Results 41 to 50 of about 8,709,387 (250)
Frontiers in Microbiology, 2020 Chromosome segregation is a crucial stage of the cell cycle. In general, proteins involved in this process are DNA-binding proteins, and in most bacteria, ParA and ParB are the main players; however, some bacteria manage this process by employing other ...
Monika Pióro, Dagmara Jakimowicz
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Late phase cell cycle proteins in Alzheimer’s disease: a possible target for therapy? [PDF]
, 2016 Alzheimer’s disease (AD) is represented by neuronal loss and this loss is correlated to a constant state of neuronal instability induced by intrinsic and extrinsic factors.
Bajic, Vladan +5 more
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eLife, 2021 Cell cycle gene expression programs fuel proliferation and are universally dysregulated in cancer. The retinoblastoma (RB)-family of proteins, RB1, RBL1/p107, and RBL2/p130, coordinately represses cell cycle gene expression, inhibiting proliferation, and
Taylor P Enrico +8 more
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Frontiers in Neuroscience, 2018 Adult neurogenesis (AN) is an ongoing developmental process that generates newborn neurons in the olfactory bulb (OB) and the hippocampus (Hi) throughout life and significantly contributes to brain plasticity.
Saad Omais, Carine Jaafar, Noël Ghanem
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Polycomb proteins and breast cancer [PDF]
, 2013 In the Western world, breast cancer is the most frequent malignancy in women and still the leading cause of cancer related deaths, therefore, a better understanding of the disease is needed.
Fedele, Vita
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Anais Brasileiros de Dermatologia, 2009 FUNDAMENTOS: O carcinoma basocelular é o câncer mais comum em humanos. Estudos que utilizam recursos da biologia molecular e genética, associados à histomorfologia, permitem a identificação de fatores de risco no desenvolvimento de lesões mais ...
Marília de Pádua Dornelas Corrêa +4 more
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Modelling how plant cell-cycle progression leads to cell size regulation.
PLoS Computational Biology, 2023 Populations of cells typically maintain a consistent size, despite cell division rarely being precisely symmetrical. Therefore, cells must possess a mechanism of "size control", whereby the cell volume at birth affects cell-cycle progression.
Daniel Williamson +4 more
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The crosstalk between non-coding RNAs and cell-cycle events: A new frontier in cancer therapy
Molecular Therapy: OncologyThe cell cycle comprises sequential events during which a cell duplicates its genome and divides it into two daughter cells. This process is tightly regulated to ensure that the daughter cell receives identical copied chromosomal DNA and that any errors ...
Anup S. Pathania +5 more
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Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Endothelin-1 Activates MAPKs and Modulates Cell Cycle Proteins in OKP Cells
Journal of the Formosan Medical Association, 2007 The signaling mechanisms through which endothelin (ET)-1 induces hyperplasia of the renal tubular epithelium are largely unknown. Methods: These mechanisms were explored using ETB-overexpressing opossum kidney (OKP) cells as a model system. Results: ET-1
Tzong-Shinn Chu +3 more
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