Results 31 to 40 of about 10,588,993 (295)
Dynamical Analysis of Yeast Cell Cycle Using a Stochastic Markov Model
Introduction: The cell cycle network is responsible of control, growth and proliferation of cells. The relationship between the cell cycle network and cancer emergence, and the complex reciprocal interactions between genes/proteins calls for ...
Sajad Shafiekhani +4 more
doaj
FUNDAMENTOS: O carcinoma basocelular é o câncer mais comum em humanos. Estudos que utilizam recursos da biologia molecular e genética, associados à histomorfologia, permitem a identificação de fatores de risco no desenvolvimento de lesões mais ...
Marília de Pádua Dornelas Corrêa +4 more
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Chromosome segregation is a crucial stage of the cell cycle. In general, proteins involved in this process are DNA-binding proteins, and in most bacteria, ParA and ParB are the main players; however, some bacteria manage this process by employing other ...
Monika Pióro, Dagmara Jakimowicz
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Proteins Made in the Mammalian Cell Cycle
DNA-binding proteins made by Chinese hamster ovary (CHO) cells at specific times in their cell cycle were chromatographed on DNA-cellulose and analyzed with sodium dodecyl sulfate polyacrylamide electrophoresis. Some small proteins (less than 25,000 mol wt) were made in S (the period of DNA synthesis), but not during G1 (the period following mitosis ...
T O, Fox, A B, Pardee
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Cell cycle gene expression programs fuel proliferation and are universally dysregulated in cancer. The retinoblastoma (RB)-family of proteins, RB1, RBL1/p107, and RBL2/p130, coordinately represses cell cycle gene expression, inhibiting proliferation, and
Taylor P Enrico +8 more
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Endothelin-1 Activates MAPKs and Modulates Cell Cycle Proteins in OKP Cells
The signaling mechanisms through which endothelin (ET)-1 induces hyperplasia of the renal tubular epithelium are largely unknown. Methods: These mechanisms were explored using ETB-overexpressing opossum kidney (OKP) cells as a model system. Results: ET-1
Tzong-Shinn Chu +3 more
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Pocket proteins and cell cycle control [PDF]
The retinoblastoma protein (pRB) and the pRB-related p107 and p130 comprise the 'pocket protein' family of cell cycle regulators. These proteins are best known for their roles in restraining the G1-S transition through the regulation of E2F-responsive genes.
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C-Nap1, a novel centrosomal coiled-coil protein and candidate substrate of the cell cycle-regulated protein kinase Nek2 [PDF]
Nek2 (for NIMA-related kinase 2) is a mammalian cell cycle-regulated kinase structurally related to the mitotic regulator NIMA of Aspergillus nidulans.
Fry, A. M. +23 more
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The crosstalk between non-coding RNAs and cell-cycle events: A new frontier in cancer therapy
The cell cycle comprises sequential events during which a cell duplicates its genome and divides it into two daughter cells. This process is tightly regulated to ensure that the daughter cell receives identical copied chromosomal DNA and that any errors ...
Anup S. Pathania +5 more
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Anticancer activity of Opuntia cochenillifera extract against triple-negative breast cancer cells via apoptosis induction and bioinformatics-based target prediction [PDF]
Background/Aim: Breast cancer remains one of the most commonly diagnosed cancers among women worldwide and is a significant public health concern. Aim of this study was to investigate the in vitro anticancer activity of Opuntia cochenillifera ethanolic ...
Alaydrus Ali Akbar +2 more
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