Results 121 to 130 of about 15,988,140 (311)
Multiscale modelling of cancer progression and treatment control : the role of intracellular heterogeneities in chemotherapy treatment [PDF]
, 2015 Cancer is a complex, multiscale process involving interactions at intracellular, intercellular and tissue scales that are in turn susceptible to microenvironmental changes.
Chaplain, Mark Andrew Joseph +1 more
core +1 more source
Consequences of simulated microgravity in neural stem cells: biological effects and metabolic response. [PDF]
, 2015 Objective: Microgravity was often shown to cause cell damage and impair cell cycle in a variety of biological systems. Since the effects on the neural system were poorly investigated, we aimed to gain insight into how biological processes such as cell ...
ABBALLE, LUANA +15 more
core +1 more source
Nature Communications, 2018 Ubiquitination and ubiquitin-like modifications of proteins regulate multiple cellular processes but identifying substrates of specific E2 and E3 enzymes remains challenging. Here, the authors conjugate E2 enzymes with enrichable ubiquitin derivatives to
Gábor Bakos +6 more
doaj +1 more source
Cell cycle checkpoint signaling through the ATM and ATR kinases.
Genes & Development, 2001 The genomes of eukaryotic cells are under continuous assault by environmental agents (e.g., UV light and reactive chemicals) as well as the byproducts of normal intracellular metabolism (e.g., reactive oxygen intermediates and inaccurately replicated DNA)
R. Abraham
semanticscholar +1 more source
Influence of cell cycle phase on calcification in the coccolithophore Emiliania huxleyi [PDF]
, 2008 Calcification of the cosmopolitan coccolithophore species Emiliania huxleyi was investigated in relation to the cell division cycle with the use of batch cultures.
Antia, Avan +2 more
core +1 more source
DNA damage signalling histone H2AX is required for tumour growth
Cell Death DiscoveryCancer most frequently develops in self-renewal tissues that are the target of genetic alterations due to mutagens or intrinsic DNA replication errors.
Lizbeth Contreras +3 more
doaj +1 more source
Cell Reports, 2020 Summary: Cells have developed protein quality-control strategies to manage the accumulation of misfolded substrates during heat stress. Using a soluble reporter of misfolding in fission yeast, Rho1.C17R-GFP, we demonstrate that upon mild heat shock, the ...
Margarita Cabrera +6 more
doaj
The cell cycle related rhythms, cells' states correlation and the cancer [PDF]
arXiv, 2015 We consider the decision making by mammalian cells, looking them as dynamic systems with rhythms. We calculate the effective dimension of the cell division model of the healthy mammalian cells consistent with the data: it is described via a four dimensional dynamic system. We assume that the cell's decision making property is strongly affected by the
arxiv
DEPENDENCE OF CELL-TYPE PROPORTIONING AND SORTING ON CELL CYCLE PHASE IN DICTYOSTELIUM DISCOIDEUM [PDF]
, 1984 The relationship between the cell cycle phase of vegetative amoebae and prestalk and prespore differentiation in the slug stage were investigated in the slime mould Dictyostelium discoideum.
David, Charles N. +2 more
core
Cell Reports, 2013 In fission yeast, the transcription factor Pap1 undergoes H2O2-dependent oxidation that promotes its nuclear accumulation and the activation of an antioxidant gene program.
Isabel A. Calvo +5 more
doaj +1 more source