Results 41 to 50 of about 20,216,403 (408)

T cell growth factor: parameters of production and a quantitative microassay for activity.

Journal of Immunology, 1978
Several soluble factors have recently been associated with the proliferation and differentiation of thymus-derived lymphocytes. One of these factors present in medium conditioned by T cell mitogen-stimulated lymphocytes has the ability to promote the ...
S. Gillis, M. Ferm, Winny Ou, Kendall A. Smith   +3 more
semanticscholar   +1 more source

Mathematical modeling of cell population dynamics in the colonic crypt and in colorectal cancer [PDF]

, 2007
Colorectal cancer is initiated in colonic crypts. A succession of genetic mutations or epigenetic changes can lead to homeostasis in the crypt being overcome, and subsequent unbounded growth.
M. D. Johnston, C. M. Edwards, W. F. Bodmer, P. K. Maini, S. J. Chapman, Brittan, Preston, Ro, Giles, Okamoto, Potten, Li, Loeffler, Michor, Hanahan, Tomlinson, Renehan, Fearon, Paulus, Paulus, Gerike, Meineke, Boman, Hardy, Tomlinson   +24 more
core   +3 more sources

The Reciprocal Causation of the ASK1-JNK1/2 Pathway and Endoplasmic Reticulum Stress in Diabetes-Induced Cognitive Decline

Frontiers in Cell and Developmental Biology, 2020
Diabetes significantly induces cognitive dysfunction. Neuronal apoptosis is the main cause of diabetes-induced cognitive decline (DICD). Apoptosis signal-regulating kinase 1 (ASK1) and endoplasmic reticulum (ER) stress are remarkably activated by ...
Yanqing Wu, Yanqing Wu, Yuan Yuan, Chengbiao Wu, Ting Jiang, Beini Wang, Jun Xiong, Peipei Zheng, Yiyang Li, Jingyu Xu, Ke Xu, Yaqian Liu, Xiaokun Li, Jian Xiao   +13 more
doaj   +1 more source

Asymptotic decoupling of population growth rate and cell size distribution [PDF]

arXiv, 2022
The rate at which individual bacterial cells grow depends on the concentrations of cellular components such as ribosomes and proteins. These concentrations continuously fluctuate over time and are inherited from mother to daughter cells, leading to correlations between the growth rates of cells across generations.
arxiv  

Cell Biology of Hyphal Growth [PDF]

Microbiology Spectrum, 2017
ABSTRACT Filamentous fungi are a large and ancient clade of microorganisms that occupy a broad range of ecological niches. The success of filamentous fungi is largely due to their elongate hypha, a chain of cells, separated from each other by septa.
Steinberg, Gero, Peñalva, Miguel A, Riquelme, Meritxell, Wosten, Han, Harris, Steven D   +4 more
openaire   +3 more sources

Analysis of a stochastic model for bacterial growth and the lognormality of the cell-size distribution

, 2016
This paper theoretically analyzes a phenomenological stochastic model for bacterial growth. This model comprises cell division and the linear growth of cells, where growth rates and cell cycles are drawn from lognormal distributions.
Wakita, Jun-ichi, Yamamoto, Ken
core   +1 more source

Effects of the vasoactive intestinal peptide (VIP) and related peptides on glioblastoma cell growth in vitro [PDF]

, 2003
The growth rate of numerous cancer cell lines is regulated in part by actions of neuropeptides of the vasoactive intestinal peptide (VIP) family, which also includes pituitary adenylate cyclase-activating peptide (PACAP), glucagon, and peptide histidine ...
Alleaume, Céline, Dufès, Christine, Montoni, Alicia, Muller, Jean-Marc, Olivier, Jean-Christophe   +4 more
core   +1 more source

Benefits and risks of the hormetic effects of dietary isothiocyanates on cancer prevention [PDF]

, 2014
The isothiocyanate (ITC) sulforaphane (SFN) was shown at low levels (1-5 µM) to promote cell proliferation to 120-143% of the controls in a number of human cell lines, whilst at high levels (10-40 µM) it inhibited such cell proliferation.
A Arlt, A Giudice, A Herman-Antosiewicz, A Lau, A Lister, A Melchini, A Speciale, AA Alfadda, AJ Vargas, AT Dinkova-Kostova, AV Gasper, C Cornelius, C Fimognari, C Fimognari, Changhao Sun, CR Zhao, D Li, D Rand, D Ren, Daotai Nie, DD Zhang, DS Michaud, E Warwick, EJ Calabrese, EJ Calabrese, EJ Calabrese, EJ Calabrese, ER Hahm, F Ekiz, F Galgano, F Zanichelli, GM DeNicola, GR Fenwick, GS Omenn, HK Na, I Misiewicz, I Oehme, IS Santos, J Jakubikova, J Watson, JD Clarke, JD Hayes, JD Watson, JM Cramer, K Pietsch, K Suppipat, KA Moy, KL Cheung, L Gamet-Payrastre, L Kuang, L Ye, LN Barrera, LS Cooley, M McMahon, MB Sporn, MP Mattson, MP Mattson, P Sestili, P Shelton, PE Miller, R Brigelius-Flohe, RF Clayton, RK Thimmulappa, S Homma, SA McNaughton, SJ Jackson, SL Navarro, T Hara, T Nishikawa, T Xu, TG Son, TW Kensler, TW Kensler, V Calabrese, V Rungapamestry, W Hendrickx, Wei Wang, X Ma, X Yu, XJ Wang, Y Ji, Y Li, Y Mitsuishi, Y Shan, Y Zhang, Y Zhang, Y Zhang, Y Zhang, YJ Surh, Yongping Bao, YS Keum, Zhigang Zhou   +91 more
core   +7 more sources

Not So Fast: Cultivating miRs as Kinks in the Chain of the Cell Cycle. [PDF]

, 2017
In this issue of Cancer Cell, Hydbring and colleagues define a novel class of microRNAs (miRNAs), deemed cell-cycle-targeting miRNAs, that target several cyclins/CDKs, reduce tumor cell growth, and induce apoptosis.
Knudsen, Karen E., Schiewer, Matthew J.
core   +2 more sources

Pterosin B prevents chondrocyte hypertrophy and osteoarthritis in mice by inhibiting Sik3

Nature Communications, 2016
Therapies are needed for the prevention of chondrocyte hypertrophy and thinning of articular cartilage, features of osteoarthritic joint destruction. Here, the authors show that interfering with Sik3 signalling can increase the size of the chondrocyte ...
Yasuhito Yahara, Hiroshi Takemori, Minoru Okada, Azuma Kosai, Akihiro Yamashita, Tomohito Kobayashi, Kaori Fujita, Yumi Itoh, Masahiro Nakamura, Hiroyuki Fuchino, Nobuo Kawahara, Naoshi Fukui, Akira Watanabe, Tomoatsu Kimura, Noriyuki Tsumaki   +14 more
doaj   +1 more source