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Cancer Informatics, 2010 Background While trying to integrate multiple data sets collected by different researchers, we noticed that the sample names were frequently entered inconsistently. Most of the variations appeared to involve punctuation, white space, or their absence, at the juncture between alphabetic and numeric portions of the cell line name.
Jing Wang +13 more
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Scientific Reports, 2022 Malignant pleural effusion (MPE) is an independent determinant of poor prognostic factor of non-small cell lung cancer (NSCLC). The course of anchorage independent growth within the pleural cavity likely reforms the innate molecular characteristics of ...
Ha-Young Seo +7 more
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Identification of Lilium ledebourii antiproliferative compounds against skin, bone and oral cancer cells [PDF]
Avicenna Journal of Phytomedicine, 2023 Objective: This study aimed at the evaluation of anti antiproliferative activity of Lonicera nummularifolia, Lilium ledebourii, Campsis radicans and Parthenocissus quinquefolia extracts.
Nastaran Partovi +3 more
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npj Genomic Medicine, 2022 Multifocal colorectal cancer (CRC) comprises both clonally independent primary tumors caused by inherited predisposition and clonally related tumors mainly due to intraluminal spreading along an intact basement membrane.
Nahyun Jeong +10 more
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Biomedicines, 2023 Monoclonal antibody-based therapy has shown efficacy against cancer, autoimmune, infectious, and inflammatory diseases. Multispecific antibodies (MsAbs), including trispecifics (tsAbs), offer enhanced therapeutic potential by targeting different epitopes.
Maria João Sebastião +7 more
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Advanced Science, 2022 Intratumor heterogeneity (ITH) stands as one of the main difficulties in the treatment of colorectal cancer (CRC) as it causes the development of resistant clones and leads to heterogeneous drug responses. Here, 12 sets of patient‐derived organoids (PDOs)
Soon‐Chan Kim +11 more
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Patient-derived glioblastoma cell lines with conserved genome profiles of the original tissue
Scientific Data, 2023 Glioblastoma (GBM) is the most lethal intracranial tumor. Sequencing technologies have supported personalized therapy for precise diagnosis and optimal treatment of GBM by revealing clinically actionable molecular characteristics.
Soon-Chan Kim +10 more
doaj +1 more source
Effective flow-through polishing strategies for knob-into-hole bispecific antibodies
Bioresources and Bioprocessing, 2022 Bispecific antibodies (bsAbs), though possessing great therapeutic potential, are extremely challenging to obtain at high purity within a limited number of scalable downstream processing steps.
Serene W. Chen +4 more
doaj +1 more source
Methods, 2014 We review the properties and uses of cell lines in Drosophila research, emphasizing the variety of lines, the large body of genomic and transcriptional data available for many of the lines, and the variety of ways the lines have been used to provide tools for and insights into the developmental, molecular, and cell biology of Drosophila and mammals.
Cherbas, Lucy, Gong, Lei
openaire +2 more sources
Bioresources and Bioprocessing, 2022 Bispecific antibodies (bsAbs) are therapeutically promising due to their ability to bind to two different antigens. However, the bsAb byproducts and impurities, including mispaired homodimers, half-antibodies, light chain mispairings, antibody fragments ...
Serene W. Chen +4 more
doaj +1 more source