Results 141 to 150 of about 20,216,403 (408)
JTCVS Open, 2021 Objectives: To establish a protocol to prepare and transplant clinical-grade human induced pluripotent stem cell (hiPSC)-derived cardiac tissues (HiCTs) and to evaluate the therapeutic potential in an animal myocardial infarction (MI) model.
Hiroaki Osada, MD, PhD +6 more
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A stepwise emergence of evolution in the RNA world
FEBS Letters, EarlyView.How did biological evolution emerge from chemical reactions? This perspective proposes a gradual scenario of self‐organization among RNA molecules, where catalytic feedback on random mixtures plays the central role. Short oligomers cross‐ligate, and self‐assembly enables heritable variations. An event of template‐externalization marks the transition to
Philippe Nghe
wiley +1 more source
THE EFFECT OF DILUTION OF PLASMA MEDIUM ON THE GROWTH AND FAT ACCUMULATION OF CELLS IN TISSUE CULTURES [PDF]
, 1914 Robert A. Lambert
openalex +1 more source
Interplay between cell growth and cell cycle in plants.
Journal of Experimental Botany, 2014 The growth of organs and whole plants depends on both cell growth and cell-cycle progression, but the interaction between both processes is poorly understood.
R. Sablowski, Marcelo Carnier Dornelas
semanticscholar +1 more source
Molecular Therapy: Nucleic Acids, 2018 Highly active antiretroviral therapy (HAART) has markedly prolonged the prognosis of HIV-1 patients. However, lifelong dependency on HAART is a continuing challenge, and an effective therapeutic is much desired.
Kei Higaki +11 more
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AMPK activation reverts mouse epiblast stem cells to naive state
iScience, 2021 Summary: Despite increasing knowledge on primed and naive pluripotency, the cell signaling that regulates the pluripotency type in stem cells remains not fully understood.
Yajing Liu +4 more
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BIOCHEMICAL ASPECTS OF THE CELL GROWTH OF ESCHERICHIA COLI AS STUDIED BY THE METHOD OF SYNCHRONOUS CULTURE [PDF]
, 1956 Yoichi Maruyama
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The TSC1-TSC2 complex: a molecular switchboard controlling cell growth.
Biochemical Journal, 2008 TSC1 and TSC2 are the tumour-suppressor genes mutated in the tumour syndrome TSC (tuberous sclerosis complex). Their gene products form a complex that has become the focus of many signal transduction researchers. The TSC1-TSC2 (hamartin-tuberin) complex,
Jingxiang Huang, B. Manning
semanticscholar +1 more source
FEBS Letters, EarlyView.The enzyme 5‐lipoxygenase (5‐LOX) catalyzes the first step in the biosynthesis of leukotrienes (LTs) involved in inflammatory pathophysiology. After cellular stimulation, 5‐LOX translocates to the nucleus, interacting with the 5‐LOX‐activating protein (FLAP) to form LTA4 from arachidonic acid (AA).
Erik Romp +5 more
wiley +1 more source
Materials & Design, 2021 Osteoarthritis (OA) is one of the most common chronic diseases, causing degenerative changes in articular cartilage and subchondral bones. To date, there is no effective drug to delay the progression of OA in clinical practice.
Rongshuai Yang +8 more
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