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Erythroid cell differentiation
Molecular and Cellular Biochemistry, 1978Normal and transformed erythroid cell precursors provide the opportunity for study of a number of problems relevant to the regulation of proliferation and differentiation in a developmental system. Evidence is presented which suggests that the hormone, erythropoietin, has a primary role in regulating precursor cell proliferation.
Richard A. Rifkind+2 more
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Synchronous Cell Differentiation
1968Publisher Summary Synchronous cell differentiation refers to the occurrence of simultaneous cellular transformations throughout a population of cells. Although the induction of cell division synchrony may be a prerequisite for such an experimental situation, it need not be the primary concern of the investigator.
Ivan L. Cameron+3 more
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Differentiation of Human T Cells
Clinics in Laboratory Medicine, 1988This article discusses the ontogeny of human T cells along with the relationship of normal T-cell maturation to the development of various malignant T-cell syndromes. The impact of monoclonal antibody technology, the discovery of the T-cell receptor for antigen, and the discovery of mechanisms of thymocyte-thymic microenvironment interactions on the ...
Barton F. Haynes, Stephen M. Denning
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Differentiation and Characterization of T Cells
Current Protocols in Immunology, 2005AbstractThis paper outlines current standard methods of inducing T lymphopoiesis in vitro and in vivo. Reference is made to both murine and human systems. In addition to differentiation assays, methods to optimally characterize output cells are discussed.
Paul Robertson, David T. Scadden
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Erythroid Cell Differentiation
1976We have reviewed erythroid cell differentiation from two points of view: 1) differences between fetal and adult human red cells with particular reference to alterations which can occur in the normal pattern of erythroid cell development during the course of leukemia; 2) beochemical events which occur during erythroid cell maturation, as a model system ...
Jonatham Glass+2 more
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Current Opinion in Cell Biology, 1989
The appeal of myogenic differentiation as a model developmental system derives in part from the complexity of regulatory steps required to account for the diversity of muscle structure and function. The intricate patterns of contractile tissue formation in the adult animal depend on the orderly progression of molecular signals that lead primordial ...
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The appeal of myogenic differentiation as a model developmental system derives in part from the complexity of regulatory steps required to account for the diversity of muscle structure and function. The intricate patterns of contractile tissue formation in the adult animal depend on the orderly progression of molecular signals that lead primordial ...
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Current Opinion in Immunology, 1999
The differentiation of Th cells is regulated at different points by antigen and by other factors in a complex fashion that allows impressive flexibility in the T cell response generated and enables close control at multiple points to prevent an unwanted response.
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The differentiation of Th cells is regulated at different points by antigen and by other factors in a complex fashion that allows impressive flexibility in the T cell response generated and enables close control at multiple points to prevent an unwanted response.
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Ageing in Differentiated Cells
Gerontology, 1974The effect of ageing on growth, function and cell loss in differentiated cells is reviewed briefly. Although there is some evidence of loss of function and of delay in the initiation of cell division in ageing cells, there is no evidence of massive cell loss. It is unlikely that an overall loss of cells or cell malfunction is responsible for limitation
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