Results 41 to 50 of about 4,494,876 (293)

Dynamical Analysis of Yeast Cell Cycle Using a Stochastic Markov Model

open access: yesمجله انفورماتیک سلامت و زیست پزشکی, 2021
Introduction: The cell cycle network is responsible of control, growth and proliferation of cells. The relationship between the cell cycle network and cancer emergence, and the complex reciprocal interactions between genes/proteins calls for ...
Sajad Shafiekhani   +4 more
doaj  

Ubiquilin1 promotes antigen-receptor mediated proliferation by eliminating mislocalized mitochondrial proteins

open access: yeseLife, 2017
Ubiquilins (Ubqlns) are a family of ubiquitin receptors that promote the delivery of hydrophobic and aggregated ubiquitinated proteins to the proteasome for degradation.
Alexandra M Whiteley   +16 more
doaj   +1 more source

Proteins Made in the Mammalian Cell Cycle

open access: yesJournal of Biological Chemistry, 1971
DNA-binding proteins made by Chinese hamster ovary (CHO) cells at specific times in their cell cycle were chromatographed on DNA-cellulose and analyzed with sodium dodecyl sulfate polyacrylamide electrophoresis. Some small proteins (less than 25,000 mol wt) were made in S (the period of DNA synthesis), but not during G1 (the period following mitosis ...
T O, Fox, A B, Pardee
openaire   +2 more sources

Chromosome Segregation Proteins as Coordinators of Cell Cycle in Response to Environmental Conditions

open access: yesFrontiers in Microbiology, 2020
Chromosome segregation is a crucial stage of the cell cycle. In general, proteins involved in this process are DNA-binding proteins, and in most bacteria, ParA and ParB are the main players; however, some bacteria manage this process by employing other ...
Monika Pióro, Dagmara Jakimowicz
doaj   +1 more source

Cyclin F drives proliferation through SCF-dependent degradation of the retinoblastoma-like tumor suppressor p130/RBL2

open access: yeseLife, 2021
Cell cycle gene expression programs fuel proliferation and are universally dysregulated in cancer. The retinoblastoma (RB)-family of proteins, RB1, RBL1/p107, and RBL2/p130, coordinately represses cell cycle gene expression, inhibiting proliferation, and
Taylor P Enrico   +8 more
doaj   +1 more source

Pocket proteins and cell cycle control [PDF]

open access: yesOncogene, 2005
The retinoblastoma protein (pRB) and the pRB-related p107 and p130 comprise the 'pocket protein' family of cell cycle regulators. These proteins are best known for their roles in restraining the G1-S transition through the regulation of E2F-responsive genes.
openaire   +2 more sources

The crosstalk between non-coding RNAs and cell-cycle events: A new frontier in cancer therapy

open access: yesMolecular Therapy: Oncology
The cell cycle comprises sequential events during which a cell duplicates its genome and divides it into two daughter cells. This process is tightly regulated to ensure that the daughter cell receives identical copied chromosomal DNA and that any errors ...
Anup S. Pathania   +5 more
doaj   +1 more source

“Till Death Do Us Part”: A Potential Irreversible Link Between Aberrant Cell Cycle Control and Neurodegeneration in the Adult Olfactory Bulb

open access: yesFrontiers in Neuroscience, 2018
Adult neurogenesis (AN) is an ongoing developmental process that generates newborn neurons in the olfactory bulb (OB) and the hippocampus (Hi) throughout life and significantly contributes to brain plasticity.
Saad Omais, Carine Jaafar, Noël Ghanem
doaj   +1 more source

Ectopic Cell Cycle Proteins Predict the Sites of Neuronal Cell Death in Alzheimer’s Disease Brain

open access: yesJournal of Neuroscience, 1998
Alzheimer’s disease (AD) is a major dementing illness characterized by regional concentrations of senile plaques, neurofibrillary tangles, and extensive neuronal cell death.
J. Busser, D. Geldmacher, K. Herrup
semanticscholar   +1 more source

Expressão de marcadores de proliferação celular e apoptose em carcinoma basocelular Markers expression of cell proliferation and apoptosis in basal cell carcinoma

open access: yesAnais Brasileiros de Dermatologia, 2009
FUNDAMENTOS: O carcinoma basocelular é o câncer mais comum em humanos. Estudos que utilizam recursos da biologia molecular e genética, associados à histomorfologia, permitem a identificação de fatores de risco no desenvolvimento de lesões mais ...
Marília de Pádua Dornelas Corrêa   +4 more
doaj   +1 more source

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