Results 31 to 40 of about 2,429,942 (292)

Rapid and accurate genotyping of human SNP rs671 in aldehyde dehydrogenase 2 gene using one-step CRISPR/Cas12b assay without DNA amplification

Cell Division, 2023
Background The SNP rs671 of Human aldehyde dehydrogenase (ALDH) is G-A transition at 1510th nucleotides, which is an important clinical indicator of alcoholic liver disease, digestive tract cancer and some drug efficiency.
Fang Wu, Yong Xue, Yan Wang, Xinxin Si, Xinyue Zhang, Yuyang Xu, Zhidan Luo   +6 more
doaj   +1 more source

Dynamic changes in ANGUSTIFOLIA3 complex composition reveal a growth regulatory mechanism in the maize leaf [PDF]

, 2015
Most molecular processes during plant development occur with a particular spatio-temporal specificity. Thus far, it has remained technically challenging to capture dynamic protein-protein interactions within a growing organ, where the interplay between ...
Aesaert, Stijn, Candaele, Jasper, De Block, Jolien, De Jaeger, Geert, Demuynck, Kirin, Eeckhout, Dominique, Gevaert, Kris, Goormachtig, Sofie, Inzé, Dirk, Muszynski, Michael, Nelissen, Hilde, Persiau, Geert, Van Bel, Michiel, Van Leene, Jelle, Van Lijsebettens, Maria, Vandepoele, Klaas, Vervoort, Marieke, Walton, Alan   +17 more
core   +2 more sources

CLK3 promotes tumor proliferation by activating MYC signaling

Cell Division
Colorectal cancer (CRC) ranks among the leading causes of cancer-related mortality worldwide, posing a significant public health challenge. Despite advancements in treatment strategies, prognosis for advanced CRC remains poor.
Jing Shen, Yu Zhao, Yang Man, Xuling Sun
doaj   +1 more source

Promiscuous and lineage-specific roles of cell cycle regulators in haematopoiesis

Cell Division, 2007
Haematopoietic cell number is maintained by a delicate balance between cell proliferation, differentiation and death. Gene knockout studies in mice have revealed the complex roles of cyclins, CDKs, and CDK inhibitors in regulating cell proliferation and ...
Lam Eric, Myatt Stephen S
doaj   +1 more source

MPS1 is involved in the HPV16-E7-mediated centrosomes amplification

Cell Division, 2021
Background It has been reported that the oncoprotein E7 from human papillomavirus type 16 (HPV16-E7) can induce the excessive synthesis of centrosomes through the increase in the expression of PLK4, which is a transcriptional target of E2F1. On the other
Yair Alfaro-Mora, Guadalupe Domínguez-Gómez, Rodrigo E. Cáceres-Gutiérrez, Laura Tolentino-García, Luis A. Herrera, Clementina Castro-Hernández, Rosa María Bermúdez-Cruz, José Díaz-Chávez   +7 more
doaj   +1 more source

Modelling protein localisation and positional information in subcellular systems [PDF]

, 2008
Cells and their component structures are highly organised. The correct function of many biological systems relies upon not only temporal control of protein levels but also spatial control of protein localisation within cells.
Tostevin, Filipe John, Tostevin, Filipe John   +1 more
core   +1 more source

A Quality Improvement Initiative to Standardize Pneumocystis jirovecii Pneumonia Prophylaxis in Pediatric Patients With Solid Tumors

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Pediatric patients with extracranial solid tumors (ST) receiving chemotherapy are at an increased risk for Pneumocystis jirovecii pneumonia (PJP). However, evidence guiding prophylaxis practices in this population is limited. A PJP‐related fatality at our institution highlighted inconsistent prescribing approaches and concerns about
Kriti Kumar, Denise M. Connolly, Ellen Kellington, Elyse Zelunka, Karla Kerrigan, Furqan Shaikh, Paul C. Nathan, Meredith S. Irwin, Sarah Cohen‐Gogo   +8 more
wiley   +1 more source

LncPRESS1 promotes the progression and cisplatin resistance of breast cancer through upregulation of ENO1 and activation of glycolysis

Cell Division
Background Overexpression or downregulation of long noncoding RNA (lncRNA) plays an essential role in the progression and chemotherapy-resistant of breast cancer (BRCA). LncPRESS1 is a lncRNA regulated by p53, suggesting its potential in participating in
Longzhu Ke, Wei Gao, Yuanxiu Leng, Jie Chen, Hong Chen, Shangshang Li, Yingwen Zhang, Li Luo   +7 more
doaj   +1 more source

Measuring DNA content in live cells by fluorescence microscopy

Cell Division, 2018
Background Live-cell fluorescence microscopy (LCFM) is a powerful tool used to investigate cellular dynamics in real time. However, the capacity to simultaneously measure DNA content in cells being tracked over time remains challenged by dye-associated ...
Cecil J. Gomes, Michael W. Harman, Sara M. Centuori, Charles W. Wolgemuth, Jesse D. Martinez   +4 more
doaj   +1 more source

Staphylococcus aureus DivIB is a peptidoglycan-binding protein that is required for a morphological checkpoint in cell division [PDF]

, 2014
Bacterial cell division is a fundamental process that requires the coordinated actions of a number of proteins which form a complex macromolecular machine known as the divisome.
Bottomley, Amy L., Foster, Simon J., Garcia-Lara, Jorge, Hurd, Alexander F., Kabli, Azhar F., Turner, Robert D.   +5 more
core   +1 more source