Results 201 to 210 of about 5,182,387 (300)

Salmonella enterica serovar typhi limits the potency of typhoid toxin and ADP‐ribosylating toxin AB to establish a persistent infection

FEBS Open Bio, EarlyView.
The two catalytic subunits of typhoid toxin dissociate from the holotoxin in the ER of an intoxicated cell, but only CdtB exits the ER to generate immunosuppressive effects. PltA is retained in the ER and sequestered from its cytosolic target, thus allowing the anti‐inflammatory effects of CdtB to promote intestinal colonization.
Maria C. Zabala‐Rodriguez, Juliette K. Tinker, Teresa Frisan, Taj Azarian, Ken Teter   +4 more
wiley   +1 more source

Beyond local control: radiotherapy-immunotherapy combinations from <i>in situ</i> vaccination to systemic immune remodeling. [PDF]

Front Genet
Wen Y, Cheng N, Zhou S, Zhu H, Ge Q.
europepmc   +1 more source

A minimal cellulosome‐like system in Cellulosilyticum lentocellum

FEBS Open Bio, EarlyView.
Cellulose‐degrading bacteria typically use cellulosomes, large multi‐enzyme complexes on a scaffold protein. In Cellulosilyticum lentocellum, we characterise a far smaller arrangement, a single scaffold bound to one cellulase through a single cohesin‐dockerin interaction.
John Allan, Amias Alstrom‐Moore, Gary W Black   +2 more
wiley   +1 more source

A Novel Binary Particle Fractionation Technique

Hill, Marytn, Harris, Nick, Glynne-Jones, Peter, Boltryk, Rosemary   +3 more
core   +1 more source

RNA-Binding Protein Occupancy Composition Predicts Long Noncoding RNA Subcellular Localization. [PDF]

Int J Mol Sci
Tani H.
europepmc   +1 more source

Type I interferons modulate autophagy to shape gemcitabine response in pancreatic cancer cells

FEBS Open Bio, EarlyView.
Type I interferons differentially modulate autophagy and the response of pancreatic cancer cells to gemcitabine. IFNα2b stimulates autophagic flux and protects cells from gemcitabine‐induced cell death, contributing to chemoresistance. In contrast, IFNβ1a inhibits autophagosome formation and enhances gemcitabine‐induced cell death, resulting in ...
Lucy E. Bonilla, Martín M. Ledesma, Santiago A. Behr, Matías A. Pibuel, María L. Palanek, Daniel H. Grasso, Maria N. Garcia, Juan Garona, Silvina L. Lompardía, Elida Álvarez, Daniela L. Papademetrio   +10 more
wiley   +1 more source

Automated zonal-rotor CsCl ultracentrifugation with ÄKTA-based fractionation removes empty and intermediate AAV capsids. [PDF]

Mol Ther Adv
Horita K, Miyauchi R, Yamamoto H, Yamazaki Y, Nagatomo K, Aburatani T, Takeda S, Baba S.   +7 more
europepmc   +1 more source

Identification and characterization of a gene conferring stress resistance in Escherichia coli and cyanobacteria

FEBS Open Bio, EarlyView.
Functional screening identified PcSyn14890, a cyanobacteria‐specific protein that enhances growth and stress resistance in E. coli and Synechocystis PCC6803. Although we expected it to function as a molecular chaperone, it was unable to protect against thermal aggregation of GAPDH.
Akiyo Yamada, Takaaki Tanaka, Manaka Uehara, Keigo Nakano, Ken Morishima, Rintaro Inoue, Masaaki Sugiyama, Masafumi Yohda   +7 more
wiley   +1 more source

Radiotherapy for Merkel cell carcinoma: recommendations from the DEGRO Dermatooncology Working Group. [PDF]

Strahlenther Onkol
Elsayad K, Falke I, Trommer M, Jost T, Rühle A, Gawish A, Roohani S, Glowka A, Hecht M, Gkika E, Hering K, König L, Corradini S, Eich HT, Vordermark D.   +14 more
europepmc   +1 more source