Results 71 to 80 of about 1,825,024 (378)
BPTF promotes tumor growth and predicts poor prognosis in lung adenocarcinomas. [PDF]
, 2015 BPTF, a subunit of NURF, is well known to be involved in the development of eukaryotic cell, but little is known about its roles in cancers, especially in non-small-cell lung cancer (NSCLC).
Dai, Meng +14 more
core +3 more sources
Journal of Oncological SciencesObjective: Mesenchymal stem cell (MSC)-based IL-12 release therapy may be less toxic than direct administration of IL-2. We investigated the release of interleukin (IL)-12 in MSCs and A549 cocultures and identified the time points at which IL-12 is ...
Meliha Burcu IRMAK YAZICIOĞLU +1 more
doaj +1 more source
eLife, 2017 Ubiquilins (Ubqlns) are a family of ubiquitin receptors that promote the delivery of hydrophobic and aggregated ubiquitinated proteins to the proteasome for degradation.
Alexandra M Whiteley +16 more
doaj +1 more source
Effects of DCA on Cell Cycle Proteins in Colonocytes [PDF]
Journal of the Korean Society of Coloproctology, 2010 Evidence that indicates bile acid is a promoter of colon cancer exists. Deoxycholic acid (DCA) modifies apoptosis or proliferation by affecting intracellular signaling and gene expression. However, because previous studies have been based on studies on colon cancer cell lines, the effect of DCA on normal colonocytes is unknown.Normal colonocytes and ...
Yun-Hyung Ha, Dong-Guk Park
openaire +3 more sources
Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia
FEBS Letters, EarlyView.This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley +1 more source
Physiological and transcriptomic evidence for a close coupling between chloroplast ontogeny and cell cycle progression in the pennate diatom Seminavis robusta [PDF]
, 2008 Despite the growing interest in diatom genomics, detailed time series of gene expression in relation to key cellular processes are still lacking. Here, we investigated the relationships between the cell cycle and chloroplast development in the pennate ...
Chepurnov, Victor A +12 more
core +3 more sources
Cell cycle-dependent variations in protein concentration [PDF]
Nucleic Acids Research, 2009 Computational modeling of biological systems has become an effective tool for analyzing cellular behavior and for elucidating key properties of the intricate networks that underlie experimental observations. While most modeling techniques rely heavily on the concentrations of intracellular molecules, little attention has been paid to tracking and ...
Jeff Hasty +3 more
openaire +3 more sources
The Yeast Cell-Cycle Network Is Robustly Designed [PDF]
PNAS 101, 4781 (2004)., 2003 The interactions between proteins, DNA, and RNA in living cells constitute molecular networks that govern various cellular functions. To investigate the global dynamical properties and stabilities of such networks, we studied the cell-cycle regulatory network of the budding yeast.
arxiv +1 more source
Functional variation among LPMOs revealed by the inhibitory effects of cyanide and buffer ions
FEBS Letters, EarlyView.This study addresses the inhibition of lytic polysaccharide monooxygenases (LPMOs) by cyanide and explains how and why the magnitude of observed inhibitory effects depends on the way LPMO reactions are setup and on the type of LPMO. Enzymes known as lytic polysaccharide monooxygenases (LPMOs) are mono‐copper polysaccharide‐degrading peroxygenases that ...
Ole Golten +10 more
wiley +1 more source
Root-knot nematode feeding site development is impaired by cyclin-dependent kinase inhibitors [PDF]
, 2012 Plant-parasitic nematodes of the genera Meloidogyne trigger the formation of giant cells that undergo recurring acytokinetic mitosis and endocycles. Expression analyses of key cell cycle genes showed their early induction in the nematode feeding site ...
Abad, Pierre +5 more
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