Results 51 to 60 of about 1,866,493 (305)
The crosstalk between non-coding RNAs and cell-cycle events: A new frontier in cancer therapy
Molecular Therapy: OncologyThe cell cycle comprises sequential events during which a cell duplicates its genome and divides it into two daughter cells. This process is tightly regulated to ensure that the daughter cell receives identical copied chromosomal DNA and that any errors ...
Anup S. Pathania +5 more
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Dynamical Analysis of Yeast Cell Cycle Using a Stochastic Markov Model
مجله انفورماتیک سلامت و زیست پزشکی, 2021 Introduction: The cell cycle network is responsible of control, growth and proliferation of cells. The relationship between the cell cycle network and cancer emergence, and the complex reciprocal interactions between genes/proteins calls for ...
Sajad Shafiekhani +4 more
doaj
eLife, 2017 Ubiquilins (Ubqlns) are a family of ubiquitin receptors that promote the delivery of hydrophobic and aggregated ubiquitinated proteins to the proteasome for degradation.
Alexandra M Whiteley +16 more
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Modelling how plant cell-cycle progression leads to cell size regulation.
PLoS Computational Biology, 2023 Populations of cells typically maintain a consistent size, despite cell division rarely being precisely symmetrical. Therefore, cells must possess a mechanism of "size control", whereby the cell volume at birth affects cell-cycle progression.
Daniel Williamson +4 more
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Quantification of DNA-associated proteins inside eukaryotic cells using single-molecule localization microscopy [PDF]
, 2014 Development of single-molecule localization microscopy techniques has allowed nanometre scale localization accuracy inside cells, permitting the resolution of ultra-fine cell structure and the elucidation of crucial molecular mechanisms.
Adam T. Watson +46 more
core +1 more source
Protein transduction: A novel tool for tissue regeneration [PDF]
, 2002 Tissue regeneration in humans is limited and excludes vitals organs like heart and brain. Transformation experiments with oncogenes like T antigen have shown that retrodifferentiation of the respective cells is possible but hard to control. To bypass the
Derer W. +4 more
core +1 more source
Cell cycle-dependent variations in protein concentration [PDF]
Nucleic Acids Research, 2009 Computational modeling of biological systems has become an effective tool for analyzing cellular behavior and for elucidating key properties of the intricate networks that underlie experimental observations. While most modeling techniques rely heavily on the concentrations of intracellular molecules, little attention has been paid to tracking and ...
Cookson, Natalie A. +3 more
openaire +2 more sources
Intravitreal GD2‐Specific Chimeric Antigen Receptor T‐Cell Therapy for Refractory Retinoblastoma
Pediatric Blood &Cancer, EarlyView.ABSTRACT Effective treatments for advanced, treatment‐resistant retinoblastoma (RB) remain limited. GD2‐specific chimeric antigen receptor (CAR) T cells show potent antitumor activity with minimal toxicity but have not previously been evaluated in RB.
Subongkoch Subhadhirasakul +13 more
wiley +1 more source
Frontiers in Neuroscience, 2018 Adult neurogenesis (AN) is an ongoing developmental process that generates newborn neurons in the olfactory bulb (OB) and the hippocampus (Hi) throughout life and significantly contributes to brain plasticity.
Saad Omais, Carine Jaafar, Noël Ghanem
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Oscillatory dynamics of cell cycle proteins in single yeast cells analyzed by imaging cytometry. [PDF]
PLoS ONE, 2011 Progression through the cell division cycle is orchestrated by a complex network of interacting genes and proteins. Some of these proteins are known to fluctuate periodically during the cell cycle, but a systematic study of the fluctuations of a broad ...
David A Ball +6 more
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