Results 11 to 20 of about 14,501,441 (297)

Melanoma Cell-Intrinsic PD-1 Receptor Functions Promote Tumor Growth. [PDF]

, 2015
Therapeutic antibodies targeting programmed cell death 1 (PD-1) activate tumor-specific immunity and have shown remarkable efficacy in the treatment of melanoma. Yet, little is known about tumor cell-intrinsic PD-1 pathway effects.
Kleffel, Sonja, Posch, Christian, Frank, Markus H, Elco, Christopher P, Lee, Nayoung, Cozzio, Antonio, Lian, Christine G, Zhan, Qian, Murphy, George F, Sharpe, Arlene H, Mihm, Martin C, Dummer, Reinhard, Schatton, Tobias, Hoetzenecker, Wolfram, Schlapbach, Christoph, Guenova, Emmanuella, Juneja, Vikram R, Barthel, Steven R, Flaherty, Keith T, Mueller, Hansgeorg, Thomi, Rahel, Kupper, Thomas S   +21 more
core   +2 more sources

Mechanics of cell growth [PDF]

Mechanics Research Communications, 2012
Cell growth describes an essential feature of biological tissues. This growth process may be modeled by using a set of relatively simple governing equations based on the axioms of mass and momentum balance, and using a continuum framework that describes cells and tissues as mixtures of a solid matrix, a solvent and multiple solutes.
Gerard A, Ateshian, Barclay, Morrison, Jeffrey W, Holmes, Clark T, Hung   +3 more
openaire   +2 more sources

Effects of the vasoactive intestinal peptide (VIP) and related peptides on glioblastoma cell growth in vitro [PDF]

, 2003
The growth rate of numerous cancer cell lines is regulated in part by actions of neuropeptides of the vasoactive intestinal peptide (VIP) family, which also includes pituitary adenylate cyclase-activating peptide (PACAP), glucagon, and peptide histidine ...
Dufès, Christine, Alleaume, Céline, Olivier, Jean-Christophe, Montoni, Alicia, Muller, Jean-Marc   +4 more
core   +4 more sources

Craniofacial growth theory and orthodontic treatment

, 1990
http://babel.hathitrust.org/cgi/pt?id=uc1.l0061452249;view=2up;ui=fullscreen#page/n0/mode ...
Symposium on Craniofacial Growth
core   +7 more sources

Retinoic acid regulates erythropoietin production cooperatively with hypoxia-inducible factors in human iPSC-derived erythropoietin-producing cells

Scientific Reports, 2021
Erythropoietin (EPO) is a crucial hormone for erythropoiesis and produced by adult kidneys. Insufficient EPO production in chronic kidney disease (CKD) can cause renal anemia.
Naoko Katagiri, Hirofumi Hitomi, Shin-Ichi Mae, Maki Kotaka, Li Lei, Takuya Yamamoto, Akira Nishiyama, Kenji Osafune   +7 more
doaj   +1 more source

A clinically applicable and scalable method to regenerate T-cells from iPSCs for off-the-shelf T-cell immunotherapy

Nature Communications, 2021
T-cell immunotherapies, such as CAR-T immunotherapy, are being developed against a wide variety of diseases. Here the authors report the feeder-free, scalable differentiation of human induced pluripotent cells (iPSCs) to T-cells with T-cell receptor ...
Shoichi Iriguchi, Yutaka Yasui, Yohei Kawai, Suguru Arima, Mihoko Kunitomo, Takayuki Sato, Tatsuki Ueda, Atsutaka Minagawa, Yuta Mishima, Nariaki Yanagawa, Yuji Baba, Yasuyuki Miyake, Kazuhide Nakayama, Maiko Takiguchi, Tokuyuki Shinohara, Tetsuya Nakatsura, Masaki Yasukawa, Yoshiaki Kassai, Akira Hayashi, Shin Kaneko   +19 more
doaj   +1 more source

Growth regulation in Hydra. Relationship between epithelial cell cycle length and growth rate [PDF]

, 1984
The relationship between epithelial cell production and growth rate was investigated in Hydra attenuata under different feeding regimes. The increase of epithelial cell number was compared to the duration of the epithelial cell cycle using standard ...
Bosch, Thomas C. G., David, Charles N.
core   +1 more source

Heparan sulfate functions are altered in the osteoarthritic cartilage

Arthritis Research & Therapy, 2020
Background Heparan sulfate (HS) proteoglycans (PG) may be found at the chondrocyte surface and in the pericellular cartilage matrix, and are involved in cell-cell and cell-matrix interactions.
Sara Shamdani, Sandrine Chantepie, Camille Flageollet, Nadia Henni-Chebra, Yohann Jouan, Florent Eymard, Eric Hay, Martine Cohen-Solal, Dulce Papy-Garcia, Xavier Chevalier, Patricia Albanese   +10 more
doaj   +1 more source

The therapeutic potential of multiclonal tumoricidal T cells derived from tumor infiltrating lymphocyte-1derived iPS cells

Communications Biology, 2021
Ito et al. generated and characterized multiclonal tumoricidal T cells derived from tumor infiltrating lymphocyte-derived iPS cells (TIL-iPSC) using human colorectal cancer specimens.
Takeshi Ito, Yohei Kawai, Yutaka Yasui, Shoichi Iriguchi, Atsutaka Minagawa, Tomoko Ishii, Hiroyuki Miyoshi, M. Mark Taketo, Kenji Kawada, Kazutaka Obama, Yoshiharu Sakai, Shin Kaneko   +11 more
doaj   +1 more source

A Drosophila RNAi library modulates Hippo pathway-dependent tissue growth

Nature Communications, 2016
Drosophila RNAi libraries are commonly used to perform large-scale functional genetics screens in vivo. Here the authors find that a subset of lines from the VDRC KK RNAi line cause false-positive enhancement of the Hippo pathway, and provide a strain ...
Joseph H.A. Vissers, Samuel A. Manning, Aishwarya Kulkarni, Kieran F. Harvey   +3 more
doaj   +1 more source