dev Biol, 2021 Smith LA +5 more
europepmc +1 more source
Stochastic variation in the FOXM1 transcription program mediates replication stress tolerance
Molecular Oncology, EarlyView.Cellular heterogeneity is a major cause of drug resistance in cancer. Segeren et al. used single‐cell transcriptomics to investigate gene expression events that correlate with sensitivity to the DNA‐damaging drugs gemcitabine and prexasertib. They show that dampened expression of transcription factor FOXM1 and its target genes protected cells against ...
Hendrika A. Segeren +4 more
wiley +1 more source