Reconstruction of the kinetochore: a prelude to meiosis
Cell Division, 2007 In eukaryotic organisms, chromosomes are spatially organized within the nucleus. Such nuclear architecture provides a physical framework for the genetic activities of chromosomes, and changes its functional organization as the cell moves through the ...
Haraguchi Tokuko +2 more
doaj +1 more source
How eggs arrest at metaphase II: MPF stabilisation plus APC/C inhibition equals Cytostatic Factor
Cell Division, 2007 Oocytes from higher chordates, including man and nearly all mammals, arrest at metaphase of the second meiotic division before fertilization. This arrest is due to an activity that has been termed 'Cytostatic Factor'.
Jones Keith T, Madgwick Suzanne
doaj +1 more source
Merotelic attachments and non-homologous end joining are the basis of chromosomal instability
Cell Division, 2010 Although the large majority of solid tumors show a combination of mitotic spindle defects and chromosomal instability, little is known about the mechanisms that govern the initial steps in tumorigenesis.
van Wely Karel HM +2 more
doaj +1 more source
p27kip1 at the crossroad between actin and microtubule dynamics
Cell Division, 2019 The p27kip1 protein, mainly known as a negative regulator of cell proliferation, has also been involved in the control of other cellular processes, including the regulation of cytoskeleton dynamics.
Gian Luca Rampioni Vinciguerra +5 more
doaj +1 more source
Cell Division, 2019 The anaphase-promoting complex/cyclosome (APC/C) is a multi-subunit, multifunctional ubiquitin ligase that controls the temporal degradation of numerous cell cycle regulatory proteins to direct the unidirectional cell cycle phases.
Shivangee Bansal, Swati Tiwari
doaj +1 more source
JAB1/CSN5: a new player in cell cycle control and cancer
Cell Division, 2010 c-Jun activation domain-binding protein-1 (Jab1) acts as a modulator of intracellular signaling and affects cellular proliferation and apoptosis, through its existence as a monomer or as the fifth component of the constitutive photomorphogenic-9 ...
Claret Francois X, Shackleford Terry J
doaj +1 more source
Expression of genes regulating cell division in porcine follicular granulosa cells
Cell Division, 2023 Background Cell cycle regulation influences the proliferation of granulosa cells and affects many processes related to ovarian folliclular growth and ovulation. Abnormal regulation of the cell cycle can lead to many diseases within the ovary.
Jakub Kulus +7 more
doaj +1 more source
A mechanistic first--passage time framework for bacterial cell-division timing
, 2015 How exponentially growing cells maintain size homeostasis is an important fundamental problem. Recent single-cell studies in prokaryotes have uncovered the adder principle, where cells on average, add a fixed size (volume) from birth to division ...
Ghusinga, Khem Raj +2 more
core +1 more source
Deficiency of RgpG causes major defects in cell division and biofilm formation, and deficiency of LytR-CpsAPsr family proteins leads to accumulation of cell wall antigens in culture medium by Streptococcus mutans [PDF]
, 2017 Streptococcus mutans is known to possess rhamnose-glucose polysaccharide (RGP), a major cell wall antigen. S. mutans strains deficient in rgpG , encoding the first enzyme of the RGP biosynthesis
Beatty, Wandy L +6 more
core +2 more sources
Resolving RAD51C function in late stages of homologous recombination
Cell Division, 2007 DNA double strand breaks are efficiently repaired by homologous recombination. One of the last steps of this process is resolution of Holliday junctions that are formed at the sites of genetic exchange between homologous DNA.
Kuznetsov Sergey G, Sharan Shyam K
doaj +1 more source