Results 151 to 160 of about 12,907,435 (362)

Dose‐dependent induction of epithelial‐mesenchymal transition in 3D melanoma models by non‐thermal plasma treatment

Molecular Oncology, EarlyView.
Non‐thermal plasma treatment of melanoma cells induced epithelial‐mesenchymal transition (EMT) in a dose‐dependent fashion. This report highlights the critical need to further investigate potential adverse effects of non‐thermal plasma for cancer therapy and to optimize treatment parameters for clinical translation. Despite the promising results of non‐
Eline Biscop, Edgar Cardenas De La Hoz, Hanne Verswyvel, Joey De Backer, Ho Wa Lau, Angela Privat‐Maldonado, Wim Vanden Berghe, Steve Vanlanduit, Evelien Smits, Annemie Bogaerts, Abraham Lin   +10 more
wiley   +1 more source

Addendum: TGF-β signaling alters H4K20me3 status via miR-29 and contributes to cellular senescence and cardiac aging

Nature Communications, 2018
Guoliang Lyu, Yiting Guan, Chao Zhang, Le Zong, Lei Sun, Xiaoke Huang, Li Huang, Lijun Zhang, Xiao-Li Tian, Zhongjun Zhou, Wei Tao   +10 more
doaj   +1 more source

Electron Microscopic Studies of the Differentiation of Fat Cells in Human Fetal Skin**From the Department of Dermatology, Yamaguchi University, School of Medicine, Ube, Japan.

, 1969
Hidesuke Fujita, Chidori Asagami, Yoshihiko Oda, Takashi Mori, Yoshiko Suetomi   +4 more
openalex   +1 more source

Regulatory T Cells in Skin Facilitate Epithelial Stem Cell Differentiation

Cell, 2017
N. Ali, Bahar Zirak, Robert Sanchez Rodriguez, M. Pauli, H. Truong, K. Lai, R. Ahn, Kaitlin Corbin, Margaret M. Lowe, T. Scharschmidt, Keyon Taravati, Madeleine R. Tan, R. Ricardo-Gonzalez, A. Nosbaum, M. Bertolini, W. Liao, F. Nestle, R. Paus, G. Cotsarelis, A. Abbas, M. Rosenblum   +20 more
semanticscholar   +1 more source

Molecular imaging predicts trastuzumab‐deruxtecan (T‐DXd) response in head and neck cancer xenograft models

Molecular Oncology, EarlyView.
Trastuzumab‐deruxtecan, a HER2‐targeting antibody‐drug conjugate, shows promising antitumor activity in head and neck squamous cell carcinoma with low HER2 expression. In vitro and in vivo studies demonstrated dose‐dependent cell death and tumor growth reduction in low HER2‐expressing cell lines, which correlated with drug accumulation measured using a
Abdullah Bin Naveed, Lucas Mani, Muhammad Bilal Mirza, Ashtyn McAdoo, Takahito Kondo, Hidenori Tanaka, Nicole Meeks, Eben Rosenthal, Marisa Hom   +8 more
wiley   +1 more source

Radioautographic Evidence of DNA Synthesis in Well-differentiated Cells of Human Skin Papillomas (Verrucae Vulgares)**From the Department of Microbiology, School of Medicine, University of Washington, Seattle, Washington 98105.

, 1969
Abdel L. Rashad
openalex   +1 more source

Epithelial–mesenchymal transition (EMT): A biological process in the development, stem cell differentiation, and tumorigenesis

Journal of Cellular Physiology, 2017
Tong Chen, Y. You, Hua Jiang, Zack Z Wang   +3 more
semanticscholar   +1 more source

Genomics‐led approach to drug testing in models of undifferentiated pleomorphic sarcoma

Molecular Oncology, EarlyView.
GA text Genomic data from undifferentiated pleomorphic sarcoma patients and preclinical models were used to inform a targeted drug screen. Selected compounds were tested in 2D and 3D cultures of UPS cell lines. A combination of trametinib and infigratinib was synergistic in the majority of UPS cell lines tested, which was further confirmed in an ex ...
Piotr J. Manasterski, Molly R. Danks, John P. Thomson, Morwenna Muir, Martin Lee, John C. Dawson, Ana T. Amaral, Juan Diaz‐Martin, David S. Moura, Javier Martin‐Broto, Ali Alsaadi, Donald M. Salter, Ailsa J. Oswald, Graeme Grimes, Larry Hayward, Ted R. Hupp, Karen Sisley, Paul H. Huang, Neil O. Carragher, Valerie G. Brunton   +19 more
wiley   +1 more source

Mitotic ER-mitochondria contact enhances mitochondrial Ca2+ influx to promote cell division

Cell Reports
Summary: Cell division is tightly regulated and requires an expanded energy supply. However, how this energy is generated remains unclear. Here, we establish a correlation between two mitochondrial Ca2+ influx events and ATP production during mitosis ...
Gan Zhao, Mingkang Jia, Shicong Zhu, He Ren, Guopeng Wang, Guangwei Xin, Mengjie Sun, Xiangyang Wang, Qiaoyu Lin, Qing Jiang, Chuanmao Zhang   +10 more
doaj  

Oxygen Consumption of Basal and Differentiating Cells from Hairless Mouse Epidermis

, 1969
Ole Didrik
openalex   +1 more source