Results 71 to 80 of about 1,625,980 (311)
Molecular Therapy: OncologyThere are very few syngeneic mouse cell line models available for gastric cancer owing to the rarity of stomach epithelium-specific promoter. Mouse cell line models are useful to study an immunologically intact tumor microenvironment, especially in the ...
Min-Jung Seo +12 more
doaj +1 more source
Photofrin II as an efficient radiosensitizing agent in an experimental tumor [PDF]
, 2001 Background and Objective: The use of ionizing irradiation as radiation therapy (RT) for tumor treatment represents a well-established method. The use of photodynamic therapy (PDT), especially with Photofrin II, for tumor treatment is also known. Chemical
Corti, L. +6 more
core +1 more source
Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Objective To compare the efficacy and safety of roxarestat versus recombinant human erythropoietin (rhEPO) in the management of renal anemia in patients undergoing maintenance hemodialysis. Methods This was a prospective, open‐label, randomized controlled trial.
Lingling Chen, Junjie Zhu, Qiaonan Ge
wiley +1 more source
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Cancer Management and Research, 2019 Wang H, Lou C, Ma N. miR-140-5p alleviates the aggressive progression of Wilms’ tumor through directly targeting TGFBR I gene. Cancer Manage Res.
Wang H, Lou C, Ma N
doaj
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Establishment and characterization ofmouse hepatic tumor cell line with luc2-tdT expression [PDF]
Jichu yixue yu linchuangObjective The mouse autologous tumor model H22 is more valuable for tumor immunological-related research. This paper aims to establish mouse hepatic tumor cell line (H22-luc2-tdT)that stably express the tandem-dimer tomato(tdTomato) and luciferase genes.
HAO Sijia, YANG Zhenli, BIAN Xiaocui, HOU Yuhong, LIU Yuqin
doaj +1 more source
PPAR-alpha: a novel target in pancreatic cancer [PDF]
, 2015 Background: Current targeted therapies in pancreatic cancer have been ineffective. The tumor stroma, including intra- and peri-tumoral inflammation and fibrosis, is increasingly implicated in pancreatic cancer.
Hua, Alexander Mach
core +1 more source
Evaluation of Microparticulate Ovarian Cancer Vaccine via Transdermal Route of Delivery [PDF]
, 2016 Ovarian cancer is the fifth most commonly occurring malignancy in women, with the highest mortality rate among all the gynecological tumors. Microparticulate vaccine can serve as an immunotherapeutic approach with a promising antigenic delivery system ...
Akalkotkar, Archana +3 more
core +2 more sources
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source