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, 2015 The human colon adenocarcinoma cell line HT29, is not only used to study the biology of human colon cancers, but it is receiving special interest in studies focused on food digestion and bioavailability due to the ability to express characteristics of mature intestinal cells. In the differentiated phenotype, they are able to form a monolayer with tight
Martínez-Maqueda, D. +2 more
openaire +3 more sources
Cancer Informatics, 2010 Background While trying to integrate multiple data sets collected by different researchers, we noticed that the sample names were frequently entered inconsistently. Most of the variations appeared to involve punctuation, white space, or their absence, at the juncture between alphabetic and numeric portions of the cell line name.
Jing Wang +13 more
doaj +5 more sources
Briefings Bioinform., 2021 Cell line drug screening datasets can be utilized for a range of different drug discovery applications from drug biomarker discovery to building translational models of drug response.
D. Maeser, Robert F. Gruener, R. Huang
semanticscholar +1 more source
Identification of Lilium ledebourii antiproliferative compounds against skin, bone and oral cancer cells [PDF]
Avicenna Journal of Phytomedicine, 2023 Objective: This study aimed at the evaluation of anti antiproliferative activity of Lonicera nummularifolia, Lilium ledebourii, Campsis radicans and Parthenocissus quinquefolia extracts.
Nastaran Partovi +3 more
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Scientific Reports, 2022 Malignant pleural effusion (MPE) is an independent determinant of poor prognostic factor of non-small cell lung cancer (NSCLC). The course of anchorage independent growth within the pleural cavity likely reforms the innate molecular characteristics of ...
Ha-Young Seo +7 more
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npj Genomic Medicine, 2022 Multifocal colorectal cancer (CRC) comprises both clonally independent primary tumors caused by inherited predisposition and clonally related tumors mainly due to intraluminal spreading along an intact basement membrane.
Nahyun Jeong +10 more
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The Curious Case of the HepG2 Cell Line: 40 Years of Expertise
International Journal of Molecular Sciences, 2021 Liver cancer is the third leading cause of cancer death worldwide. Representing such a dramatic impact on our lives, liver cancer is a significant public health concern.
V. Arzumanian +2 more
semanticscholar +1 more source
Biomedicines, 2023 Monoclonal antibody-based therapy has shown efficacy against cancer, autoimmune, infectious, and inflammatory diseases. Multispecific antibodies (MsAbs), including trispecifics (tsAbs), offer enhanced therapeutic potential by targeting different epitopes.
Maria João Sebastião +7 more
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Advanced Science, 2022 Intratumor heterogeneity (ITH) stands as one of the main difficulties in the treatment of colorectal cancer (CRC) as it causes the development of resistant clones and leads to heterogeneous drug responses. Here, 12 sets of patient‐derived organoids (PDOs)
Soon‐Chan Kim +11 more
doaj +1 more source
Preclinical Models of Follicular Cell-Derived Thyroid Cancer: An Overview from Cancer Cell Lines to Mouse Models [PDF]
Endocrinology and Metabolism, 2022 The overall prognosis of thyroid cancer is excellent, but some patients have grossly invasive disease and distant metastases with limited responses to systemic therapies.
Min Ji Jeon, Bryan R. Haugen
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