Results 31 to 40 of about 8,709,387 (250)

Fate specification and tissue-specific cell cycle control of the Caenorhabditis elegans intestine [PDF]

open access: yes, 2010
Coordination between cell fate specification and cell cycle control in multicellular organisms is essential to regulate cell numbers in tissues and organs during development, and its failure may lead to oncogenesis.
Segref, Alexandra   +9 more
core   +1 more source

Nuclear translocation of Cyclin B1 marks the restriction point for terminal cell cycle exit in G2 phase [PDF]

open access: yes, 2014
Upon DNA damage, cell cycle progression is temporally blocked to avoid propagation of mutations. While transformed cells largely maintain the competence to recover from a cell cycle arrest, untransformed cells past the G1/S transition lose mitotic ...
Jaiswal, H.   +9 more
core   +1 more source

Drug targets for cell cycle dysregulators in leukemogenesis: in silico docking studies. [PDF]

open access: yesPLoS ONE, 2014
Alterations in cell cycle regulating proteins are a key characteristic in neoplastic proliferation of lymphoblast cells in patients with Acute Lymphoblastic Leukemia (ALL).
Archana Jayaraman, Kaiser Jamil
doaj   +1 more source

Growth Arrest Triggers Extra-Cell Cycle Regulatory Function in Neurons: Possible Involvement of p27kip1 in Membrane Trafficking as Well as Cytoskeletal Regulation

open access: yesFrontiers in Cell and Developmental Biology, 2019
Cell cycle regulation is essential for the development of multicellular organisms, but many cells in adulthood, including neurons, exit from cell cycle. Although cell cycle-related proteins are suppressed after cell cycle exit in general, recent studies ...
Takeshi Kawauchi   +2 more
doaj   +1 more source

Analysis of cyclic di-GMP signaling components in "caulobacter crescentus" behavior and cell cycle control [PDF]

open access: yes, 2013
Cell cycle progression and polar morphogenesis in Caulobacter crescentus are coordinated by the interplay of multiple proteins in time and space. One major regulatory factor is the second messenger cyclic di-GMP (c-di-GMP) therefore especially the ...
Friedrich, Elvira
core   +1 more source

PIN1 in Cell Cycle Control and Cancer

open access: yesFrontiers in Pharmacology, 2018
Cell cycle progression is tightly controlled by many cell cycle-regulatory proteins that are in turn regulated by a family of cyclin-dependent kinases (CDKs) through protein phosphorylation. The peptidyl-prolyl cis/trans isomerase PIN1 provides a further
Chi-Wai Cheng, Eric Tse
doaj   +1 more source

Rapid regulation of protein activity in fission yeast [PDF]

open access: yes, 2014
Background: The fission yeast Schizosaccharomyces pombe is widely-used as a model organism for the study of a broad range of eukaryotic cellular processes such as cell cycle, genome stability and cell morphology. Despite the availability of extensive set
Sharom, Jeffrey R.   +9 more
core   +1 more source

A map of protein dynamics during cell-cycle progression and cell-cycle exit.

open access: yesPLoS Biology, 2017
The cell-cycle field has identified the core regulators that drive the cell cycle, but we do not have a clear map of the dynamics of these regulators during cell-cycle progression versus cell-cycle exit.
Sara Gookin   +7 more
doaj   +1 more source

Bilateral Feedback in Oscillator Model Is Required to Explain the Coupling Dynamics of Hes1 with the Cell Cycle

open access: yesMathematics, 2022
Biological processes are governed by the expression of proteins, and for some proteins, their level of expression can fluctuate periodically over time (i.e., they oscillate).
Andrew Rowntree   +2 more
doaj   +1 more source

Dynamical Analysis of Yeast Cell Cycle Using a Stochastic Markov Model

open access: yesمجله انفورماتیک سلامت و زیست پزشکی, 2021
Introduction: The cell cycle network is responsible of control, growth and proliferation of cells. The relationship between the cell cycle network and cancer emergence, and the complex reciprocal interactions between genes/proteins calls for ...
Sajad Shafiekhani   +4 more
doaj  

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