Results 71 to 80 of about 3,883,823 (304)
E3 Ubiquitin Ligase TRIM Proteins, Cell Cycle and Mitosis
Cells, 2019 The cell cycle is a series of events by which cellular components are accurately segregated into daughter cells, principally controlled by the oscillating activities of cyclin-dependent kinases (CDKs) and their co-activators.
Santina Venuto, Giuseppe Merla
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Protein Folding across the Cell Cycle [PDF]
Biophysical Journal, 2013 The mammalian cell cycle is the biological pathway through which cells grow and divide. During this physically dramatic process the cell doubles in size, duplicates its genetic material, dissolves its nucleus, and ultimately divides into two genetically identical daughter cells.
Wirth, Anna J., Gruebele, Martin
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The role and implications of mammalian cellular circadian entrainment
FEBS Letters, EarlyView.At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
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Effect of resveratrol on cell cycle proteins in murine transplantable liver cancer.
World Journal of Gastroenterology, 2003 AIM To study the antitumour activity of resveratrol and its effect on the expression of cell cycle proteins including cyclin D1, cyclin B1 and p34cdc2 in transplanted liver cancer of murine.
Liang Yu +3 more
semanticscholar +1 more source
Molecular bases of circadian magnesium rhythms across eukaryotes
FEBS Letters, EarlyView.Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
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Proteins Made in the Mammalian Cell Cycle
Journal of Biological Chemistry, 1971 DNA-binding proteins made by Chinese hamster ovary (CHO) cells at specific times in their cell cycle were chromatographed on DNA-cellulose and analyzed with sodium dodecyl sulfate polyacrylamide electrophoresis. Some small proteins (less than 25,000 mol wt) were made in S (the period of DNA synthesis), but not during G1 (the period following mitosis ...
T O, Fox, A B, Pardee
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Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
FEBS Letters, EarlyView.Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
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Cell Cycle Proteins Exhibit Altered Expression Patterns in Lentiviral-Associated Encephalitis
Journal of Neuroscience, 2002 Cell cycle proteins regulate processes as diverse as cell division and cell death. Recently their role in neuronal death has been reported in several models of neurodegeneration.
K. Jordan-Sciutto +3 more
semanticscholar +1 more source
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
FEBS Letters, EarlyView.The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
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PLoS Pathogens, 2019 The cell division cycle of the unicellular eukaryote Trypanosome brucei is tightly regulated despite the paucity of transcriptional control that results from the arrangement of genes in polycistronic units and lack of dynamically regulated transcription ...
Corinna Benz, Michael D Urbaniak
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