Results 21 to 30 of about 3,364,337 (313)

Podoplanin as an Attractive Target of CAR T Cell Therapy

Cells, 2020
To date, various kinds of cancer immunotherapy methods have been developed, but T cell immunotherapy is one of the most promising strategies. In general, T cell receptor (TCR) or chimeric antigen receptor (CAR) is used to modify the antigen specificity ...
Masazumi Waseda, Shin Kaneko
doaj   +1 more source

Intrusive growth of sclerenchyma fibers [PDF]

, 2010
Intrusive growth is a type of cell elongation when the rate of its longitudinal growth is higher than that of surrounding cells; therefore, these cells intrude between the neighboring cells penetrating the middle lamella.
Chernova, T.E., Gorshkova, T.A., Ageeva, M.V., Snegireva, A.V., Ebskamp, M., Amenitskii, S.I.   +5 more
core   +1 more source

Generation of Scaffoldless Hyaline Cartilaginous Tissue from Human iPSCs

Stem Cell Reports, 2015
Defects in articular cartilage ultimately result in loss of joint function. Repairing cartilage defects requires cell sources. We developed an approach to generate scaffoldless hyaline cartilage from human induced pluripotent stem cells (hiPSCs).
Akihiro Yamashita, Miho Morioka, Yasuhito Yahara, Minoru Okada, Tomohito Kobayashi, Shinichi Kuriyama, Shuichi Matsuda, Noriyuki Tsumaki   +7 more
doaj   +1 more source

Mathematical modelling of cancer invasion : implications of cell adhesion variability for tumour infiltrative growth patterns [PDF]

, 2014
Cancer invasion, recognised as one of the hallmarks of cancer, is a complex, multiscale phenomenon involving many inter-related genetic, biochemical, cellular and tissue processes at different spatial and temporal scales.
Trucu, Dumitru; id_orcid, Chaplain, Mark A. J., Domschke, Pia, Trucu, Dumitru, Gerisch, Alf   +4 more
core   +1 more source

Chemotaxis: a feedback-based computational model robustly predicts multiple aspects of real cell behaviour [PDF]

, 2011
The mechanism of eukaryotic chemotaxis remains unclear despite intensive study. The most frequently described mechanism acts through attractants causing actin polymerization, in turn leading to pseudopod formation and cell movement.
Haastert, Peter J.M. van,, Peter J M van Haastert, van Haastert, Peter J. M., van Haastert, Peter J.M., Matthew P. Neilson, Douwe M Veltman, Webb, Steven D., Insall, Robert H., Webb, Steven D.,, Neilson, Matthew P.,, Neilson, Matthew P., Matthew P Neilson, Douwe M. Veltman, Peter J. M. van Haastert, Insall, Robert H.,, Steven D Webb, Webb, Steven, Robert H Insall, John A. Mackenzie, Mackenzie, John A.,, John A Mackenzie, Veltman, Douwe M.,, Mackenzie, John A., Veltmahn, Douwe M., Veltman, Douwe M., Steven D. Webb, Robert H. Insall   +26 more
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Modulation of Peptidoglycan Synthesis by Recycled Cell Wall Tetrapeptides [PDF]

, 2020
The bacterial cell wall is made of peptidoglycan (PG), a polymer that is essential for the maintenance of cell shape and survival. During growth, bacteria remodel their PG, releasing fragments that are predominantly reinternalized and recycled.
Dorr, Tobias, Cava, Felipe, Hernandez, Sara B.,, Waldor, Matthew K., Hernandez, Sara B., Cava, Felipe,   +5 more
core   +1 more source

Reversal of an immunity associated plant cell death program by the growth regulator auxin [PDF]

, 2007
One form of plant immunity against pathogens involves a rapid host programmed cell death at the site of infection accompanied by resistance, termed the hypersensitive response (HR).
Suresh Gopalan, Gopalan Suresh, Gopalan, Suresh   +2 more
core   +2 more sources

Generation of macrophages with altered viral sensitivity from genome-edited rhesus macaque iPSCs to model human disease

Molecular Therapy: Methods & Clinical Development, 2021
Because of their close biological similarity to humans, non-human primate (NHP) models are very useful for the development of induced pluripotent stem cell (iPSC)-based cell and regenerative organ transplantation therapies.
Yoshihiro Iwamoto, Yohei Seki, Kahoru Taya, Masahiro Tanaka, Shoichi Iriguchi, Yasuyuki Miyake, Emi E. Nakayama, Tomoyuki Miura, Tatsuo Shioda, Hirofumi Akari, Akifumi Takaori-Kondo, Shin Kaneko   +11 more
doaj   +1 more source

The histone deacetylase inhibitor valproic acid alters growth properties of renal cell carcinoma in vitro and in vivo [PDF]

, 2008
Histone deacetylase (HDAC) inhibitors represent a promising class of antineoplastic agents which affect tumour growth, differentiation and invasion. The effects of the HDAC inhibitor valproic acid (VPA) were tested in vitro and in vivo on pre-clinical ...
Eva Juengel, Mickuckyte, Ausra, Hudak, Lukasz, Jones, Jon, Lukasz Hudak, Jüngel, Eva, Dietger Jonas, Blaheta, Roman A., Roman A. Blaheta, Wedel, Steffen Alexander, Ausra Mickuckyte, Jonas, Dietger, Jon Jones, Steffen Wedel   +13 more
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Cell Wall Layer Induced in Xylem Fibers of Flax Upon Gravistimulation Is Similar to Constitutively Formed Cell Walls of Bast Fibers

Frontiers in Plant Science, 2021
In the fibers of many plant species after the formation of secondary cell walls, cellulose-enriched cell wall layers (often named G-layers or tertiary cell walls) are deposited which are important in many physiological situations.
Anna Petrova, Liudmila Kozlova, Oleg Gorshkov, Alsu Nazipova, Marina Ageeva, Tatyana Gorshkova   +5 more
doaj   +1 more source