Results 31 to 40 of about 4,494,876 (293)

Expression of regulatory proteins and proliferative activity in relation to phenotypic characteristics of upper urothelial carcinoma [PDF]

open access: yesVojnosanitetski Pregled, 2011
Background/Aim. Deregulation of the normal cell cycle is common in upper urothelial carcinoma (UUC). The aim of this study was to investigate the expression of regulatory proteins of the cell cycle (p53, p16, cyclin D1, HER-2) and proliferative Ki-67 ...
Dolićanin Zana   +6 more
doaj   +1 more source

The Influence of Cell Cycle Regulation on Chemotherapy

open access: yesInternational Journal of Molecular Sciences, 2021
Cell cycle regulation is orchestrated by a complex network of interactions between proteins, enzymes, cytokines, and cell cycle signaling pathways, and is vital for cell proliferation, growth, and repair.
Ying Sun, Yang Liu, Xiaoli Ma, Hao Hu
semanticscholar   +1 more source

Mitotic cell cycle proteins increase in podocytes despite lack of proliferation

open access: yesKidney International, 2003
Jeffrey Kopp   +2 more
exaly   +2 more sources

The retinoblastoma family of proteins and their regulatory functions in the mammalian cell division cycle

open access: yesCell Division, 2012
The retinoblastoma (RB) family of proteins are found in organisms as distantly related as humans, plants, and insects. These proteins play a key role in regulating advancement of the cell division cycle from the G1 to S-phases.
Henley Shauna A, Dick Frederick A
doaj   +1 more source

Ubiquitination-mediated degradation of cell cycle-related proteins by F-box proteins

open access: yesInternational Journal of Biochemistry and Cell Biology, 2016
F-box proteins, subunits of SKP1-cullin 1-F-box protein (SCF) type of E3 ubiquitin ligase complexes, have been validated to play a crucial role in governing various cellular processes such as cell cycle, cell proliferation, apoptosis, migration, invasion
Nana Zheng, Zhiwei Wang, Wenyi Wei
semanticscholar   +1 more source

Drug targets for cell cycle dysregulators in leukemogenesis: in silico docking studies. [PDF]

open access: yesPLoS ONE, 2014
Alterations in cell cycle regulating proteins are a key characteristic in neoplastic proliferation of lymphoblast cells in patients with Acute Lymphoblastic Leukemia (ALL).
Archana Jayaraman, Kaiser Jamil
doaj   +1 more source

Growth Arrest Triggers Extra-Cell Cycle Regulatory Function in Neurons: Possible Involvement of p27kip1 in Membrane Trafficking as Well as Cytoskeletal Regulation

open access: yesFrontiers in Cell and Developmental Biology, 2019
Cell cycle regulation is essential for the development of multicellular organisms, but many cells in adulthood, including neurons, exit from cell cycle. Although cell cycle-related proteins are suppressed after cell cycle exit in general, recent studies ...
Takeshi Kawauchi   +2 more
doaj   +1 more source

PIN1 in Cell Cycle Control and Cancer

open access: yesFrontiers in Pharmacology, 2018
Cell cycle progression is tightly controlled by many cell cycle-regulatory proteins that are in turn regulated by a family of cyclin-dependent kinases (CDKs) through protein phosphorylation. The peptidyl-prolyl cis/trans isomerase PIN1 provides a further
Chi-Wai Cheng, Eric Tse
doaj   +1 more source

Bilateral Feedback in Oscillator Model Is Required to Explain the Coupling Dynamics of Hes1 with the Cell Cycle

open access: yesMathematics, 2022
Biological processes are governed by the expression of proteins, and for some proteins, their level of expression can fluctuate periodically over time (i.e., they oscillate).
Andrew Rowntree   +2 more
doaj   +1 more source

Delayed expression of cell cycle proteins contributes to astroglial scar formation and chronic inflammation after rat spinal cord contusion

open access: yesJournal of Neuroinflammation, 2012
Traumatic spinal cord injury (SCI) induces secondary tissue damage that is associated with astrogliosis and inflammation. We previously reported that acute upregulation of a cluster of cell-cycle-related genes contributes to post-mitotic cell death and ...
Junfang Wu   +5 more
semanticscholar   +1 more source

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