Alternative Functions of Cell Cycle-Related and DNA Repair Proteins in Post-mitotic Neurons
Frontiers in Cell and Developmental Biology, 2021 Proper regulation of neuronal morphological changes is essential for neuronal migration, maturation, synapse formation, and high-order function. Many cytoplasmic proteins involved in the regulation of neuronal microtubules and the actin cytoskeleton have
Remi Akagawa +3 more
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Cell cycle-regulated protein abundance changes in synchronously proliferating HeLa cells include regulation of pre-mRNA splicing proteins. [PDF]
PLoS ONE, 2013 Cell proliferation involves dramatic changes in DNA metabolism and cell division, and control of DNA replication, mitosis, and cytokinesis have received the greatest attention in the cell cycle field.
Karen R Lane +5 more
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S100A8 calcium-binding expression in radicular and dentigerous cysts and in keratocystic odontogenic tumors [PDF]
Stomatološki glasnik Srbije, 2008 Introduction: Recently the term Keratocystic Odontogenic Tumor (KCOT) has been recommended for Odontogenic Keratocysts (OKC) to address the neoplastic nature of the lesion compared to radicular and dentigerous cysts.
Iezzi Giovanna +7 more
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Cell Cycle Control by Optogenetically Regulated Cell Cycle Inhibitor Protein p21
Biology, 2023 The progression through the cell cycle phases is driven by cyclin-dependent kinases and cyclins as their regulatory subunits. As nuclear protein, the cell cycle inhibitor p21/CDKN1A arrests the cell cycle at the growth phase G1 by inhibiting the activity of cyclin-dependent kinases.
Levin Lataster +5 more
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Targeting Cell-cycle Machinery in Cancer
Cancer Cell, 2021 SUMMARY Abnormal activity of the core cell-cycle machinery is seen in essentially all tumor types and represents a driving force of tumorigenesis. Recent studies revealed that cell-cycle proteins regulate a wide range of cellular functions, in addition ...
Jan M Suski +3 more
semanticscholar +1 more source
Switching the Cell Cycle. Kip-Related Proteins in Plant Cell Cycle Control [PDF]
Plant Physiology, 2005 During the development of multicellular organisms, many different cell types are created. These display characteristic cell cycle programs that can radically change during the organism's lifetime ([Jakoby and Schnittger, 2004][1]; [Fig. 1][2]).
Verkest, Aurine +4 more
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Dynamic proteomics of human protein level and localization across the cell cycle. [PDF]
PLoS ONE, 2012 Regulation of proteins across the cell cycle is a basic process in cell biology. It has been difficult to study this globally in human cells due to lack of methods to accurately follow protein levels and localizations over time. Estimates based on global
Shlomit Farkash-Amar +8 more
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Cell cycle on the crossroad of tumorigenesis and cancer therapy
Trends in Cell Biology, 2021 Aberrancy in cell cycle progression is one of the fundamental mechanisms underlying tumorigenesis, making regulators of the cell cycle machinery rational anti-cancer therapeutic targets.
Jing Liu, Yunhua Peng, Wenyi Wei
semanticscholar +1 more source
Fluorescent Reporters and Biosensors for Probing the Dynamic Behavior of Protein Kinases
Proteomes, 2015 Probing the dynamic activities of protein kinases in real-time in living cells constitutes a major challenge that requires specific and sensitive tools tailored to meet the particular demands associated with cellular imaging.
Juan A. González-Vera, May C. Morris
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Cells, 2022 Psoriasis is a persistent T-cell-supported inflammatory cutaneous disorder, which is defined by a significant expansion of basal cells in the epidermis. Cell cycle and STAT genes that control cell cycle progression and viral infection have been revealed ...
Subhashini Dorai, Daniel Alex Anand
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