Results 31 to 40 of about 4,494,876 (293)
Expression of regulatory proteins and proliferative activity in relation to phenotypic characteristics of upper urothelial carcinoma [PDF]
Background/Aim. Deregulation of the normal cell cycle is common in upper urothelial carcinoma (UUC). The aim of this study was to investigate the expression of regulatory proteins of the cell cycle (p53, p16, cyclin D1, HER-2) and proliferative Ki-67 ...
Dolićanin Zana +6 more
doaj +1 more source
The Influence of Cell Cycle Regulation on Chemotherapy
Cell cycle regulation is orchestrated by a complex network of interactions between proteins, enzymes, cytokines, and cell cycle signaling pathways, and is vital for cell proliferation, growth, and repair.
Ying Sun, Yang Liu, Xiaoli Ma, Hao Hu
semanticscholar +1 more source
Mitotic cell cycle proteins increase in podocytes despite lack of proliferation
Jeffrey Kopp +2 more
exaly +2 more sources
The retinoblastoma (RB) family of proteins are found in organisms as distantly related as humans, plants, and insects. These proteins play a key role in regulating advancement of the cell division cycle from the G1 to S-phases.
Henley Shauna A, Dick Frederick A
doaj +1 more source
Ubiquitination-mediated degradation of cell cycle-related proteins by F-box proteins
F-box proteins, subunits of SKP1-cullin 1-F-box protein (SCF) type of E3 ubiquitin ligase complexes, have been validated to play a crucial role in governing various cellular processes such as cell cycle, cell proliferation, apoptosis, migration, invasion
Nana Zheng, Zhiwei Wang, Wenyi Wei
semanticscholar +1 more source
Drug targets for cell cycle dysregulators in leukemogenesis: in silico docking studies. [PDF]
Alterations in cell cycle regulating proteins are a key characteristic in neoplastic proliferation of lymphoblast cells in patients with Acute Lymphoblastic Leukemia (ALL).
Archana Jayaraman, Kaiser Jamil
doaj +1 more source
Cell cycle regulation is essential for the development of multicellular organisms, but many cells in adulthood, including neurons, exit from cell cycle. Although cell cycle-related proteins are suppressed after cell cycle exit in general, recent studies ...
Takeshi Kawauchi +2 more
doaj +1 more source
PIN1 in Cell Cycle Control and Cancer
Cell cycle progression is tightly controlled by many cell cycle-regulatory proteins that are in turn regulated by a family of cyclin-dependent kinases (CDKs) through protein phosphorylation. The peptidyl-prolyl cis/trans isomerase PIN1 provides a further
Chi-Wai Cheng, Eric Tse
doaj +1 more source
Biological processes are governed by the expression of proteins, and for some proteins, their level of expression can fluctuate periodically over time (i.e., they oscillate).
Andrew Rowntree +2 more
doaj +1 more source
Traumatic spinal cord injury (SCI) induces secondary tissue damage that is associated with astrogliosis and inflammation. We previously reported that acute upregulation of a cluster of cell-cycle-related genes contributes to post-mitotic cell death and ...
Junfang Wu +5 more
semanticscholar +1 more source

