Results 21 to 30 of about 10,588,993 (295)
The centrosomal protein C-Nap1 is required for cell cycle-regulated centrosome cohesion [PDF]
, 2000 Duplicating centrosomes are paired during interphase, but are separated at the onset of mitosis. Although the mechanisms controlling centrosome cohesion and separation are important for centrosome function throughout the cell cycle, they remain poorly ...
Fry, A. M. +14 more
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p25/Cdk5-mediated retinoblastoma phosphorylation is an early event in neuronal cell death [PDF]
, 2005 In large models of neuronal cell death, there is a tight correlation between Cdk5 deregulation and cell-cycle dysfunction. However, pathways that link Cdk5 to the cell cycle during neuronal death are still unclear.
Sambo, Anne-Véronique +15 more
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Cell Division, 2012 The retinoblastoma (RB) family of proteins are found in organisms as distantly related as humans, plants, and insects. These proteins play a key role in regulating advancement of the cell division cycle from the G1 to S-phases.
Henley Shauna A, Dick Frederick A
doaj +1 more source
Regulation of Sp1 by cell cycle related proteins [PDF]
, 2021 Sp1 transcription factor regulates the expression of multiple genes, including the Sp1 gene itself. We analyzed the ability of different cell cycle regulatory proteins to interact with Sp1 and to affect Sp1 promoter activity.
Ciudad i Gómez, Carlos Julián +3 more
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Polycomb proteins and breast cancer [PDF]
, 2013 In the Western world, breast cancer is the most frequent malignancy in women and still the leading cause of cancer related deaths, therefore, a better understanding of the disease is needed.
Fedele, Vita
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Drug targets for cell cycle dysregulators in leukemogenesis: in silico docking studies. [PDF]
PLoS ONE, 2014 Alterations in cell cycle regulating proteins are a key characteristic in neoplastic proliferation of lymphoblast cells in patients with Acute Lymphoblastic Leukemia (ALL).
Archana Jayaraman, Kaiser Jamil
doaj +1 more source
Frontiers in Cell and Developmental Biology, 2019 Cell cycle regulation is essential for the development of multicellular organisms, but many cells in adulthood, including neurons, exit from cell cycle. Although cell cycle-related proteins are suppressed after cell cycle exit in general, recent studies ...
Takeshi Kawauchi +2 more
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Late phase cell cycle proteins in Alzheimer’s disease: a possible target for therapy? [PDF]
, 2016 Alzheimer’s disease (AD) is represented by neuronal loss and this loss is correlated to a constant state of neuronal instability induced by intrinsic and extrinsic factors.
Bajic, Vladan +5 more
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PIN1 in Cell Cycle Control and Cancer
Frontiers in Pharmacology, 2018 Cell cycle progression is tightly controlled by many cell cycle-regulatory proteins that are in turn regulated by a family of cyclin-dependent kinases (CDKs) through protein phosphorylation. The peptidyl-prolyl cis/trans isomerase PIN1 provides a further
Chi-Wai Cheng, Eric Tse
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Mathematics, 2022 Biological processes are governed by the expression of proteins, and for some proteins, their level of expression can fluctuate periodically over time (i.e., they oscillate).
Andrew Rowntree +2 more
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