Results 31 to 40 of about 20,216,403 (408)
Podoplanin as an Attractive Target of CAR T Cell Therapy
Cells, 2020 To date, various kinds of cancer immunotherapy methods have been developed, but T cell immunotherapy is one of the most promising strategies. In general, T cell receptor (TCR) or chimeric antigen receptor (CAR) is used to modify the antigen specificity ...
Masazumi Waseda, Shin Kaneko
doaj +1 more source
Targeting Glycolysis with Epigallocatechin-3-Gallate Enhances the Efficacy of Chemotherapeutics in Pancreatic Cancer Cells and Xenografts. [PDF]
, 2019 Pancreatic cancer is a complex disease, in need of new therapeutic approaches. In this study, we explored the effect and mechanism of action of epigallocatechin-3-gallate (EGCG), a major polyphenol in green tea, alone and in combination with current ...
Hackman, Robert M +3 more
core +1 more source
From single-cell variability to population growth [PDF]
Phys. Rev. E 101, 012401 (2020), 2018 Single-cell experiments have revealed cell-to-cell variability in generation times and growth rates for genetically identical cells. Theoretical models relating the fluctuating generation times of single cells to the population growth rate are usually based on the assumption that the generation times of mother and daughter cells are uncorrelated.
arxiv +1 more source
Generation of Scaffoldless Hyaline Cartilaginous Tissue from Human iPSCs
Stem Cell Reports, 2015 Defects in articular cartilage ultimately result in loss of joint function. Repairing cartilage defects requires cell sources. We developed an approach to generate scaffoldless hyaline cartilage from human induced pluripotent stem cells (hiPSCs).
Akihiro Yamashita +7 more
doaj +1 more source
Inflating bacterial cells by increased protein synthesis. [PDF]
, 2015 Understanding how the homeostasis of cellular size and composition is accomplished by different organisms is an outstanding challenge in biology. For exponentially growing Escherichia coli cells, it is long known that the size of cells exhibits a strong ...
Basan, Markus +6 more
core +2 more sources
Frontiers in Plant Science, 2021 In the fibers of many plant species after the formation of secondary cell walls, cellulose-enriched cell wall layers (often named G-layers or tertiary cell walls) are deposited which are important in many physiological situations.
Anna Petrova +5 more
doaj +1 more source
Circadian rhythm and cell population growth [PDF]
, 2010 Molecular circadian clocks, that are found in all nucleated cells of mammals, are known to dictate rhythms of approximately 24 hours (circa diem) to many physiological processes.
Bekkal Brikci +27 more
core +4 more sources
Orphanet Journal of Rare Diseases, 2022 Background Fibrodysplasia ossificans progressiva (FOP) is a rare genetic disease characterized by progressive heterotopic ossification (HO) in soft tissues due to a heterozygous mutation of the ACVR1A gene (FOP-ACVR1A), which erroneously transduces the ...
Hirotsugu Maekawa +10 more
doaj +1 more source
Why cells grow and divide? General growth mechanism and how it defines cells' growth, reproduction and metabolic properties [PDF]
Biophysical Reviews and Letters, 2015, 10(4), 209-256, 2016 We consider a general growth mechanism, which acts at cellular level and above (organs, systems and whole organisms). Using its mathematical representation, the growth equation, we study the growth and division mechanisms of amoeba and fission yeast Schizosaccharomyces pombe.
arxiv +1 more source
Cancer Medicine, 2018 To study the regulatory effect of lncRNA HOTAIR/miR‐20a‐5p/HMGA2 axis on breast cancer (BC) cell growth, cell mobility, invasiveness, and apoptosis. The microarray data of lncRNAs and mRNAs with differential expression in BC tissues were analyzed in the ...
Wenyan Zhao +4 more
semanticscholar +1 more source