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TAF15 mediates ROP16-induced apoptosis and cell cycle arrest in lung cancer. [PDF]

Parasit Vectors
Li G, Tian M, Zhou Y, Ma S, Ma S, Ge Q, Zhao Z.   +6 more
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Cell cycle arrest in Batten disease lymphoblast cells

Gene, 2013
Batten disease is an inherited neurodegenerative disorder caused by a CLN3 gene mutation. Batten disease is characterized by blindness, seizures, cognitive decline, and early death. Although apoptotic cell death is one of the pathological hallmarks of Batten disease, little is known about the regulatory mechanism of apoptosis in this disease. Since the
Sunyang, Kang, June-Bum, Kim, Tae-Hwe, Heo, Sung-Jo, Kim   +3 more
openaire   +2 more sources

Cell cycle arrest by oxaliplatin on cancer cells

Fundamental & Clinical Pharmacology, 2007
AbstractOxaliplatin (L‐OHP) is the only platinum compound to show activity in colorectal cancer. We evaluated the cytotoxicity of L‐OHP on four human cancer cell lines and its influence on the cell cycle, when treated during long exposure (72 h) and different post‐incubation times (24 or 72 h).
Sara, William-Faltaos, Dany, Rouillard, Philippe, Lechat, Gérard, Bastian   +3 more
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Quantification of Cell Cycle-Arresting Proteins

2012
Cellular senescence, which can be defined as a stress response preventing the propagation of cells that have accumulated potentially oncogenic alterations, is invariably associated with a permanent cell cycle arrest. Such an irreversible blockage is mainly mediated by the persistent upregulation of one or more cyclin-dependent kinase inhibitors (CKIs),
Oliver, Kepp, Isabelle, Martins, Laurie, Menger, Mickaël, Michaud, Sandy, Adjemian, Abdul Qader, Sukkurwala, Lorenzo, Galluzzi, Guido, Kroemer   +7 more
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Meiotic cell cycle arrest in mammalian oocytes

Journal of Cellular Physiology, 2010
AbstractMeiotic cell cycle in mammalian oocytes is a dynamic process that involves several stop/go channels. The cell cycle arrest in oocyte occurs at various stages such as diplotene, metaphase‐I (M‐I), metaphase‐II (M‐II), and so called metaphase‐like arrest (M‐III).
Anima, Tripathi, K V Prem, Kumar, Shail K, Chaube   +2 more
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Mechanisms of interferon-induced cell cycle arrest

Frontiers in Bioscience, 2000
The interferons (IFNs) are a group of cytokines, which in addition to their antiviral activity are capable of modulating a variety of cellular responses. One such prominent effect of IFNs is their potent antimitogenic action, which can be observed both on malignant and non-malignant cells of many different origins.
O, Sangfelt, S, Erickson, D, Grander
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Reversal of p53-induced cell-cycle arrest

Molecular Carcinogenesis, 1999
Activation of the tumor suppressor protein p53 can lead to arrest in both G1 and G2 stages of the cell cycle and, in some cells, to apoptotic cell death. In this study, we showed that the p53 response to a chemotherapeutic drug, actinomycin D, was reversible in both normal and tumor cells, even when a substantial proportion of tumor cells were ...
S, Bates, E S, Hickman, K H, Vousden
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Cyclin D2 ArrestsXenopusEarly Embryonic Cell Cycles

Experimental Cell Research, 1997
Xenopus cyclin D2 mRNA is a member of the class of maternal RNAs. It is rare and stable during early embryonic development. To investigate the potential role of cyclin D2 during early embryonic cell cycles, cyclin D2 was injected into one blastomere of a two-cell embryo. This injection induced a cell cycle arrest in the injected blastomere.
Taieb, Frederic, Chartrain, I., Chevalier, S., Haccard, O., Jessus, Catherine   +4 more
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Cell-cycle arrest versus cell death in cancer therapy

Nature Medicine, 1997
In response to anticancer therapeutics, human colon cancer cells growing in vitro either enter into a stable arrest or die, depending on the integrity of their cell-cycle checkpoints. To test whether altered checkpoints can modulate sensitivity to treatment in vivo, xenografts were established from isogenic lines differing only in their p21 checkpoint ...
T, Waldman, Y, Zhang, L, Dillehay, J, Yu, K, Kinzler, B, Vogelstein, J, Williams   +6 more
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Geldanamycin Induces Cell Cycle Arrest in K562 Erythroleukemic Cells

IUBMB Life, 1999
AbstractGeldanamycin (GA), a benzoquinone ansamycin, is one of the specific inhibitors of 90‐kDa heat shock protein and induces growth inhibition and apoptosis in certain cancer cell lines. We have investigated the mechanism of GA‐induced growth inhibition in K562 erythroleukemic cells.
H R, Kim, C H, Lee, Y H, Choi, H S, Kang, H D, Kim   +4 more
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