Helper T cell differentiation [PDF]
Cellular & Molecular Immunology, 2019 CD4+ T helper cells are key regulators of host health and disease. In the original model, specialized subsets of T helper cells are generated following activation through lineage-specifying cytokines and transcriptional programs, but recent studies have revealed increasing complexities for CD4+ T-cell differentiation. Here, we first discuss CD4+ T-cell
Jordy Saravia +2 more
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The properties of nerve cell precursors in hydra [PDF]
, 1986 Two signals, the head activator and an injury stimulus, control differentiation of nerve cells from uncommitted stem cells in hydra [Th. Holstein, H. C. Schaller, and C. N. David, (1986) Dev. Biol. 115, 9–17].
David, Charles N., Holstein, Thomas W.
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The C/EBPβ LIP isoform rescues loss of C/EBPβ function in the mouse
Scientific Reports, 2018 The transcription factor C/EBPβ regulates hematopoiesis, bone, liver, fat, and skin homeostasis, and female reproduction. C/EBPβ protein expression from its single transcript occurs by alternative in-frame translation initiation at consecutive start ...
Valérie Bégay +4 more
doaj +1 more source
YAP integrates the regulatory Snail/HNF4α circuitry controlling epithelial/hepatocyte differentiation [PDF]
, 2019 Yes-associated protein (YAP) is a transcriptional co-factor involved in many cell processes, including development, proliferation, stemness, differentiation, and tumorigenesis.
Amicone, Laura +8 more
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LSD1-mediated enhancer silencing attenuates retinoic acid signalling during pancreatic endocrine cell development. [PDF]
, 2020 Developmental progression depends on temporally defined changes in gene expression mediated by transient exposure of lineage intermediates to signals in the progenitor niche.
Benner, Christopher W +14 more
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Involvement of ST6Gal I‐mediated α2,6 sialylation in myoblast proliferation and differentiation
FEBS Open Bio, 2020 Myogenesis is a physiological process which involves the proliferation of myoblasts and their differentiation into multinucleated myotubes, which constitute the future muscle fibers.
Caroline Vergé +5 more
doaj +1 more source
, 1998 Basic problems for the construction of a scenario for the Life are discussed. To study the problems in terms of dynamical systems theory, a scheme of intra-inter dynamics is presented.
Kaneko K. +7 more
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Cannabidiol stimulates AML-1a-dependent glial differentiation and inhibits glioma stem-like cells proliferation by inducing autophagy in a TRPV2-dependent manner [PDF]
, 2015 Glioma stem-like cells (GSCs) correspond to a tumor cell subpopulation, involved in glioblastoma multiforme (GBM) tumor ini- tiation and acquired chemoresistance.
Amantini, Consuelo +7 more
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Prostaglandin E2 promotes intestinal repair through an adaptive cellular response of the epithelium [PDF]
, 2017 Adaptive cellular responses are often required during wound repair. Following disruption of the intestinal epithelium, wound‐associated epithelial (WAE) cells form the initial barrier over the wound.
Lai, Chin-Wen +7 more
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Geometric control of myogenic cell fate. [PDF]
, 2006 This work combines expertise in stem cell biology and bioengineering to define the system for geometric control of proliferation and differentiation of myogenic progenitor cells.
Conboy IM +9 more
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