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The mechanism of cell division [PDF]
The recently developed approximation method for treating problems of cell biophysics is generalized and corrected in some points. The equations of elongation of a dividing cell of any shape are given for the most general case of finite permeability as well as of finite internal and external diffusion coefficients.
N. Rashevsky
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Principles of dormancy evident in high-grade serous ovarian cancer
In cancer, dormancy refers to a clinical state in which microscopic residual disease becomes non-proliferative and is largely refractory to chemotherapy.
Trevor G. Shepherd, Frederick A. Dick
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The C. elegans embryo is a powerful model system for studying the mechanics of metazoan cell division. Its primary advantage is that the architecture of the syncytial gonad makes it possible to use RNAi to generate oocytes whose cytoplasm is reproducibly (typically >95%) depleted of targeted essential gene products via a process that does not depend ...
Karen, Oegema, Anthony A, Hyman
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In this review, we summarize the strategies of inducing division in synthetic cells by using physical, chemical, and biological stimuli, and highlight the future challenges to the construction of autonomous synthetic cell division.
Mu-Yueh Chang+3 more
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Cell Division: The Prehistorichore? [PDF]
The recent discovery of a novel kinetochore has important implications for our understanding of the evolution of chromosome segregation systems and also for the treatment of devastating parasitic diseases.
Thomas J. Maresca, Stuart Cane
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Cell division in Corynebacterineae [PDF]
Bacterial cells must coordinate a number of events during the cell cycle. Spatio-temporal regulation of bacterial cytokinesis is indispensable for the production of viable, genetically identical offspring. In many rod-shaped bacteria, precise midcell assembly of the division machinery relies on inhibitory systems such as Min and Noc.
Donovan, Catriona, Bramkamp, Marc
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Differences in cell death and division rules can alter tissue rigidity and fluidization [PDF]
Tissue mechanical properties such as rigidity and fluidity, and changes in these properties driven by jamming-unjamming transitions (UJT), have come under recent highlight as mechanical markers of health and disease in various biological processes including cancer.
arxiv +1 more source
Emerging roles of the SUMO pathway in mitosis
SUMO proteins are small ubiquitin-like modifiers found in all eukaryotes that become covalently conjugated to other cellular proteins. The SUMO conjugation pathway is biochemically similar to ubiquitin conjugation, although the enzymes within the pathway
Dasso Mary
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Kinesin-5 Eg5 is essential for spindle assembly and chromosome alignment of mouse spermatocytes
Background Microtubule organization is essential for bipolar spindle assembly and chromosome segregation, which contribute to genome stability. Kinesin-5 Eg5 is known to be a crucial regulator in centrosome separation and spindle assembly in mammalian ...
Zhen-Yu She+7 more
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