Results 31 to 40 of about 2,334,308 (350)
Mitofusin 1 is degraded at G2/M phase through ubiquitylation by MARCH5
Background Mitochondria exhibit a dynamic morphology in cells and their biogenesis and function are integrated with the nuclear cell cycle. In mitotic cells, the filamentous network structure of mitochondria takes on a fragmented form.
Park Yong-Yea, Cho Hyeseong
doaj +1 more source
Forward Genetic Dissection of Biofilm Development by Fusobacterium nucleatum: Novel Functions of Cell Division Proteins FtsX and EnvC. [PDF]
Fusobacterium nucleatum is a key member of the human oral biofilm. It is also implicated in preterm birth and colorectal cancer. To facilitate basic studies of fusobacterial virulence, we describe here a versatile transposon mutagenesis procedure and a ...
Abu Amar Mohamed Al Mamun+10 more
core +2 more sources
MPS1 is involved in the HPV16-E7-mediated centrosomes amplification
Background It has been reported that the oncoprotein E7 from human papillomavirus type 16 (HPV16-E7) can induce the excessive synthesis of centrosomes through the increase in the expression of PLK4, which is a transcriptional target of E2F1. On the other
Yair Alfaro-Mora+7 more
doaj +1 more source
There are four general ideas about animals that would seldom be challenged: 1) the protoplasm of animals is organized into cells; 2) nearly all cells are so small as to be invisible to the human eye; 3) animals are generally clearly visible because they consist of many cells; but 4) most animals arise from single cells (zygotes).
G. S. Garoian, R. E. Blackwelder
openaire +2 more sources
How eggs arrest at metaphase II: MPF stabilisation plus APC/C inhibition equals Cytostatic Factor
Oocytes from higher chordates, including man and nearly all mammals, arrest at metaphase of the second meiotic division before fertilization. This arrest is due to an activity that has been termed 'Cytostatic Factor'.
Jones Keith T, Madgwick Suzanne
doaj +1 more source
Commentary: locating the restriction point
Attempts to map the Restriction Point in the mammalian cell cycle typically involve stimulating quiescent cells with mitogens for increasing intervals, removing the stimulus and then determining the proportion of cells that reach S phase at some point ...
Robert F. Brooks
doaj +1 more source
A mechanistic first--passage time framework for bacterial cell-division timing
How exponentially growing cells maintain size homeostasis is an important fundamental problem. Recent single-cell studies in prokaryotes have uncovered the adder principle, where cells on average, add a fixed size (volume) from birth to division ...
Ghusinga, Khem Raj+2 more
core +1 more source
SYNCHRONIZATION OF CELL DIVISION [PDF]
A culture of unicellular organisms growing at because events in different clones are not in phase maximal rate under constant conditions contains with each other. cells at all stages of the division cycle. The relaWhen conditions are not constant, as when the tive frequencies of cells of different ages-i.e., the stationary phase is approached, growth ...
openaire +3 more sources
Merotelic attachments and non-homologous end joining are the basis of chromosomal instability
Although the large majority of solid tumors show a combination of mitotic spindle defects and chromosomal instability, little is known about the mechanisms that govern the initial steps in tumorigenesis.
van Wely Karel HM+2 more
doaj +1 more source
Emerging roles of the SUMO pathway in mitosis
SUMO proteins are small ubiquitin-like modifiers found in all eukaryotes that become covalently conjugated to other cellular proteins. The SUMO conjugation pathway is biochemically similar to ubiquitin conjugation, although the enzymes within the pathway
Dasso Mary
doaj +1 more source