Results 71 to 80 of about 8,365,967 (315)

Comparative and functional analysis of the archaeal cell cycle

, 2010
The temporal and spatial organization of the chromosome replication, genome segregation and cell division processes is less well understood in species belonging to the Archaea, than in those from the Bacteria and eukarya domains.
Bernander, Rolf,, Lundgren, Magnus,, Thijs J. G. Ettema, Magnus Lundgren, Rolf Bernander, Ettema, Thijs J. G.,, Lundgren, Magnus, Ettema, Thijs J.G., Bernander, Rolf   +8 more
core   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Nrm1 is a bistable switch connecting cell cycle progression to transcriptional control

EMBO Reports
Entry into the cell cycle requires activation of G1 cyclin-dependent kinases (CDKs) and the G1/S transcriptional program. In fission yeast, the MBF complex is the main transcription factor driving early cell-cycle gene expression.
Guillem Murciano-Julià, Montserrat Vega, Esther Pazo, Àlex Pascual-Serra, Isabel Alves-Rodrigues, Oriol Bagudanch, Roger Anglada, Núria Bonet, Rosa Aligué, Sergio Moreno, Baldo Oliva, Elena Hidalgo, José Ayté   +12 more
doaj   +1 more source

The cell cycle and cancer [PDF]

Proceedings of the National Academy of Sciences, 1997
The process of replicating DNA and dividing a cell can be described as a series of coordinated events that compose a “cell division cycle,” illustrated for mammalian cells in Fig. 1 (see legend for details). At least two types of cell cycle control mechanisms are recognized: a cascade of protein phosphorylations that relay a cell from one stage to the ...
K, Collins, T, Jacks, N P, Pavletich
openaire   +2 more sources

The plant-cell cycle

, 1995
The first aim of this paper is to review recent progress in identifying genes in plants homologous to cell division cycle (cdc) genes of fission yeast. In the latter, cdc genes are well-characterised. Arguably, most is known about cdc2 which encodes a 34
Dennis Francis, Francis, D., Halford, N. G., Nigel G. Halford   +3 more
core   +1 more source

Signalling, cell cycle and pluripotency in embryonic stem cells [PDF]

, 2002
Pluripotent mouse embryonic stem (ES) cells can be expanded in large numbers in vitro owing to a process of symmetrical self-renewal. Self-renewal entails proliferation with a concomitant suppression of differentiation.
Burdon, Tom, Burdon, T., Smith, A., Savatier, Pierre, Smith, Austin   +4 more
core   +1 more source

Pediatric Mediastinal Gray Zone Lymphoma With Germline TET2 Heterozygous Variant

Pediatric Blood &Cancer, EarlyView.
Matthew R. Schuelke, Julia Wang, Haley Newman, Evelyn Kurpiewski, Anne Reilly, Susan R. Rheingold, Gerald Wertheim, Moe Takeda, Daniel J. Zheng, Kaitlin Devine   +9 more
wiley   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

Stage-specific MCM protein expression in Trypanosoma cruzi: insights into metacyclogenesis and G1 arrested epimastigotes

Frontiers in Cellular and Infection Microbiology
Trypanosoma cruzi is a protozoan parasite that is the etiological agent of Chagas disease, which is endemic to Latin America with reported cases in non-endemic regions such as Europe, Asia, and Oceania due to migration. During its lifecycle, T.
Bruno Alves Santarossa, Évelin Mariani, Artur da Paixão Corrêa, Fernanda C. Costa, Martin C. Taylor, John M. Kelly, Maria Carolina Elias, Simone Guedes Calderano   +7 more
doaj   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source