Results 21 to 30 of about 679,265 (269)
The transient receptor potential melastatin-subfamily member 8 (TRPM8) channels control Ca2+ homeostasis. Recent studies indicate that TRPM8 channels are aberrantly expressed and required for cellular proliferation in pancreatic adenocarcinoma.
Nelson S. Yee +5 more
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Background and Objectives: The effects of Ocimum tenuiflorum essential oil (OTEO) against gastric cancer remain unknown and merit investigation. Materials and Methods: In the present study, the anti-cancer activity of OTEO was examined in a human gastric
Wongwarut Boonyanugomol +8 more
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Molecular basis of mammalian cell invasion by Trypanosoma cruzi
Establishment of infection by Trypanosoma cruzi, the agent of Chagas' disease, depends on a series of events involving interactions of diverse parasite molecules with host components.
Nobuko Yoshida
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Cell Adhesion and Matrix Stiffness: Coordinating Cancer Cell Invasion and Metastasis
Metastasis is a multistep process in which tumor extracellular matrix (ECM) and cancer cell cytoskeleton interactions are pivotal. ECM is connected, through integrins, to the cell’s adhesome at cell–ECM adhesion sites and through them to the actin ...
Vasiliki Gkretsi +1 more
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Cell signaling during Trypanosoma cruzi invasion
Cell signaling is an essential requirement for mammalian cell invasion by Trypanosoma cruzi. Depending on the parasite strain and the parasite developmental form, distinct signaling pathways may be induced.
Fernando Yukio Maeda +2 more
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Objective: Pre-eclampsia (PE) is a major complication of pregnancy, but its pathogenesis is unclear. This study explored the role of LINC01128 in the progression of PE, and its interaction with miR-16 on the behaviors of trophoblasts.
Xinyuan Zhao +5 more
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EMT, the cytoskeleton, and cancer cell invasion [PDF]
The metastatic process, i.e. the dissemination of cancer cells throughout the body to seed secondary tumors at distant sites, requires cancer cells to leave the primary tumor and to acquire migratory and invasive capabilities. In a process of epithelial-mesenchymal transition (EMT), besides changing their adhesive repertoire, cancer cells employ ...
Yilmaz, Mahmut, Christofori, Gerhard
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IRON, INFLAMMATION AND INVASION OF CANCER CELLS [PDF]
Chronic inflammation is associated with the metastasis of tumor cells evolving from a benign tumor to disseminating cancer. Such a metastatic progression is fostered by the angiogenesis propelled by various mediators interacting at the site of tumor growth.
FISCHER-FODOR, EVA +3 more
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BackgroundSignal transducers and activators of transcription (STAT) transcription factors, a family of genes encoding transcription factors, have been linked to the development of numerous types of tumors.
Xiaodi Gong, Xiaojun Liu
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Fungal invasion of epithelial cells
Interaction between host cells and invasive Candida plays a large role in the pathogenicity of Candida species. Fungal-induced endocytosis and active penetration are the two distinct, yet complementary invasion mechanisms of invasive candidiasis. Induced endocytosis is a microorganism-triggered, epithelial-driven, clathrin-mediated and actin-dependent ...
Yang, Weiming +4 more
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