Results 41 to 50 of about 13,269,236 (369)
Background Infantile hemangioma (IH) is a benign vascular neoplasm that arises from the abnormal proliferation of endothelial cells and enhanced angiogenesis. Recently, propranolol has been found to be effective in the management of IH, suggesting that β-
Ji Yi+5 more
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Gauchos and ochos: a Wee1-Cdk tango regulating mitotic entry
The kinase Wee1 has been recognized for a quarter century as a key inhibitor of Cyclin dependent kinase 1 (Cdk1) and mitotic entry in eukaryotes. Nonetheless, Wee1 regulation is not well understood and its large amino-terminal regulatory domain (NRD) has
Enders Greg H
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Resolving RAD51C function in late stages of homologous recombination
DNA double strand breaks are efficiently repaired by homologous recombination. One of the last steps of this process is resolution of Holliday junctions that are formed at the sites of genetic exchange between homologous DNA.
Kuznetsov Sergey G, Sharan Shyam K
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Influence of cell cycle phase on calcification in the coccolithophore Emiliania huxleyi [PDF]
Calcification of the cosmopolitan coccolithophore species Emiliania huxleyi was investigated in relation to the cell division cycle with the use of batch cultures.
Antia, Avan+2 more
core +1 more source
During mitosis, correct bipolar chromosome attachment to the mitotic spindle is an essential prerequisite for the equal segregation of chromosomes. The spindle assembly checkpoint can prevent chromosome segregation as long as not all chromosome pairs ...
Maia André F+2 more
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Reconstruction of the kinetochore: a prelude to meiosis
In eukaryotic organisms, chromosomes are spatially organized within the nucleus. Such nuclear architecture provides a physical framework for the genetic activities of chromosomes, and changes its functional organization as the cell moves through the ...
Haraguchi Tokuko+2 more
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FtsZ of filamentous, heterocyst-forming cyanobacteria has a conserved N-Terminal peptide required for normal FtsZ polymerization and cell division [PDF]
Filamentous cyanobacteria grow by intercalary cell division, which should involve distinct steps compared to those producing separate daughter cells. The N-terminal region of FtsZ is highly conserved in the clade of filamentous cyanobacteria capable of ...
Camargo Bernal, Sergio+6 more
core +4 more sources
p27kip1 at the crossroad between actin and microtubule dynamics
The p27kip1 protein, mainly known as a negative regulator of cell proliferation, has also been involved in the control of other cellular processes, including the regulation of cytoskeleton dynamics.
Gian Luca Rampioni Vinciguerra+5 more
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Single-cell spatial reconstruction reveals global division of labor in the mammalian liver
The mammalian liver consists of hexagon-shaped lobules that are radially polarized by blood flow and morphogens. Key liver genes have been shown to be differentially expressed along the lobule axis, a phenomenon termed zonation, but a detailed genome ...
K. B. Halpern+15 more
semanticscholar +1 more source
The dual nature of TDC – bridging dendritic and T cells in immunity
TDC are hematopoietic cells combining dendritic and T cell features. They reach secondary lymphoid organs (SLOs) and peripheral organs (liver and lungs) after FLT3‐dependent development in the bone marrow and maturation in the thymus. TDC are activated and enriched in SLOs upon viral infection, suggesting that they might play unique immune roles, since
Maria Nelli, Mirela Kuka
wiley +1 more source