Results 231 to 240 of about 5,651,556 (349)

ZBTB7A regulates CD95-mediated cell growth in colorectal cancer cell lines. [PDF]

PLoS One
Bie Y, Bie M, Liu W, Tao S, Xing H, Kuang L, Song Y.   +6 more
europepmc   +1 more source

Expression of key enzymes of purine and pyrimidine metabolism in a hepatocyte-derived cell line at different phases of the growth cycle

, 1990
Doris Mayer, Yutaka Natsumeda, Tadashi Ikegami, Mary A. Faderan, May S. Lui, Jahangir Emrani, Melissa A. Reardon, Edith Oláh, George Weber   +8 more
openalex   +2 more sources

Role of Insulin-Like Growth Factor Binding Protein-2 and Its Limited Proteolysis in Neuroblastoma Cell Proliferation: Modulation by Transforming Growth Factor-  and Retinoic Acid [PDF]

, 1997
M. Menouny
openalex   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

Inhibition of HER2 signaling and breast cancer cell growth with a novel antibody targeting HER2 ECD III/IV. [PDF]

PLoS One
Liu C, Ren Y, Luo X, Zhou P, Du X, Wang Q, Han X, Xu Y, Wang P, Zhao D, Yang H.   +10 more
europepmc   +1 more source

Effect of chemotherapy on passenger mutations in metastatic colorectal cancer

Molecular Oncology, EarlyView.
Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui, Matthew A. Cottam, Muhammad Bilal Mirza, Keeli B. Lewis, Kristen K. Ciombor, Mary Kay Washington, Kamran Idrees   +6 more
wiley   +1 more source

Bacteriophage FNU1 negates <i>Fusobacterium nucleatum</i> induced cell growth, migration and chemotherapy resistance in gastrointestinal cancer cells. [PDF]

Front Cell Infect Microbiol
Kabwe M, Ayelign B, Afshar-Sterle S, Buchert M, Tucci J.   +4 more
europepmc   +1 more source

microRNA-141 inhibits thyroid cancer cell growth and metastasis by targeting insulin receptor substrate 2.

, 2016
Su Dong, Xianying Meng, Shuai Xue, Zewen Yan, Peiyou Ren, Jia Liu   +5 more
openalex   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

<i>KEAP1</i> mutations activate the NRF2 pathway to drive cell growth and migration, and attenuate drug response in thyroid cancer. [PDF]

Front Oncol
Bambach NE, Ricarte-Filho JC, Reichenberger ER, Hernandez-Padilla C, Hinkle K, Isaza A, Bauer AJ, Franco AT.   +7 more
europepmc   +1 more source