Results 21 to 30 of about 679,265 (269)

Aberrantly Over-Expressed TRPM8 Channels in Pancreatic Adenocarcinoma: Correlation with Tumor Size/Stage and Requirement for Cancer Cells Invasion

open access: yesCells, 2014
The transient receptor potential melastatin-subfamily member 8 (TRPM8) channels control Ca2+ homeostasis. Recent studies indicate that TRPM8 channels are aberrantly expressed and required for cellular proliferation in pancreatic adenocarcinoma.
Nelson S. Yee   +5 more
doaj   +1 more source

An In Vitro Anti-Cancer Activity of Ocimum tenuiflorum Essential Oil by Inducing Apoptosis in Human Gastric Cancer Cell Line

open access: yesMedicina, 2021
Background and Objectives: The effects of Ocimum tenuiflorum essential oil (OTEO) against gastric cancer remain unknown and merit investigation. Materials and Methods: In the present study, the anti-cancer activity of OTEO was examined in a human gastric
Wongwarut Boonyanugomol   +8 more
doaj   +1 more source

Molecular basis of mammalian cell invasion by Trypanosoma cruzi

open access: yesAnais da Academia Brasileira de Ciências, 2006
Establishment of infection by Trypanosoma cruzi, the agent of Chagas' disease, depends on a series of events involving interactions of diverse parasite molecules with host components.
Nobuko Yoshida
doaj   +1 more source

Cell Adhesion and Matrix Stiffness: Coordinating Cancer Cell Invasion and Metastasis

open access: yesFrontiers in Oncology, 2018
Metastasis is a multistep process in which tumor extracellular matrix (ECM) and cancer cell cytoskeleton interactions are pivotal. ECM is connected, through integrins, to the cell’s adhesome at cell–ECM adhesion sites and through them to the actin ...
Vasiliki Gkretsi   +1 more
doaj   +1 more source

Cell signaling during Trypanosoma cruzi invasion

open access: yesFrontiers in Immunology, 2012
Cell signaling is an essential requirement for mammalian cell invasion by Trypanosoma cruzi. Depending on the parasite strain and the parasite developmental form, distinct signaling pathways may be induced.
Fernando Yukio Maeda   +2 more
doaj   +1 more source

LINC01128 - miR-16 interaction regulates the migration and invasion of human chorionic trophoblast cells

open access: yesHypertension in Pregnancy, 2021
Objective: Pre-eclampsia (PE) is a major complication of pregnancy, but its pathogenesis is unclear. This study explored the role of LINC01128 in the progression of PE, and its interaction with miR-16 on the behaviors of trophoblasts.
Xinyuan Zhao   +5 more
doaj   +1 more source

EMT, the cytoskeleton, and cancer cell invasion [PDF]

open access: yesCancer and Metastasis Reviews, 2009
The metastatic process, i.e. the dissemination of cancer cells throughout the body to seed secondary tumors at distant sites, requires cancer cells to leave the primary tumor and to acquire migratory and invasive capabilities. In a process of epithelial-mesenchymal transition (EMT), besides changing their adhesive repertoire, cancer cells employ ...
Yilmaz, Mahmut, Christofori, Gerhard
openaire   +4 more sources

IRON, INFLAMMATION AND INVASION OF CANCER CELLS [PDF]

open access: yesMedicine and Pharmacy Reports, 2015
Chronic inflammation is associated with the metastasis of tumor cells evolving from a benign tumor to disseminating cancer.  Such a metastatic progression is fostered by the angiogenesis propelled by various mediators interacting at the site of tumor growth.
FISCHER-FODOR, EVA   +3 more
openaire   +2 more sources

In-depth analysis of the expression and functions of signal transducers and activators of transcription in human ovarian cancer

open access: yesFrontiers in Oncology, 2022
BackgroundSignal transducers and activators of transcription (STAT) transcription factors, a family of genes encoding transcription factors, have been linked to the development of numerous types of tumors.
Xiaodi Gong, Xiaojun Liu
doaj   +1 more source

Fungal invasion of epithelial cells

open access: yesMicrobiological Research, 2014
Interaction between host cells and invasive Candida plays a large role in the pathogenicity of Candida species. Fungal-induced endocytosis and active penetration are the two distinct, yet complementary invasion mechanisms of invasive candidiasis. Induced endocytosis is a microorganism-triggered, epithelial-driven, clathrin-mediated and actin-dependent ...
Yang, Weiming   +4 more
openaire   +2 more sources

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