Results 71 to 80 of about 12,176,123 (363)

Repetitive centromeric satellite RNA is essential for kinetochore formation and cell division

Journal of Cell Biology, 2014
Chromosome segregation requires centromeres on every sister chromatid to correctly form and attach the microtubule spindle during cell division. Even though centromeres are essential for genome stability, the underlying centromeric DNA is highly variable
Silvana Rošić, Florian Köhler, S. Erhardt   +2 more
semanticscholar   +1 more source

Forward Genetic Dissection of Biofilm Development by Fusobacterium nucleatum: Novel Functions of Cell Division Proteins FtsX and EnvC. [PDF]

, 2018
Fusobacterium nucleatum is a key member of the human oral biofilm. It is also implicated in preterm birth and colorectal cancer. To facilitate basic studies of fusobacterial virulence, we describe here a versatile transposon mutagenesis procedure and a ...
Abu Amar Mohamed Al Mamun, Asis Das, Bo Hu, Chenggang Wu, Hui Wu, Hung Ton-That, Jianhua Gu, Ju Huck Lee, Marvin Whiteley, Melissa D’Amore, Truc Thanh Luong   +10 more
core   +2 more sources

Characterization of fungal carbonyl sulfide hydrolase belonging to clade D β‐carbonic anhydrase

FEBS Letters, EarlyView.
Here, we performed a functional analysis of the fungal enzymes belonging to clade D of the β‐class carbonic anhydrase family (β‐D‐CA). The β‐D‐CAs in the basidiomycete Gloeophyllum trabeum and the ascomycete Trichoderma harzianum showed very low activity in the hydration of CO2 but exhibited high activity in the hydrolysis of carbonyl sulfide (COS ...
Ryuka Iizuka, Takahiro Ogawa, Rikako Tsukida, Keiichi Noguchi, David Hibbett, Yoko Katayama, Makoto Yoshida   +6 more
wiley   +1 more source

Preventing DNA over-replication: a Cdk perspective

Cell Division, 2008
The cell cycle is tightly controlled to ensure that replication origins fire only once per cycle and that consecutive S-phases are separated by mitosis.
Porter Andrew CG
doaj   +1 more source

Stochastic stem cell models with mutation: A comparison of asymmetric and symmetric divisions [PDF]

arXiv, 2020
In order to fulfill cell proliferation and differentiation through cellular hierarchy, stem cells can undergo either asymmetric or symmetric divisions. Recent studies pay special attention to the effect of different modes of stem cell division on the lifetime risk of cancer, and report that symmetric division is more beneficial to delay the onset of ...
arxiv  

Mathematical modeling of heterogeneous stem cell regeneration: from cell division to Waddington's epigenetic landscape [PDF]

arXiv, 2023
Stem cell regeneration is a crucial biological process for most self-renewing tissues during the development and maintenance of tissue homeostasis. In developing the mathematical models of stem cell regeneration and tissue development, cell division is the core process connecting different scale biological processes and leading to changes in cell ...
arxiv  

Concerted control of Escherichia coli cell division

Proceedings of the National Academy of Sciences of the United States of America, 2014
Significance The decisional process controlling cell division is a long-standing question in biology, but the answers were traditionally hindered by limited statistics on single cells.
Matteo Osella, E. Nugent, M. Cosentino Lagomarsino   +2 more
semanticscholar   +1 more source

Deterministic and stochastic descriptions of gene expression dynamics

, 2012
A key goal of systems biology is the predictive mathematical description of gene regulatory circuits. Different approaches are used such as deterministic and stochastic models, models that describe cell growth and division explicitly or implicitly etc ...
A.M. Walczak, C. Tan, C.V. Rao, D.L. Cook, David Gomez, E. Andrianantoandro, E.M. Ozbudak, H. Bremer, H.H. McAdams, I. Golding, J. Hasty, J. Hasty, J. Paulsson, J. Paulsson, J. Peccoud, J. Yu, J.A. Bernstein, J.L. Spudich, K. Nath, L. Bintu, L. Cai, M. Kaern, M. Scott, M. Scott, M. Thattai, M.B. Elowitz, M.E. Csete, M.E. Wall, M.S. Ko, N. Brenner, N. Mitarai, N.A. Cookson, N.J. Guido, O.G. Berg, O.G. Berg, P. Guptasarma, P. Wang, P.S. Swain, R. Kwok, Rahul Marathe, S. Cooper, S. Cooper, S. Klumpp, S. Klumpp, S. Klumpp, S. Klumpp, S. Klumpp, S. Reeh, Stefan Klumpp, U. Alon, Veronika Bierbaum, Y. Taniguchi   +51 more
core   +1 more source

Effects of cell cycle noise on excitable gene circuits [PDF]

, 2016
We assess the impact of cell cycle noise on gene circuit dynamics. For bistable genetic switches and excitable circuits, we find that transitions between metastable states most likely occur just after cell division and that this concentration effect ...
Bennett, Matthew R., Gupta, Chinmaya, Josić, Krešimir, Ott, William, Veliz-Cuba, Alan   +4 more
core   +3 more sources

A histidine‐rich extension of the mitochondrial F0 subunit ATP6 from the ice worm Mesenchytraeus solifugus increases ATP synthase activity in bacteria

FEBS Letters, EarlyView.
The glacier ice worm Mesenchytraeus solifugus survives year‐round at 0 °C. Its ATP6 subunit, which forms a regulatory component of the proton pore in mitochondrial ATP synthase, has a carboxy‐terminal extension not found in any other organism examined to date. Here, we show that fusion of this extension to the homologous AtpB protein in E. coli results
Truman Dunkley, Daniel H. Shain, Eric A. Klein   +2 more
wiley   +1 more source