Mutations in the Lipopolysaccharide Biosynthesis Pathway Interfere with Crescentin-Mediated Cell Curvature in Caulobacter crescentus [PDF]
, 2010 Bacterial cell morphogenesis requires coordination among multiple cellular systems, including the bacterial cytoskeleton and the cell wall. In the vibrioid bacterium Caulobacter crescentus, the intermediate filament-like protein crescentin forms a cell
Ausmees, Nora +7 more
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The subnuclear localization of tRNA ligase in yeast [PDF]
, 1987 Yeast tRNA ligase is an enzyme required for tRNA splicing. A study by indirect immune fluorescence shows that this enzyme is localized in the cell nucleus. At higher resolution, studies using indirect immune electron microscopy show this nuclear location
Abelson, John, Clark, Michael W.
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Formation of the postmitotic nuclear envelope from extended ER cisternae precedes nuclear pore assembly [PDF]
, 2011 During mitosis, the nuclear envelope merges with the endoplasmic reticulum (ER), and nuclear pore complexes are disassembled. In a current model for reassembly after mitosis, the nuclear envelope forms by a reshaping of ER tubules.
Anderson +48 more
core +4 more sources
Phosphoproteins and protein-kinase activity in isolated envelopes of pea (Pisum sativum L.) chloroplasts [PDF]
, 1985 A protein kinase was found in envelope membranes of purified pea (Pisum sativum L.) chloroplasts. Separation of the two envelope membranes showed that most of the enzyme activity was localized in the outer envelope.
D.G. Robinson +17 more
core +1 more source
HIV-Envelope–Dependent Cell-Cell Fusion: Quantitative Studies [PDF]
The Scientific World JOURNAL, 2009 Interactionin vitrobetween cells infected with human immunodeficiency virus (HIV) and surrounding, uninfected, target cells often leads to cell fusion and the formation of multinucleated cells, called syncytia. The presence in HIV-infected individuals of virus strains able to induce syncytia in cultures of T cells is associated with disease progression
Leonor Huerta +7 more
openaire +3 more sources
Mutations That Alter the Bacterial Cell Envelope Increase Lipid Production
mBio, 2017 Lipids from microbes offer a promising source of renewable alternatives to petroleum-derived compounds. In particular, oleaginous microbes are of interest because they accumulate a large fraction of their biomass as lipids.
Kimberly C. Lemmer +9 more
doaj +1 more source
A Barrier to Entry: Examining the Bacterial Outer Membrane and Antibiotic Resistance
Applied Sciences, 2023 Gram-negative bacteria can resist antibiotics by changing the permeability via their outer membrane. These bacteria have a complex cell envelope that incorporates an outer membrane separating the periplasm from the external environment.
Ishan Ghai
doaj +1 more source
In vitro and in vivo screening for novel essential cell-envelope proteins in Pseudomonas aeruginosa [PDF]
, 2015 The Gram-negative bacterium Pseudomonas aeruginosa represents a prototype of multi-drug resistant opportunistic pathogens for which novel therapeutic options are urgently required.
Bragonzi, Alessandra +5 more
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The bacterial cell envelope [PDF]
Philosophical Transactions of the Royal Society B: Biological Sciences, 2015 Antonie van Leeuwenhoek, a draper from Delft, using a tiny homemade microscope, first described microbes or ‘animalcules’ in a number of letters to the Royal Society. The letters specifically describe ‘animalcules’ in pepper water in 1676 (published 1677). The famous drawing of a swimming animalcule from a scraping of his teeth was in a letter of 1684 (
Colin Kleanthous, Judith P. Armitage
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A Biological Signature for the Inhibition of Outer Membrane Lipoprotein Biogenesis
mBio, 2022 The outer membrane (OM) of Gram-negative bacteria is an essential organelle that acts as a formidable barrier to antibiotics. Increasingly prevalent resistance to existing drugs has exacerbated the need for antibiotic discovery efforts targeting the OM ...
Kelly M. Lehman +2 more
doaj +1 more source