Results 11 to 20 of about 1,295,502 (307)
Can eukaryotic cells monitor the presence of unreplicated DNA?
Cell Division, 2007 Completion of DNA replication before mitosis is essential for genome stability and cell viability. Cellular controls called checkpoints act as surveillance mechanisms capable of detecting errors and blocking cell cycle progression to allow time for those
Aragón Luis +2 more
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The role of CDK in the initiation step of DNA replication in eukaryotes
Cell Division, 2007 Cyclin-dependent kinases (CDKs) regulate the progression of the cell cycle in eukaryotes. One of the major roles of CDK is to promote chromosomal DNA replication.
Tak Yon-Soo +2 more
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Reconstruction of the kinetochore: a prelude to meiosis
Cell Division, 2007 In eukaryotic organisms, chromosomes are spatially organized within the nucleus. Such nuclear architecture provides a physical framework for the genetic activities of chromosomes, and changes its functional organization as the cell moves through the ...
Haraguchi Tokuko +2 more
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How eggs arrest at metaphase II: MPF stabilisation plus APC/C inhibition equals Cytostatic Factor
Cell Division, 2007 Oocytes from higher chordates, including man and nearly all mammals, arrest at metaphase of the second meiotic division before fertilization. This arrest is due to an activity that has been termed 'Cytostatic Factor'.
Jones Keith T, Madgwick Suzanne
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Merotelic attachments and non-homologous end joining are the basis of chromosomal instability
Cell Division, 2010 Although the large majority of solid tumors show a combination of mitotic spindle defects and chromosomal instability, little is known about the mechanisms that govern the initial steps in tumorigenesis.
van Wely Karel HM +2 more
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p27kip1 at the crossroad between actin and microtubule dynamics
Cell Division, 2019 The p27kip1 protein, mainly known as a negative regulator of cell proliferation, has also been involved in the control of other cellular processes, including the regulation of cytoskeleton dynamics.
Gian Luca Rampioni Vinciguerra +5 more
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Cell Division, 2019 The anaphase-promoting complex/cyclosome (APC/C) is a multi-subunit, multifunctional ubiquitin ligase that controls the temporal degradation of numerous cell cycle regulatory proteins to direct the unidirectional cell cycle phases.
Shivangee Bansal, Swati Tiwari
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JAB1/CSN5: a new player in cell cycle control and cancer
Cell Division, 2010 c-Jun activation domain-binding protein-1 (Jab1) acts as a modulator of intracellular signaling and affects cellular proliferation and apoptosis, through its existence as a monomer or as the fifth component of the constitutive photomorphogenic-9 ...
Claret Francois X, Shackleford Terry J
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Expression of genes regulating cell division in porcine follicular granulosa cells
Cell Division, 2023 Background Cell cycle regulation influences the proliferation of granulosa cells and affects many processes related to ovarian folliclular growth and ovulation. Abnormal regulation of the cell cycle can lead to many diseases within the ovary.
Jakub Kulus +7 more
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Resolving RAD51C function in late stages of homologous recombination
Cell Division, 2007 DNA double strand breaks are efficiently repaired by homologous recombination. One of the last steps of this process is resolution of Holliday junctions that are formed at the sites of genetic exchange between homologous DNA.
Kuznetsov Sergey G, Sharan Shyam K
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