Results 31 to 40 of about 1,174,140 (120)
Restriction beyond the restriction point: mitogen requirement for G2 passage
Cell Division, 2006 Cell proliferation is dependent on mitogenic signalling. When absent, normal cells cannot pass the G1 restriction point, resulting in cell cycle arrest.
te Riele Hein, Foijer Floris
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Emerging players in the initiation of eukaryotic DNA replication
Cell Division, 2012 Faithful duplication of the genome in eukaryotes requires ordered assembly of a multi-protein complex called the pre-replicative complex (pre-RC) prior to S phase; transition to the pre-initiation complex (pre-IC) at the beginning of DNA replication ...
Shen Zhen, Prasanth Supriya G
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The WW-HECT protein Smurf2 interacts with the Docking Protein NEDD9/HEF1 for Aurora A activation
Cell Division, 2010 The multi-functional adaptor protein NEDD9/HEF1/Cas-L regulates cell motility, invasion and cell cycle progression, and plays key roles in cancer progression and metastasis.
Moore Finola E +6 more
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Preventing DNA over-replication: a Cdk perspective
Cell Division, 2008 The cell cycle is tightly controlled to ensure that replication origins fire only once per cycle and that consecutive S-phases are separated by mitosis.
Porter Andrew CG
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MPS1 is involved in the HPV16-E7-mediated centrosomes amplification
Cell Division, 2021 Background It has been reported that the oncoprotein E7 from human papillomavirus type 16 (HPV16-E7) can induce the excessive synthesis of centrosomes through the increase in the expression of PLK4, which is a transcriptional target of E2F1. On the other
Yair Alfaro-Mora +7 more
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Role of microRNAs in regulation of doxorubicin and paclitaxel responses in lung tumor cells
Cell Division, 2023 Lung cancer as the leading cause of cancer related mortality is always one of the main global health challenges. Despite the recent progresses in therapeutic methods, the mortality rate is still significantly high among lung cancer patients. A wide range
Amirhosein Maharati, Meysam Moghbeli
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Cell Division, 2011 Background Recently, interest in phytochemicals from traditional Chinese medicinal herbs with the capability to inhibit cancer cells growth and proliferation has been growing rapidly due to their nontoxic nature.
Song Baoan +7 more
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Cell Division, 2019 The anaphase-promoting complex/cyclosome (APC/C) is a multi-subunit, multifunctional ubiquitin ligase that controls the temporal degradation of numerous cell cycle regulatory proteins to direct the unidirectional cell cycle phases.
Shivangee Bansal, Swati Tiwari
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CRY arrests Cop1 to regulate circadian rhythms in mammals
Cell Division, 2019 Cryptochromes (CRYs) are UVA and blue light photoreceptors present in all major evolutionary lineages ranging from cyanobacteria to plants and animals, including mammals. In plants, blue light activates CRYs to induce photomorphogenesis by inhibiting the
Choogon Lee
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Transient defects of mitotic spindle geometry and chromosome segregation errors
Cell Division, 2012 Assembly of a bipolar mitotic spindle is essential to ensure accurate chromosome segregation and prevent aneuploidy, and severe mitotic spindle defects are typically associated with cell death. Recent studies have shown that mitotic spindles with initial
Silkworth William T, Cimini Daniela
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