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A mechanistic first--passage time framework for bacterial cell-division timing [PDF]
How exponentially growing cells maintain size homeostasis is an important fundamental problem. Recent single-cell studies in prokaryotes have uncovered the adder principle, where cells on average, add a fixed size (volume) from birth to division ...
Ghusinga, Khem Raj+2 more
core +4 more sources
Cell division: a source of active stress in cellular monolayers [PDF]
We introduce the notion of cell division-induced activity and show that the cell division generates extensile forces and drives dynamical patterns in cell assemblies.
Doostmohammadi, Amin+5 more
core +2 more sources
Metabolic maintenance of cell asymmetry following division in activated T lymphocytes
Asymmetric cell division, the partitioning of cellular components in response to polarizing cues during mitosis, has roles in differentiation and development.
Katherine C Verbist+2 more
exaly +2 more sources
Branching Feller diffusion for cell division with parasite infection [PDF]
We describe the evolution of the quantity of parasites in a population of cells which divide in continuous-time. The quantity of parasites in a cell follows a Feller diffusion, which is splitted randomly between the two daughter cells when a division ...
Bansaye, Vincent, Tran, Viet Chi
core +2 more sources
Principles of dormancy evident in high-grade serous ovarian cancer
In cancer, dormancy refers to a clinical state in which microscopic residual disease becomes non-proliferative and is largely refractory to chemotherapy.
Trevor G. Shepherd, Frederick A. Dick
doaj +1 more source
Commentary: locating the restriction point
Attempts to map the Restriction Point in the mammalian cell cycle typically involve stimulating quiescent cells with mitogens for increasing intervals, removing the stimulus and then determining the proportion of cells that reach S phase at some point ...
Robert F. Brooks
doaj +1 more source
MPS1 is involved in the HPV16-E7-mediated centrosomes amplification
Background It has been reported that the oncoprotein E7 from human papillomavirus type 16 (HPV16-E7) can induce the excessive synthesis of centrosomes through the increase in the expression of PLK4, which is a transcriptional target of E2F1. On the other
Yair Alfaro-Mora+7 more
doaj +1 more source
Genetic requirements for cell division in a genomically minimal cell
Genomically minimal cells, such as JCVI-syn3.0, offer a platform to clarify genes underlying core physiological processes. While this minimal cell includes genes essential for population growth, the physiology of its single cells remained uncharacterized.
J. Pelletier+11 more
semanticscholar +1 more source
Cell growth dilutes the cell cycle inhibitor Rb to trigger cell division
A cell size sensor Efforts continue to uncover the long-sought mechanism by which cells coordinate growth and cell division to maintain a constant size. Zatulovskiy et al.
E. Zatulovskiy+4 more
semanticscholar +1 more source