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Principles of dormancy evident in high-grade serous ovarian cancer
Cell Division, 2022 In cancer, dormancy refers to a clinical state in which microscopic residual disease becomes non-proliferative and is largely refractory to chemotherapy.
Trevor G. Shepherd, Frederick A. Dick
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WormBook, 2006 The C. elegans embryo is a powerful model system for studying the mechanics of metazoan cell division. Its primary advantage is that the architecture of the syncytial gonad makes it possible to use RNAi to generate oocytes whose cytoplasm is reproducibly (typically >95%) depleted of targeted essential gene products via a process that does not depend ...
Karen, Oegema, Anthony A, Hyman
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Chemical Society Reviews, 2023 In this review, we summarize the strategies of inducing division in synthetic cells by using physical, chemical, and biological stimuli, and highlight the future challenges to the construction of autonomous synthetic cell division.
Mu-Yueh Chang +3 more
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Cell Division, 2023 Background Nucleosome-localized sirtuin 4 (SIRT4) was found to function as an oncogene and tumor suppressor gene in different tumors. However, the clinical significance of SIRT4 in bladder urothelial carcinoma (BLCA) has not been assessed, nor has the ...
Jie Yin +5 more
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Cell Division: The Prehistorichore? [PDF]
Current Biology, 2014 The recent discovery of a novel kinetochore has important implications for our understanding of the evolution of chromosome segregation systems and also for the treatment of devastating parasitic diseases.
Thomas J. Maresca, Stuart Cane
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Cell division in Corynebacterineae [PDF]
Frontiers in Microbiology, 2014 Bacterial cells must coordinate a number of events during the cell cycle. Spatio-temporal regulation of bacterial cytokinesis is indispensable for the production of viable, genetically identical offspring. In many rod-shaped bacteria, precise midcell assembly of the division machinery relies on inhibitory systems such as Min and Noc.
Donovan, Catriona, Bramkamp, Marc
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Cell Division, 2018 Just like all matter, proteins can also switch between gas, liquid and solid phases. Protein phase transition has claimed the spotlight in recent years as a novel way of how cells compartmentalize and regulate biochemical reactions.
Steven Boeynaems +2 more
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ESCRT-III mediated cell division in Sulfolobus acidocaldarius - a reconstitution perspective [PDF]
, 2014 In the framework of synthetic biology, it has become an intriguing question what would be the minimal representation of cell division machinery. Thus, it seems appropriate to compare how cell division is realized in different microorganisms. Inparticular,
Härtel, T., Schwille, P.
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Protein arginine methylation: an emerging regulator of the cell cycle
Cell Division, 2018 Protein arginine methylation is a common post-translational modification where a methyl group is added onto arginine residues of a protein to alter detection by its binding partners or regulate its activity.
Anita E. Raposo, Sabine C. Piller
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PDE models of adder mechanisms in cellular proliferation [PDF]
, 2020 Cell division is a process that involves many biochemical steps and complex biophysical mechanisms. To simplify the understanding of what triggers cell division, three basic models that subsume more microscopic cellular processes associated with cell ...
Chou, Tom +2 more
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